7 completed, 2 withdrawn, 1 recruiting, 1 unknown. 5 Not applicable, 3 Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 4, Recruiting 1 |
| Phase 1 | 3 | Completed 2, Withdrawn 1 |
| Phase 2 | 1 | Withdrawn 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Ensure Plus: new trials by email Literature Review of Ensure Plus trials Research Report on Ensure Plus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A High Protein Egg White Pudding for People With Kidney Failure (HiPE KF) Egg white protein pudding, : Ensure Plus - Kidney Failure, Frailty | Not applicable | Recruiting | Seven Oaks Hospital Chronic Disease Innovation Centre | 54 | 2025-07-25 | 2026-04-22 |
| Development of 4D Flow MRI for Risk Stratification of Variceal Bleeding in Cirrhosis Ensure Plus®, Pre-clinical validation contrast enhanced MRI, Clinical validation MRI - Cirrhosis, Liver, Gastroesophageal Varices | Completed | University of Wisconsin, Madison | 84 | 2021-10-28 | 2026-07-08 | |
| Evaluating Predictive Methods & Product Performance in Healthy Adults for Pediatric Patients, A Case Study: Furosemide Water, Parmalat™ Whole Milk, Similac Pro-Advance™ - Medication Absorption | Phase 1 | Withdrawn | Yale University | 2018-12-31 | 2019-01-18 | |
| A Trial to Investigate the Effect of Different Supplements on Fluid and Sodium Status in Short Bowel Vital 1.5, Ensure Plus - Short Bowel Syndrome | Not applicable | Completed | London North West Healthcare NHS Trust | 10 | 2016-01-01 | 2024-02-13 |
| Perioperative Oral Nutrition Intervention for Patients Undergoing Radical Cystectomy Ensure Plus®, Multivitamin - Bladder Cancer | Not applicable | Completed | Vanderbilt University | 60 | 2014-03-01 | 2017-03-29 |
| Improving Tolerance of Treatment of Pulmonary MAC Infections Zofran (8mg), Ensure - Mycobacterium Avium Complex, Adverse Effects | Phase 2 | Withdrawn | University of Florida | 2013-01-01 | 2013-04-04 | |
| Development Of An Innovative Panel of Methods To Measure Intestinal Macronutrient Digestion, Absorption, and Function Ensure plus - Cystic Fibrosis | Not applicable | Completed | Texas A&M University | 30 | 2010-11-15 | 2025-10-01 |
| Effectiveness of Oral Nutritional Supplements (ONS) in a Meals-on-Wheels Population Ensure Plus, Meals on Wheels - Elderly, Malnutrition | Not applicable | Completed | Texas Christian University | 91 | 2009-10-01 | 2014-06-13 |
| A Study of the Enzyme Activity and Safety of Pancrelipase in Patients With Severe Exocrine Pancreatic Insufficiency (EPI) Ensure Plus, Pancrelipase in combination with Ensure Plus - Exocrine Pancreatic Insufficiency, Pancreatitis, Chronic | Phase 1 | Completed | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 13 | 2008-07-01 | 2011-05-19 |
| Gastric and Intestinal Satiation in Obese and Normal Weight Healthy People ensure plus, standardized test meal - Endocrine System Diseases | Phase 1 | Completed | University Hospital, Basel, Switzerland | 65 | 2007-01-01 | 2011-10-20 |
| Trial of Enteral Nutrition Enriched With Eicosapentaenoic Acid (EPA) in Upper Gastrointestinal Cancer Surgery Prosure, Ensure Plus - Esophageal Cancer | Phase 4 | Unknown | University of Dublin, Trinity College | 120 | 2005-07-01 | 2008-11-13 |
Cerebral Palsy (1) · Cystic Fibrosis (1) · Endocrine System Diseases (1) · Esophageal Neoplasms (1) · Exocrine Pancreatic Insufficiency (1) · Frailty (1) · Liver Cirrhosis (1) · Malnutrition (1) · Mycobacterium avium-intracellulare Infection (1) · Pancreatitis (1) · Pancreatitis, Chronic (1) · Renal Insufficiency (1) · Renal Insufficiency, Chronic (1) · Short Bowel Syndrome (1) · Steatorrhea (1)
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (1) · London North West Healthcare NHS Trust (1) · Seven Oaks Hospital Chronic Disease Innovation Centre (1) · Texas A&M University (1) · Texas Christian University (1) · University Hospital, Basel, Switzerland (1) · University of Dublin, Trinity College (1) · University of Florida (1) · University of Wisconsin, Madison (1) · Vanderbilt University (1) · Yale University (1)
United States (5) · Canada (1) · Ireland (1) · Switzerland (1)
Chad R Ritch, MD (1) · Christoph Beglinger, MD (1) · Gina J Hill, PhD (1) · Heidi J Silver, PhD, RD (1) · Jeffrey Testani, MD (1) · Kevin P Fennelly, MD, MPH (1) · Laura A Healy, BSc RD (1) · Michael S Cookson, MD (1) · Nicolaas EP Deutz, MD, PhD (1) · Peter E Clark, MD (1) · Sam S Chang, MD (1) · Scott Reeder, MD, PhD (1) · Sherry Simon, BS (1)
PMID 19247018, PMID 24268783, PMID 24582673, PMID 28742713
R01DK125783 (1)