4 completed, 1 enrolling by invitation, 1 not yet recruiting. 6 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 4, Enrolling by invitation 1, Not yet recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Endotoxin: new trials by email Literature Review of Endotoxin trials Research Report on Endotoxin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Endotoxin Exposure to Examine the Role of Inflammation in Alcohol Use Endotoxin, Placebo saline - Alcohol Use Disorder, Inflammatory Response | Phase 2 | Not yet recruiting | University of California, Los Angeles | 64 | 2026-09-01 | 2026-08-28 |
| Effect of Endotoxin on Alcohol Consumption Endotoxin - Alcohol Use Disorder | Phase 2 | Completed | Yale University | 27 | 2022-02-27 | 2025-11-03 |
| An Inflammatory Challenge Using Endotoxin Placebo, Endotoxin - Alcohol Use Disorder, Inflammatory Response | Phase 2 | Completed | University of California, Los Angeles | 20 | 2021-10-19 | 2025-05-01 |
| The Innate Central Nervous System Immune Response to an Experimental Immune Challenge in People With Fibromyalgia Endotoxin, Escherichia Coli, Magnetic Resonance Spectroscopy - Fibromyalgia | Phase 2 / Phase 3 | Completed | University of Alabama at Birmingham | 36 | 2020-03-11 | 2023-04-14 |
| Effects of Bronchial Segmental Endotoxin Instillation in Humans Saline, Endotoxin - Acute Lung Inflammation | Phase 2 | Enrolling by invitation | National Institutes of Health Clinical Center (CC) | 58 | 2015-06-18 | 2026-10-16 |
| Wilm's Tumor 1 Protein Vaccine to Treat Cancers of the Blood WT1 Peptide-Pulsed Dendritic Cells, Donor Lymphocytes, IL-4 - Leukemia, Acute Myelogenous (AML), Leukemia, Acute Lymphocytic (ALL) | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 10 | 2008-02-22 | 2017-04-12 |
Alcoholism (3) · Chronic Pain (1) · Consciousness Disorders (1) · Fibromyalgia (1) · Hematologic Neoplasms (1) · Hodgkin Disease (1) · Leukemia (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Leukemia, Myeloid, Acute (1) · Lymphoma, Non-Hodgkin (1) · Myelodysplastic Syndromes (1) · Neuroinflammatory Diseases (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1)
University of California, Los Angeles (2) · National Cancer Institute (NCI) (1) · National Institutes of Health Clinical Center (CC) (1) · University of Alabama at Birmingham (1) · Yale University (1)
United States (5)
Lara Ray, PhD (2) · Anthony F Suffredini, M.D. (1) · Jarred M Younger, PhD (1) · Terril Verplaetse, PhD (1) · Terry J Fry, M.D. (1)
K24AA025704 (1), R03AA028361 (1)