4 completed, 4 recruiting, 4 unknown, 1 not yet recruiting. 7 Phase 4, 4 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 7 | Recruiting 4, Completed 1, Not yet recruiting 1, Unknown 1 |
| Not applicable | 4 | Completed 2, Terminated 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow DAPT: new trials by email Literature Review of DAPT trials Research Report on DAPT
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rivaroxaban for Slow Coronary Flow After PCI in STEMI Dual Antiplatelet (DAPT) Therapy, Rivaroxaban - ST Elevation Myocardial Infarction, No-Reflow Phenomenon | Phase 4 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 60 | 2025-10-01 | 2025-09-29 |
| Lacunar Stroke hyperAcute Clinical Utilization of Novel Approach Regimens: Rt-PA vs. DAPT Randomised Clinical Trial rt-PA, DAPT - Lacunar Stroke, Stroke | Phase 4 | Recruiting | Nippon Medical School | 500 | 2025-08-01 | 2026-08-04 |
| Century Clot-Guided Prophylactic Rivaroxaban for Post STEMI Complicating Left Ventricular Thrombus NOAC+DAPT, DAPT - STEMI - ST Elevation Myocardial Infarction | Phase 4 | Recruiting | Zunyi Medical College | 374 | 2024-04-01 | 2024-03-19 |
| Antithrombotic Therapy After Coronary Artery Bypass Grafting Combined With Coronary Endarterectomy Warfarin, DAPT, CE+CABG - Anticoagulation, Coronary Endarterectomy | Phase 4 | Recruiting | China National Center for Cardiovascular Diseases | 202 | 2023-04-11 | 2025-11-18 |
| Sequential MonotherApy of TicagrElor and Clopidogrel After Coronary Intervention Standard-DAPT of Ticagrelor plus aspirin, Sequential monotherapy of Ticagrelor and clopidogrel - Acute Coronary Syndrome, Percutaneous Coronary Intervention | Phase 4 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2690 | 2023-03-28 | 2024-08-07 |
| Clinical Outcomes Between Anticoagulation and DAPT Therapy in AF Patients Successfully Undergoing LAAO Rivaroxaban, DAPT - Left Atrial Appendage Thrombosis, Thrombi | Phase 4 | Unknown | Shanghai Zhongshan Hospital | 826 | 2022-11-11 | 2022-11-15 |
| Acute Myocardial Infarction Study in Northeastern China thrombolysis - Acute Myocardial Infarction | Unknown | Second Hospital of Jilin University | 3159 | 2019-09-09 | 2020-06-30 | |
| Anticoagulant Versus Dual Antiplatelet Therapy for Preventing Leaflet Thrombosis and Cerebral Embolization After Transcatheter Aortic Valve Replacement NOAC, DAPT - Aortic Valve Stenosis | Phase 4 | Completed | Duk-Woo Park, MD | 235 | 2018-03-15 | 2021-11-08 |
| XIENCE 28 Global Study XIENCE, DAPT - Bleeding Disorder, Stroke, Ischemic | Not applicable | Completed | Abbott Medical Devices | 963 | 2018-02-09 | 2021-03-04 |
| Assessment of Dual Antiplatelet Therapy Versus Rivaroxaban In Atrial Fibrillation Patients Treated With Left Atrial Appendage Closure Rivaroxaban 10 mg qd, Rivaroxaban 15 mg qd, DAPT - Atrial Fibrillation, Atrial Appendage | Phase 2 / Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 105 | 2017-09-13 | 2021-12-21 |
| XIENCE 90: A Safety Evaluation of 3-month DAPT After XIENCE Implantation for HBR Patients. XIENCE, DAPT - Coronary Artery Lesions | Not applicable | Completed | Abbott Medical Devices | 2047 | 2017-07-19 | 2021-11-05 |
| Xience Versus Synergy in Left Main PCI Percutaneous coronary intervention, Dual antiplatelet therapy - Coronary Artery Disease | Not applicable | Unknown | NHS National Waiting Times Centre Board | 818 | 2014-12-01 | 2014-12-01 |
| COBRA SHIELD OCT Study Aspirin, Resolute Integrity DES, COBRA PzF - Stable Angina | Not applicable | Terminated | CeloNova BioSciences, Inc. | 8 | 2014-06-01 | 2020-10-06 |
| CardiOvascular Risk and idEntificAtion of Potential High-risk Population in Acute Myocardial Infarction II (COREA-AMI II) Percutaneous coronary intervention, Dual-antiplatelet therapy - Acute Myocardial Infarction, Percutaneous Coronary Intervention | Unknown | Seoul St. Mary's Hospital | 13000 | 2004-01-01 | 2016-07-06 |
Coronary Artery Disease (2) · Hemorrhage (2) · Ischemic Stroke (2) · ST Elevation Myocardial Infarction (2) · Stroke (2) · Acute Coronary Syndrome (1) · Anemia (1) · Angina, Stable (1) · Aortic Valve Stenosis (1) · Atrial Fibrillation (1) · Hematologic Diseases (1) · Hemorrhagic Stroke (1) · Hemostatic Disorders (1) · No-Reflow Phenomenon (1) · Renal Insufficiency (1)
Abbott Medical Devices (2) · Second Affiliated Hospital, Zhejiang University, School of Medicine (2) · Assistance Publique - Hôpitaux de Paris (1) · CeloNova BioSciences, Inc. (1) · China National Center for Cardiovascular Diseases (1) · Duk-Woo Park, MD (1) · NHS National Waiting Times Centre Board (1) · Nippon Medical School (1) · Second Hospital of Jilin University (1) · Seoul St. Mary's Hospital (1) · Shanghai Zhongshan Hospital (1) · Zunyi Medical College (1)
China (6) · Hong Kong (2) · South Korea (2) · Taiwan (2) · Austria (1) · Belgium (1) · Finland (1) · France (1) · Germany (1) · Italy (1) · Japan (1) · Netherlands (1) · Portugal (1) · Singapore (1) · Spain (1)
Bin Liu, Ph.D (1) · Cai De Jin, MD (1) · Jun Jiang, Doctor (1) · Kiyuk Chang, MD, PhD (1) · Marco Valgimigli, MD (1) · Pasi Karjalainen, MD, PhD (1) · Roxana Mehran (1) · Seung-jung Park, MD (1) · Yong Sun, MD (1) · Youngkeun Ahn, MD, PhD (1) · Yuki Sakamoto (1)
PMID 33031789, PMID 34794687, PMID 19717846, PMID 19923168, PMID 25154978, PMID 25173339, PMID 26498666, PMID 27554803, PMID 29094604, PMID 29622168, PMID 29930021, PMID 30127210, PMID 30166073, PMID 32674675, PMID 33402409, PMID 34035090, PMID 34737035, PMID 35373583, PMID 36000434, PMID 36346059, PMID 37019077, PMID 37493020, PMID 37586823, PMID 38151311, PMID 38471483, PMID 38679500, PMID 39158557, PMID 40816554, PMID 41213699, PMID 41293617, PMID 41299333, PMID 41555573, PMID 42773911