11 completed, 3 recruiting, 3 terminated, 1 active not recruiting. 6 Not applicable, 4 Phase 3, 3 Phase 2, 3 Phase 4, 1 Phase 1.
Follow D: new trials by email Literature Review of D trials Research Report on D
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of Esketamine - Dexmedetomidine Combination Versus Dexmedetomidine Monotherapy for Hyperactive Delirium in ICU Patients on Non-Invasive Respiratory Support (SEED-NIRS Trial): Study Protocol of a Randomized Controlled Trial Esketamine combined with dexmedetomidine, Dexmedetomidine - Dexmedetomidine, Ketamine | Phase 4 | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 356 | 2026-09-28 | 2026-09-03 |
| Personalising Treatment for Myeloma Patients Based on Initial Response to NHS Treatment and Their Overall Fitness Level Daratumumab, Lenalidomide, Dexamethasone - Multiple Myeloma (MM), Plasma Cell Leukemia (PCL) | Phase 3 | Recruiting | University of Leeds | 1226 | 2026-07-01 | 2026-07-15 |
| A Study in Participants With Relapsed or Refractory Multiple Myeloma for IBI3003 Pomalidomide Capsules, Bortezomib for Injection, Daratumumab Injection (Subcutaneous Injection) - Relapsed or Refractory Multiple Myeloma | Phase 3 | Recruiting | Innovent Biologics (Suzhou) Co. Ltd. | 255 | 2026-06-11 | 2026-09-17 |
| Effects of Staged Adapted Inclusions in Infant Cereals on Oral-motors Patterns of 6-24 Month-old Children A, B, C - Healthy, Infant and Young Child Feeding | Not applicable | Recruiting | Société des Produits Nestlé (SPN) | 153 | 2025-11-05 | 2026-01-06 |
| Innovating Shorter, All- Oral, Precised Treatment Regimen for Rifampicin Resistant Tuberculosis：BDLL Chinese Cohort bedaquiline, delamanid, linezolid - Drug-resistant Tuberculosis, Pulmonary Tuberculosis | Phase 3 | Active not recruiting | Huashan Hospital | 120 | 2024-11-27 | 2025-09-02 |
| Low-dose Droperidol for Prevention of Postoperative Delirium in Elderly Patients After Non-cardiac Surgery Droperidol Injection, Saline - Digestive System Disease, Urologic Diseases | Not applicable | Terminated | RenJi Hospital | 797 | 2022-11-21 | 2026-08-12 |
| SVRd for the Treatment of Newly Diagnosed Multiple Myeloma Patients Presenting With Extramedullary Disease Selinexor, Bortezomib, Lenalidomide - Multiple Myeloma | Phase 2 | Completed | The First Affiliated Hospital with Nanjing Medical University | 29 | 2022-07-15 | 2026-09-02 |
| Efficacy and Safety of Dexketoprofen/Vitamin B Vs Dexketoprofen for Post-traumatic Cervical Sprain Grade I-II Dexketoprofen/Vitamin B, Dexketoprofen - Acute Low Back Pain | Phase 3 | Completed | Laboratorios Silanes S.A. de C.V. | 174 | 2021-11-23 | 2024-11-13 |
| Infusional Fluorouracil and Weekly Docetaxel for Gastric Cancer With Bone Marrow Involvement and DIC 5-fluorouracil, Docetaxel - Gastric Cancer, Bone Marrow Metastasis | Phase 2 | Completed | Sixth Affiliated Hospital, Sun Yat-sen University | 24 | 2021-01-15 | 2024-03-25 |
| Lidocaine Versus Duloxetine for the Prevention of Taxane-Induced Peripheral Neuropathy In Breast Cancer Patients Lidocaine in Saline, Duloxetine 30 MG, Normal saline - Peripheral Neuropathy, Chemotherapy-induced Peripheral Neuropathy | Not applicable | Completed | Gamal Mohamed Taha Abouelmagd | 60 | 2021-01-15 | 2022-07-11 |
| A Randomised, Cross-over, Relative Bioavailability Study of Nicotine Delivery and Nicotine Extraction From Oral Products A, B, C - Healthy Volunteers | Not applicable | Completed | Imperial Brands PLC | 24 | 2020-07-01 | 2023-10-13 |
| Dosage of Epidural Morphine in Elderly Patients 1.5 mg of Morphine Sulfate, Normal saline, 3 mg of Morphine Sulfate - Age Problem, Abdominal Cancer | Phase 4 | Completed | Assiut University | 96 | 2020-03-20 | 2025-03-05 |
| The Effects of Pulsed Elelectro-Magnetic Fields ("PEMF") in the Treatment of Venous Stasis Leg Ulcers PEMF therapy with a high-power PEMF device, PEMF therapy with a medium PEMF power device, PEMF therapy with a low-power PEMF device - Venous Stasis Ulcers | Terminated | PEMF Systems, Inc. | 33 | 2018-11-08 | 2024-04-05 | |
| Novel Antidiabetic Medications and Their Effect on Liver Steatosis (NAMELS-18) Empagliflozin, Dulaglutide, Control Rx - Non-Alcoholic Fatty Liver Disease, Liver Steatosis | Completed | National and Kapodistrian University of Athens | 78 | 2018-06-01 | 2023-07-14 | |
| Vitamin D Supplementation in Physical Performance vitamin D supplement, Placebo - Healthy, Athletes | Not applicable | Completed | National Nutrition and Food Technology Institute | 70 | 2017-03-01 | 2017-10-30 |
| Intensity-modulated Radiotherapy With Integrated-boost in Patients With Spinal Bone Metastases A, B, C - Vertebral Bony Metastases | Phase 2 | Unknown | Heidelberg University | 120 | 2016-09-01 | 2016-07-14 |
| Sore Throat Prevention Following Intubation xylocaine, Dexamethasone, Xylocaine and Dexamethasone - Sore Throat | Phase 4 | Completed | University of Jordan | 300 | 2015-11-01 | 2016-02-15 |
| Treatment of BV With Donaxyl and a Molecular Test of Cure D - Bacterial Vaginoses | Completed | Skaraborg Hospital | 58 | 2015-05-01 | 2019-08-15 | |
| Healthy Volunteer Pilot Study Using 3 Types of Modified Release Formulations of Firategrast to Investigate How Quickly Absorption From the Digestive System Takes Place. A, B, C - Multiple Sclerosis, Relapsing-Remitting | Phase 1 | Completed | GlaxoSmithKline | 20 | 2010-04-19 | 2017-06-20 |
| The Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes Group A Intravenous bolus of 1000 ml lactated ringers solution, Group B Intravenous bolus bolus 1000 ml lactated ringers solution oxytocin decrease to 1/2 current rate, Group C 125 mL/hr of lactated ringers - Pregnancy, Labor Pain | Not applicable | Terminated | Northwestern University | 251 | 2007-09-01 | 2022-01-13 |
Multiple Myeloma (3) · Agnosia (1) · Breast Neoplasms (1) · Digestive System Diseases (1) · Disseminated Intravascular Coagulation (1) · Emergence Delirium (1) · Fatty Liver (1) · Frailty (1) · Genital Diseases, Female (1) · Labor Pain (1) · Leg Ulcer (1) · Leukemia, Plasma Cell (1) · Multiple Sclerosis, Relapsing-Remitting (1) · Neoplasms, Plasma Cell (1) · Non-alcoholic Fatty Liver Disease (1)
The First Affiliated Hospital with Nanjing Medical University (2) · Assiut University (1) · Gamal Mohamed Taha Abouelmagd (1) · GlaxoSmithKline (1) · Heidelberg University (1) · Huashan Hospital (1) · Imperial Brands PLC (1) · Innovent Biologics (Suzhou) Co. Ltd. (1) · Laboratorios Silanes S.A. de C.V. (1) · National Nutrition and Food Technology Institute (1) · National and Kapodistrian University of Athens (1) · Northwestern University (1) · PEMF Systems, Inc. (1) · RenJi Hospital (1) · Sixth Affiliated Hospital, Sun Yat-sen University (1)
China (6) · Egypt (2) · United States (2) · Australia (1) · Germany (1) · Greece (1) · Iran (1) · Mexico (1) · Spain (1) · Sweden (1) · United Kingdom (1)
Aamir Siddiqui, MD (1) · Aboud Aljabari (1) · Adelfia Urenda Quezada, M.D (1) · Charlotte Pawlyn (1) · Diab Hetta, MD (1) · Diansan Su, MD,PHD (1) · Gordon Cook (1) · Guillemette Epailly, BS, MArch (1) · Jian Xiao, MD (1) · Juan B Alcocer Herrera, M.D (1) · Lijuan Chen (1)
PMID 1338829, PMID 22172095, PMID 23052695, PMID 23101946, PMID 24494204, PMID 24890347, PMID 29357902, PMID 35732751, PMID 36346044, PMID 37774185, PMID 38842764, PMID 41564431, PMID 7982015, PMID 8139189