21 completed, 9 unknown, 5 terminated, 4 withdrawn. 22 Not applicable, 13 Phase 2, 3 Phase 1, 1 Early Phase 1, 1 Phase 3.
Follow Cyberknife: new trials by email Literature Review of Cyberknife trials Research Report on Cyberknife
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety of Cyberknife in Patients With Borderline Resectable or Locally Advanced Pancreatic Adenocarcinoma Cyberknife - Pancreas Adenocarcinoma | Not applicable | Recruiting | Capital Health System, Inc | 10 | 2021-06-22 | 2023-03-31 |
| Immunotherapy SBRT Sensitization of the Programmed Death-1 (PD-1) Effect Stereotactic Body Radiotherapy - Metastatic Nonsmall Cell Lung Cancer, Non Small Cell Lung Cancer | Phase 2 | Completed | Crozer-Keystone Health System | 3 | 2017-04-28 | 2023-03-06 |
| Stereotactic Body Radiation Therapy (SBRT) for Prostate Cancer Stereotactic Body Radiation Therapy (SBRT) radiation for prostate cancer utilizing the Elekta Versa or Agility System. - Prostate Cancer | Not applicable | Active not recruiting | Hoag Memorial Hospital Presbyterian | 100 | 2016-10-21 | 2025-09-15 |
| Phase ǀ Study on Pancreatic Cancer Treated by CyberKnife CyberKnife - Pancreatic Tumor | Not applicable | Completed | Changhai Hospital | 16 | 2016-03-01 | 2021-05-14 |
| Stereotactic Radiosurgery for Soft Tissue Sarcoma CyberKnife - Soft Tissue Sarcoma | Not applicable | Withdrawn | The Cooper Health System | 2015-06-01 | 2024-03-15 | |
| Focused Stereotactic Radiation Treatment of Prostatic Adenocarcinoma Cyberknife - Prostate Cancer | Unknown | Centre Francois Baclesse, Luxembourg | 26 | 2015-01-01 | 2022-06-22 | |
| An Effectiveness and Toxicity of CyberKnife Based Radiosurgery for Parkinson Disease Radiosurgical thalamotomy, CyberKnife - Parkinson Disease | Phase 2 | Unknown | Maria Sklodowska-Curie National Research Institute of Oncology | 27 | 2015-01-01 | 2015-04-02 |
| Study To Establish Maximum Tolerated Dose (MTD) of Cyberknife in Patients With Un-Resectable Pancreas Cancer (TL002) Gemcitabine, nab-paclitaxel, CyberKnife - Pancreas Cancer, Pancreatic Cancer | Phase 1 | Terminated | The Cooper Health System | 30 | 2015-01-01 | 2019-07-30 |
| Study on Effectiveness and Safety of Hepatocellular Carcinoma Patients Treated With CyberKnife CyberKnife - Liver Neoplasms | Phase 2 | Unknown | Tianjin Medical University Cancer Institute and Hospital | 117 | 2014-05-01 | 2016-10-07 |
| Feasibility Study of Stereotactic Body Radiotherapy for Early Breast Cancer Stereotactic body radiotherapy (SBRT) - Breast Neoplasm | Phase 1 | Unknown | Juravinski Cancer Center | 32 | 2014-02-01 | 2015-03-31 |
| CyberKnife® as Monotherapy or Boost SBRT for Intermediate or High Risk Localized Prostate Cancer CyberKnife, Androgen Deprivation Therapy (ADT), Intensity Modulated radiation therapy (IMRT) - Prostate Adenocarcinoma | Not applicable | Completed | Wake Forest University Health Sciences | 83 | 2013-11-19 | 2024-10-03 |
| Evaluation of Low-dose Irinotecan and Cyberknife® SBRT to Treat Colorectal Cancer With Limited Liver Metastasis Irinotecan, CyberKnife - Colorectal Cancer | Not applicable | Withdrawn | Wake Forest University Health Sciences | 2013-10-01 | 2024-10-04 | |
| Fractionated Stereotactic Radiosurgery for Large Brain Metastases Fractionated Stereotactic Radiosurgery - Large Brain Mets | Not applicable | Completed | Steven Burton | 20 | 2013-07-16 | 2025-05-28 |
| SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN SBRT, Cetuximab, Docetaxel - Previously-Irradiated, Squamous Cell Carcinoma of the Head and Neck Cancer | Phase 2 | Completed | Heath Skinner | 40 | 2013-07-03 | 2023-06-05 |
| A Phase II Study of Cyberknife Radiosurgery for Renal Cell Carcinoma CyberKnife - Renal Cell Carcinoma | Not applicable | Unknown | Beth Israel Deaconess Medical Center | 46 | 2013-07-01 | 2024-08-15 |
| Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation Stereotactic Radiosurgery (SRS), Chemotherapy - Oligometastatic Disease | Phase 2 | Terminated | Steven Burton | 24 | 2013-06-07 | 2023-10-11 |
| The SPARC Trial: Stereotactic Prostate Ablative Radiotherapy Using Cyberknife Radiotherapy - Prostate Cancer | Phase 2 | Unknown | Royal Marsden NHS Foundation Trust | 20 | 2013-06-01 | 2014-05-23 |
| SBRT for Close or Positive Margins After Resection of Pancreatic Adenocarcinoma Stereotactic Body Radiation Therapy (SBRT) - Adenocarcinoma of the Pancreas | Not applicable | Completed | David A. Clump, MD, PhD | 50 | 2013-02-06 | 2021-11-24 |
| A Study of Pre-Operative Cyberknife in Patients With Potentially Resectable Pancreas Cancer Gemcitabine, Stereotactic Radiosurgery - Pancreas Cancer, Pancreatic Cancer | Early Phase 1 | Unknown | The Cooper Health System | 15 | 2013-01-01 | 2016-03-14 |
| Stereotactic Radiosurgery or Other Local Ablation Then Erlotinib in Epidermal Growth Factor Receptor (EGFR) Stereotactic Radiosurgery, Erlotinib - Non Small Cell Lung Cancer | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 32 | 2012-12-11 | 2021-01-12 |
Showing 20 of 41. Sign in to see all of them.
Prostatic Neoplasms (8) · Carcinoma, Non-Small-Cell Lung (5) · Pancreatic Neoplasms (5) · Carcinoma, Hepatocellular (4) · Liver Neoplasms (4) · Lung Neoplasms (3) · Breast Neoplasms (2) · Colorectal Neoplasms (2) · Head and Neck Neoplasms (2) · Snyder Robinson syndrome (2) · Adrenal Gland Neoplasms (1) · Bone Neoplasms (1) · Brain Neoplasms (1) · Carcinoma, Renal Cell (1) · Colonic Neoplasms (1)
Accuray Incorporated (3) · Beth Israel Deaconess Medical Center (3) · Steven Burton (3) · The Cooper Health System (3) · Wake Forest University Health Sciences (3) · Community Cancer Center, Normal, Illinois (2) · David A. Clump, MD, PhD (2) · Stanford University (2) · UNC Lineberger Comprehensive Cancer Center (2) · Adam Olson (1) · Albert Koong (1) · Boston Medical Center (1) · Capital Health System, Inc (1) · Centre Francois Baclesse, Luxembourg (1) · Centre Oscar Lambret (1)
United States (33) · China (3) · United Kingdom (2) · Canada (1) · France (1) · Luxembourg (1) · Poland (1)
David A Clump, MD (3) · Anand Mahadevan, MD (2) · Arica Hirsch, MD (2) · Shermian Woodhouse, MD (2) · Steve Burton, MD (2) · Adam Olson, MD (1) · Albert Koong (1) · Andrew Gaya (1) · Aya Kamaya (1) · Billy W Loo, Jr, MD, PhD (1) · Do-Hoon Kim, BASc, MD, MSc, FRCPC (1) · Donald B Fuller, MD (1) · Dwight E Heron, MD (1) · Edward S James, M.D. (1) · George Mardirossian, PhD (1)
PMID 12192016, PMID 12393820, PMID 16360786, PMID 28069017, PMID 2990668, PMID 30003996, PMID 30191864, PMID 34405577, PMID 35387414