7 completed, 4 unknown, 2 terminated. 13 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 13 | Completed 7, Unknown 4, Terminated 2 |
| Phase 1 | 1 | Terminated 1 |
Follow CyberKnife: new trials by email Literature Review of CyberKnife trials Research Report on CyberKnife
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Immunotherapy SBRT Sensitization of the Programmed Death-1 (PD-1) Effect Stereotactic Body Radiotherapy - Metastatic Nonsmall Cell Lung Cancer, Non Small Cell Lung Cancer | Phase 2 | Completed | Crozer-Keystone Health System | 3 | 2017-04-28 | 2023-03-06 |
| An Effectiveness and Toxicity of CyberKnife Based Radiosurgery for Parkinson Disease Radiosurgical thalamotomy, CyberKnife - Parkinson Disease | Phase 2 | Unknown | Maria Sklodowska-Curie National Research Institute of Oncology | 27 | 2015-01-01 | 2015-04-02 |
| Study on Effectiveness and Safety of Hepatocellular Carcinoma Patients Treated With CyberKnife CyberKnife - Liver Neoplasms | Phase 2 | Unknown | Tianjin Medical University Cancer Institute and Hospital | 117 | 2014-05-01 | 2016-10-07 |
| SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN SBRT, Cetuximab, Docetaxel - Previously-Irradiated, Squamous Cell Carcinoma of the Head and Neck Cancer | Phase 2 | Completed | Heath Skinner | 40 | 2013-07-03 | 2023-06-05 |
| Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation Stereotactic Radiosurgery (SRS), Chemotherapy - Oligometastatic Disease | Phase 2 | Terminated | Steven Burton | 24 | 2013-06-07 | 2023-10-11 |
| The SPARC Trial: Stereotactic Prostate Ablative Radiotherapy Using Cyberknife Radiotherapy - Prostate Cancer | Phase 2 | Unknown | Royal Marsden NHS Foundation Trust | 20 | 2013-06-01 | 2014-05-23 |
| Stereotactic Radiosurgery or Other Local Ablation Then Erlotinib in Epidermal Growth Factor Receptor (EGFR) Stereotactic Radiosurgery, Erlotinib - Non Small Cell Lung Cancer | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 32 | 2012-12-11 | 2021-01-12 |
| A Study of IMM-101 in Combination With Radiation Induced Tumour Necrosis in Colorectal Cancer Mycobacterium obuense, SBRT - Metastatic Colorectal Cancer | Phase 2 | Completed | Immodulon Therapeutics Ltd | 12 | 2012-05-30 | 2024-11-25 |
| Gemcitabine/Capecitabine Followed by SBRT in Pancreatic Adenocarcinoma Gemcitabine, Capecitabine, Stereotactic Body Radiation Therapy (SBRT) - Pancreatic Cancer | Phase 2 | Completed | David A. Clump, MD, PhD | 35 | 2011-07-25 | 2022-03-08 |
| Stereotaxic Irradiation of Hepatocellular Carcinoma Fiducials, CyberKnife - Hepatocellular Carcinoma | Phase 2 | Completed | Centre Oscar Lambret | 44 | 2009-08-31 | 2026-03-13 |
| Radiosurgery for Glioblastoma Multiforme CyberKnife - Glioblastoma Multiforme | Phase 1 / Phase 2 | Terminated | Beth Israel Deaconess Medical Center | 4 | 2007-02-01 | 2017-03-06 |
| CyberKnife Radiosurgical Treatment of Inoperable Early Stage Non-Small Cell Lung Cancer CyberKnife Stereotactic Radiosurgery - Non-small Cell Lung Cancer | Phase 2 | Unknown | Accuray Incorporated | 40 | 2006-04-01 | 2021-03-05 |
| Short Course of Radiation for Gliomas in Elderly Patients CyberKnife - High Grade Gliomas | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 26 | 2006-04-01 | 2017-01-27 |
Carcinoma, Non-Small-Cell Lung (3) · Liver Neoplasms (2) · Carcinoma, Hepatocellular (1) · Colorectal Neoplasms (1) · Glioblastoma (1) · Head and Neck Neoplasms (1) · Lung Neoplasms (1) · Pancreatic Neoplasms (1) · Parkinson Disease (1) · Prostatic Neoplasms (1) · Snyder Robinson syndrome (1) · Tremor (1)
Beth Israel Deaconess Medical Center (2) · Accuray Incorporated (1) · Centre Oscar Lambret (1) · Crozer-Keystone Health System (1) · David A. Clump, MD, PhD (1) · Heath Skinner (1) · Immodulon Therapeutics Ltd (1) · Maria Sklodowska-Curie National Research Institute of Oncology (1) · Royal Marsden NHS Foundation Trust (1) · Steven Burton (1) · Tianjin Medical University Cancer Institute and Hospital (1) · UNC Lineberger Comprehensive Cancer Center (1)
United States (8) · China (2) · United Kingdom (2) · France (1) · Poland (1)
Anand Mahadevan, MD (2) · David A Clump, MD (2) · Andrew Gaya (1) · James Luketich, MD (1) · Jared Weiss, MD (1) · Leszek Miszczyk, MD, PhD (1) · Steve J Burton, MD (1)