8 completed, 2 active not recruiting, 2 terminated, 1 recruiting. 15 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 15 | Completed 8, Active not recruiting 2, Terminated 2, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
Follow Cryotherapy: new trials by email Literature Review of Cryotherapy trials Research Report on Cryotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cryoablation and Arterial Infusion of SD-101 in Combination With Durvalumab and Tremelimumab SD-101, Cryotherapy, Tremelimumab - Hepatocellular Carcinoma | Phase 1 | Active not recruiting | University of California, San Diego | 16 | 2025-01-03 | 2026-07-28 |
| A Randomized Controlled Trial to Evaluate the Effectiveness of Bleomycin and Cryotherapy in Treating Plantar Warts. Bleomycin injection, Cryotherapy - Verruca Plantaris | Phase 1 / Phase 2 | Recruiting | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 70 | 2024-12-25 | 2025-03-24 |
| Comparisom of Liquid Nitrogen and Vitamin D3 in The Treatment of Cutaneous Warts liq nitrogen, intralesional vitamin D3 - Cutaneous Warts | Phase 1 | Completed | Combined Military Hospital Abbottabad | 60 | 2022-05-11 | 2023-02-22 |
| Effect of Cryotherapy Versus Post-operative Ibuprofen Medication on Post-operative Pain in Mandibular Molar Teeth With Symptomatic Irreversible Pulpitis cold saline (cryotherapy), Ibuprofen 400 mg, Final irrigation with normal saline - Symptomatic Irreversible Pulpitis | Phase 1 | Unknown | Cairo University | 36 | 2022-04-01 | 2022-04-22 |
| Comparative Study Between Treatment With Cryotherapy Alone Versus Cryotherapy Plus Salicylic Acid Dressing for Planter Warts Cryotherapy Alone, Cryotherapy plus Salicylic Acid - Plantar Wart | Phase 1 | Completed | Combined Military Hospital Abbottabad | 70 | 2022-03-01 | 2022-10-20 |
| Evaluation of Post-operative Pain and Expression of IL-8 Using Ketolac or Cryoirrigation as a Final Flush in Single Visit Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis and Apical Periodontitis.Randomized Clinical Trial. Ketorolac Tromethamine, Cryotherapy, Saline - Post-operative Pain | Phase 1 | Completed | Cairo University | 48 | 2021-09-01 | 2024-09-19 |
| Cryotherapy for Locally Advanced Esophageal Cancer Cryotherapy - Esophageal Cancer | Phase 1 | Active not recruiting | Hunter Holmes Mcguire Veteran Affairs Medical Center | 14 | 2020-02-11 | 2026-09-18 |
| Cryotherapy With in Situ Immunotherapy in Melanoma Metastasis Nivolumab 10 MG/ML Intravenous Solution [OPDIVO], Cryotherapy, Ipilimumab Injection - Melanoma (Skin) | Phase 1 / Phase 2 | Completed | University Hospital, Strasbourg, France | 19 | 2019-08-16 | 2026-06-05 |
| Intravitreal Carboplatin for the Treatment of Participants With Recurrent or Refractory Intraocular Retinoblastoma Carboplatin, Maxitrol®, Focal Therapy - Retinoblastoma | Phase 1 | Completed | St. Jude Children's Research Hospital | 8 | 2016-11-01 | 2020-02-20 |
| The Immuno-Response to Primary Cryotherapy for the Treatment of Prostate Cancer cryotherapy, sargramostim - Recurrent Prostate Cancer, Stage I Prostate Cancer | Phase 1 | Completed | University of Colorado, Denver | 19 | 2015-10-05 | 2022-02-09 |
| Safety and Efficacy of Cryoablation Combined With Radiation Therapy for the Palliation of Painful Bone Metastases Cryoablation, Radiation - Pain, Neoplasm Metastasis | Phase 1 | Withdrawn | Boston Scientific Corporation | 2013-04-01 | 2021-07-16 | |
| Safety and Efficacy of Cryoablation for the Palliation of Painful Bone Metastases Cryoablation - Pain, Neoplasm Metastasis | Phase 1 | Completed | Boston Scientific Corporation | 29 | 2011-11-01 | 2021-07-16 |
| Safety and Efficacy of Cryoablation for Abdominal Pain Associated With Pancreatic Cancer Cryoablation - Pain, Pancreatic Cancer | Phase 1 | Terminated | Boston Scientific Corporation | 14 | 2011-08-01 | 2021-07-16 |
| Knee Joint Icing and Knee-extension Strength Thermotherapy - Arthroplasty | Phase 1 | Terminated | Hvidovre University Hospital | 20 | 2010-04-01 | 2012-07-19 |
| Cryotherapy in Treating Patients With Primary Stage I Non-Small Cell Lung Cancer or Lung Metastasis Cryotherapy (PTC), Prednisone - Lung Cancer, Metastatic Cancer | Phase 1 | Completed | Barbara Ann Karmanos Cancer Institute | 9 | 2009-03-01 | 2022-11-01 |
Neoplasm Metastasis (3) · Pain (3) · Bone Neoplasms (2) · Abdominal Pain (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Esophageal Neoplasms (1) · Lung Neoplasms (1) · Melanoma (1) · Pain, Postoperative (1) · Pancreatic Neoplasms (1) · Prostatic Neoplasms (1) · Retinoblastoma (1)
Boston Scientific Corporation (3) · Cairo University (2) · Combined Military Hospital Abbottabad (2) · Barbara Ann Karmanos Cancer Institute (1) · Hunter Holmes Mcguire Veteran Affairs Medical Center (1) · Hvidovre University Hospital (1) · St. Jude Children's Research Hospital (1) · The Fourth Affiliated Hospital of Zhejiang University School of Medicine (1) · University Hospital, Strasbourg, France (1) · University of California, San Diego (1) · University of Colorado, Denver (1)
United States (7) · France (2) · Pakistan (2) · Canada (1) · China (1) · Denmark (1) · Egypt (1)
Jerry Matteo, MD (2) · Adam Burgoyne, MD, PhD (1) · Al Barqawi (1) · Bente Holm, MSc (1) · David D Childs, MD (1) · Frank A. Baciewicz, MD (1) · Rachel Brennan, MD (1) · Tilak Shah, MD (1)
2018 (1), P30CA022453 (1)