13 completed, 6 terminated, 5 recruiting, 4 withdrawn. 36 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 36 | Completed 13, Terminated 6, Recruiting 5, Withdrawn 4, Not yet recruiting 3, Unknown 3, Active not recruiting 1, Enrolling by invitation 1 |
Follow corticosteroid: new trials by email Literature Review of corticosteroid trials Research Report on corticosteroid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Methylprednisolone Addition to Multimodal Pain Regimens After Anterior Cruciate Ligament Reconstruction Methyl Prednisolone (MP), Standard Post-Operative Pain Control, Surgeon's Standard ACL Postoperative Regimen - ACL Reconstruction | Phase 4 | Not yet recruiting | University of Alabama at Birmingham | 64 | 2026-09-01 | 2026-05-26 |
| PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis LUPKYNIS, belimumab, obinutuzumab or anifrolumab, mycophenolic acid analog (MPAA) - Lupus Nephritis | Phase 4 | Recruiting | Aurinia Pharmaceuticals Inc. | 150 | 2026-04-22 | 2026-08-03 |
| PPP Versus Corticosteroid for Thigh Muscle Injuries Corticosteroid, Platelet Poor Plasma - Thigh Muscle Injury, Thigh Injury | Phase 4 | Enrolling by invitation | Andrews Research & Education Foundation | 30 | 2026-03-25 | 2026-10-29 |
| Comparative Effectiveness of Upadacitinib vs Corticosteroids as First-Line Therapy for Acute Severe Ulcerative Colitis（UPFRONT） Upadacitinib, Corticosteroid - Acute Severe Ulcerative Colitis | Phase 4 | Recruiting | Yongquan Shi | 46 | 2026-03-23 | 2026-06-15 |
| Steroid Treatment for Severe Acute Respiratory Infection (STAR) Trial Corticosteroid - Hypoxemia, Severe Acute Respiratory Syndrome | Phase 4 | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 3000 | 2026-03-01 | 2026-02-19 |
| A Study Of Corticosteroid On Postoperative Pain After Ureteroscopy For Urinary Calculi Corticosteroid, Placebo - Ureteroscopy, Post Operative Pain | Phase 4 | Recruiting | Mayo Clinic | 90 | 2026-01-23 | 2026-02-03 |
| Intra-articular Infiltration of Platelet-Rich Fibrin vs Corticosteroid in Mild to Moderate Knee Osteoarthritis Platelet-rich fibrin (PRF), Corticosteroid - Gonarthrosis; Primary | Phase 4 | Not yet recruiting | Federal University of São Paulo | 90 | 2025-06-01 | 2025-04-02 |
| Multicentre Clinical Study to Evaluate the Effect of Personalized Therapy on Patients With Immunoglobulin A Nephropathy. Corticosteroid, Renin-angiotensin sytem blockers, Sodium-glucose cotransporter 2 inhibitor - Glomerulonephritis, Immunoglobulin A Nephropathy | Phase 4 | Recruiting | Fondazione Schena | 878 | 2023-05-01 | 2025-04-02 |
| A Study to Determine the Safety and Effectiveness of a Connective Tissue Allograft (ActiveMatrix) Verses Standard of Care in Adhesive Capsulitis of the Shoulder Corticosteroid, ActiveMatrix, Lidocaine - Adhesive Capsulitis | Phase 4 | Completed | The University of Texas Health Science Center, Houston | 56 | 2023-01-03 | 2026-03-05 |
| Effect of PRP vs Corticosteroid in Rotator Cuff Tendinopathy Subtypes in Arthroscopic Repair platelet rich plasma, Corticosteroid, Normal saline - Tendinopathy | Phase 4 | Active not recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 387 | 2022-12-15 | 2026-02-09 |
| Cytokine Guided Risk Stratification and Treatment in Pediatric Hemophagocytic Lymphohistiocytosis Dexamethasone, Etoposide, Ruxolitinib - Hemophagocytic Lymphohistiocytoses, Cytokine Storm | Phase 4 | Unknown | The Children's Hospital of Zhejiang University School of Medicine | 400 | 2022-09-01 | 2022-10-06 |
| Assessment and Comparison of Efficacy of Intra-Articular PRP and Corticosteroid in First CMC Joint OA Treatment PRP, Corticosteroid - Thumb Osteoarthritis, Hand Osteoarthritis | Phase 4 | Completed | Antalya Training and Research Hospital | 60 | 2022-02-01 | 2024-10-24 |
| Comparison Between Subacromial Ultrasound Guided and Systemic Steroid Injection for Frozen Shoulder Compound betamethasone Injection(Gluteal muscle injection), Compound betamethasone Injection(Subacromial Ultrasound Guided injection), Physical therapy - Frozen Shoulder, Shoulder Pain | Phase 4 | Terminated | Second Affiliated Hospital, Zhejiang University, School of Medicine | 20 | 2021-06-01 | 2023-12-29 |
| Once Weekly Infant Corticosteroid Trial for DMD Prednisolone - Duchenne Muscular Dystrophy | Phase 4 | Recruiting | Anne M. Connolly | 26 | 2021-04-30 | 2026-08-14 |
| High-Dose Corticosteroid or Tocilizumab for Clinical Worsening of COVID-19 Methylprednisolone, Tocilizumab - COVID-19 Virus Infection, Cytokine Storm | Phase 4 | Withdrawn | Marmara University | 2021-02-01 | 2021-11-24 | |
| Oral Akynzeo® vs Standard of Care in Preventing CINV in High-risk MEC Patients (MyRisk) NEPA (300mg netupitant/0.5mg palonosetron), Granisetron, 2 mg (oral) or 1 mg (IV) OR Palonosetron, 0.5 mg (oral), 0.25mg (IV) OR Ondansetron, 16 mg (oral) or 8 mg (IV) OR Dolasetron 100 mg (oral) OR Tropisetron 5 mg (oral or IV), Dexamethasone, 8 mg (oral) or equivalent IV dose - Chemotherapy-induced Nausea and Vomiting | Phase 4 | Completed | Helsinn Healthcare SA | 414 | 2021-02-01 | 2025-12-02 |
| Pilot Study: Effect of Dexamethasone vs Vicodin in Reducing Post-operative Pain Vicodin, Dexamethasone - Oral Surgery | Phase 4 | Withdrawn | Boston University | 2020-02-01 | 2019-11-13 | |
| Trial of Acquired Haemophilia With Steroid Combined With Cyclophosphamide Versus Steroid Combined With Rituximab Steroid, Rituximab, Cyclophosphamide - Acquired Hemophilia A | Phase 4 | Completed | Institute of Hematology & Blood Diseases Hospital, China | 66 | 2017-12-29 | 2026-02-11 |
| Dexamethasone and Post-tonsillectomy Pain in Children Dexamethasone, Placebo - Pediatric Post-tonsillectomy Pain | Phase 4 | Completed | Nationwide Children's Hospital | 137 | 2016-06-01 | 2020-09-10 |
| Efficacy and Safety of a Combination of Mycophenolate Mofetil and Corticosteroid in Advanced IgA Nephropathy Mycophenolate Mofetil, ACE inhibitor, Corticosteroid - IgA Nephropathy | Phase 4 | Unknown | Yonsei University | 100 | 2016-06-01 | 2016-12-05 |
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Bursitis (2) · Crohn Disease (2) · Cytokine Release Syndrome (2) · Dermatitis, Atopic (2) · Glomerulonephritis, IGA (2) · Osteoarthritis, Knee (2) · Pain (2) · Pain, Postoperative (2) · Temporomandibular Joint Disorders (2) · Agnosia (1) · Asthma (1) · COVID-19 (1) · Deglutition Disorders (1) · Dermatitis (1) · Esophageal Achalasia (1)
Astellas Pharma Korea, Inc. (2) · Mayo Clinic (2) · Second Affiliated Hospital, Zhejiang University, School of Medicine (2) · Andrews Research & Education Foundation (1) · Anne M. Connolly (1) · Antalya Training and Research Hospital (1) · Astellas Pharma Inc (1) · Aurinia Pharmaceuticals Inc. (1) · Boston University (1) · CHU de Quebec-Universite Laval (1) · EMS (1) · Emory University (1) · Federal University of São Paulo (1) · Fondazione Schena (1) · Helsinn Healthcare SA (1)
United States (15) · China (7) · South Korea (3) · Spain (2) · Brazil (1) · Czechia (1) · Germany (1) · Greece (1) · Italy (1) · Netherlands (1) · Switzerland (1) · Thailand (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Alex Molasiotis, prof. (1) · Amit Momaya, MD (1) · Anne Connolly, MD (1) · Brett J Kindle, M.D. (1) · Eric F Berkman, MD (1) · Francesco P Schena (1) · Gary F Bouloux, MD, DDS (1) · Gildasio DeOliveira, M.D. (1) · H.M. Schuller, PhD, MD (1) · Jane O'Halloran, MD, PhD (1) · Jean-Louis Stril, MD (1) · Julian Campo Trapero (1)
PMID 15851648, PMID 17533019, PMID 17978307, PMID 19571790, PMID 19571791, PMID 20398269, PMID 21111490, PMID 21606384, PMID 21669954, PMID 21852672, PMID 22463723, PMID 24029421, PMID 25018935, PMID 25048494, PMID 25585823, PMID 26598458, PMID 26630142, PMID 27632067, PMID 27632069, PMID 28341274, PMID 28763548, PMID 30177015, PMID 31603721, PMID 32409237, PMID 32609918, PMID 32889014, PMID 32970396, PMID 32998816, PMID 33023926, PMID 35935714, PMID 37772889, PMID 37851608, PMID 38299639, PMID 38770818, PMID 42639617, PMID 9100040
K23GM104354 (1)