9 completed, 3 recruiting, 1 enrolling by invitation, 1 terminated. 11 Not applicable, 3 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 6, Recruiting 3, Enrolling by invitation 1, Unknown 1 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 2 | Completed 2 |
Follow Cognitive Processing Therapy (CPT): new trials by email Literature Review of Cognitive Processing Therapy (CPT) trials Research Report on Cognitive Processing Therapy (CPT)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Developing and Testing Innovative Care Pathways for Screening and Treatment of OUD/PTSD in Jails Cognitive Processing Therapy (CPT), Written Exposure Therapy (WET) - Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms | Not applicable | Enrolling by invitation | University of Arkansas | 338 | 2026-01-20 | 2026-06-18 |
| Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD) Modular Cognitive Processing Therapy, Modular Prolonged Exposure Therapy, Step Down Treatment - Posttraumatic Stress Disorder, PTSD | Not applicable | Recruiting | The University of Texas Health Science Center at San Antonio | 302 | 2025-12-12 | 2025-12-19 |
| Exploring Efficacy of Multi-Mode Cognitive Processing Therapy (CPT) for PTSD Cognitive Processing Therapy (CPT), Treatment as Usual (TAU) - Posttraumatic Stress Disorder | Not applicable | Recruiting | Far Eastern Memorial Hospital | 60 | 2025-09-01 | 2026-09-03 |
| Enhancing PTSD Treatment Outcomes by Improving Patient-Provider Communication Adjunctive writing to amplify response and engagement (AWARE), Cognitive processing therapy (CPT), Prolonged exposure (PE) - Stress Disorders, Post-Traumatic | Not applicable | Recruiting | Boston University | 54 | 2025-01-15 | 2026-04-01 |
| Stellate Ganglion Block to Augment Trauma-focused Therapy Among Veterans With PTSD Cognitive Processing Therapy (CPT), Stellate Ganglion Block - PTSD, Trauma and Stressor Related Disorders | Phase 2 | Completed | Ohio State University | 85 | 2022-01-03 | 2025-07-03 |
| Improving Treatment Outcomes for Suicidal Veterans With PTSD Cognitive Processing Therapy (CPT), Crisis Response Plan (CRP), Safety Planning Intervention (SPI) - Suicidal Ideation, Suicide, Attempted | Not applicable | Completed | Ohio State University | 157 | 2021-01-15 | 2024-12-20 |
| Cognitive Processing Therapy in Syrian Women Exposed to IPV Cognitive Processing Therapy (CPT) - Depression, Anxiety | Not applicable | Completed | British University In Egypt | 30 | 2021-01-05 | 2023-01-06 |
| Network Dysregulation Among Individuals With Comorbid Tinnitus and PTSD Cognitive Processing Therapy (CPT) - Stress Disorders, Post-Traumatic, Tinnitus | Not applicable | Completed | The University of Texas Health Science Center at San Antonio | 10 | 2019-01-04 | 2021-05-26 |
| Optimal Treatment of Veterans With PTSD and Comorbid OUD Buprenorphine, Cognitive Processing Therapy (CPT), Individual Drug Counseling (IDC) - Post-Traumatic Stress Disorders, Opiate Use Disorder | Phase 2 | Terminated | VA Office of Research and Development | 38 | 2018-10-01 | 2024-08-19 |
| A Comparison of CPT Versus ART Versus WL Cognitive Processing Therapy (CPT), Accelerated Resolution Therapy (ART) - Posttraumatic Stress Disorder | Not applicable | Completed | University of Cincinnati | 187 | 2017-09-06 | 2022-12-01 |
| Cognitive Processing Therapy for Syrian Patients With PTSD Cognitive Processing Therapy (CPT) - Posttraumatic Stress Disorder (PTSD) | Not applicable | Completed | British University In Egypt | 94 | 2017-01-01 | 2021-09-02 |
| Comparative Effectiveness Research in Veterans With PTSD Cognitive Processing Therapy (CPT), Prolonged Exposure (PE) - Post-Traumatic Stress Disorder | Not applicable | Completed | VA Office of Research and Development | 916 | 2014-10-31 | 2022-02-02 |
| CPT and Smoking Cessation Cognitive Processing Therapy (CPT), Bupropion, nicotine replacement therapy (NRT) - Stress Disorders, Post-Traumatic, Smoking | Phase 2 / Phase 3 | Completed | VA Office of Research and Development | 69 | 2013-12-11 | 2018-09-11 |
| Sequence of Symptom Change During AUD or PTSD Treatment for Comorbid PTSD/AUD Cognitive Processing Therapy (CPT), Relapse Prevention (RP) - PTSD, Alcohol Abuse | Not applicable | Unknown | University of Washington | 235 | 2013-03-01 | 2018-07-18 |
| Comparison of Videoconference and Face-to-Face Delivery of Cognitive Processing Therapy for Posttraumatic Stress Disorder Cognitive Processing Therapy (CPT) - Post-Traumatic Stress Disorder | Phase 3 | Completed | University of Wisconsin, Madison | 90 | 2009-12-01 | 2015-10-02 |
Stress Disorders, Post-Traumatic (15) · Anxiety Disorders (2) · Depression (2) · Alcoholism (1) · Opioid-Related Disorders (1) · Psychological Trauma (1) · Psychological Well-Being (1) · Sleep Initiation and Maintenance Disorders (1) · Smoking (1) · Smoking Cessation (1) · Substance-Related Disorders (1) · Suicidal Ideation (1) · Suicide, Attempted (1) · Tinnitus (1) · Trauma and Stressor Related Disorders (1)
VA Office of Research and Development (3) · British University In Egypt (2) · Ohio State University (2) · The University of Texas Health Science Center at San Antonio (2) · Boston University (1) · Far Eastern Memorial Hospital (1) · University of Arkansas (1) · University of Cincinnati (1) · University of Washington (1) · University of Wisconsin, Madison (1)
United States (12) · Egypt (2) · Taiwan (1)
Kathleen M Chard, PhD (2) · Amani Elbarazi, PhD (1) · Amani S Elbarazi, Ph.D. (1) · Craig Bryan, PsyD (1) · Craig J Bryan, PsyD (1) · Debra Kaysen (1) · Elizabeth Alpert, PhD (1) · Eric A Dedert, PhD (1) · Ismene L. Petrakis, MD (1) · John C Moring, PhD (1) · Josef I Ruzek, PhD (1) · Paula P Schnurr, PhD (1) · Rebecca Sripada, PhD (1) · Stefanie LoSavio, PhD (1) · Tracey L Smith, Ph.D. (1)
PMID 26397721, PMID 30664539, PMID 35044471, PMID 36445895, PMID 38546622, PMID 38624259
1KL2TR002646-01 (1), K23MH132815 (1), R01AA020252 (1), R33DA059947 (1)