6 completed, 1 terminated. 7 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 6, Terminated 1 |
| Phase 1 | 3 | Completed 3 |
Follow Cocaine: new trials by email Literature Review of Cocaine trials Research Report on Cocaine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intranasal Cocaine and Temperature Regulation During Exercise Cocaine, Lidocaine - Hyperthermia, Cocaine Use | Phase 1 / Phase 2 | Completed | University of Texas Southwestern Medical Center | 27 | 2023-09-01 | 2025-07-14 |
| A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse RBP-8000 100 mg, Placebo, Cocaine - Opioid Dependence, Opioid Related Disorders | Phase 2 | Completed | Indivior Inc. | 40 | 2013-04-01 | 2016-09-23 |
| Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse Zonisamide, Placebo, Cocaine Hydrochloride - Cocaine Dependence | Phase 1 / Phase 2 | Completed | Johns Hopkins University | 19 | 2010-06-01 | 2017-09-05 |
| Modafinil for Smoked Cocaine Self-Administration Modafinil 0 mg, Modafinil 200 mg, Modafinil 400 mg - Cocaine Dependence | Phase 2 | Completed | New York State Psychiatric Institute | 8 | 2009-03-01 | 2018-01-09 |
| Study of Safety and Potential Efficacy of SYN117 in Cocaine Dependent Volunteers SYN117 Placebo, SYN117 80 mg, SYN117 160 mg - Cocaine Dependence | Phase 1 / Phase 2 | Completed | Biotie Therapies Inc. | 20 | 2008-06-01 | 2018-08-17 |
| Effects of Vigabatrin on Cocaine Self-Administration Vigabatrin, Cocaine - Cocaine Dependence | Phase 2 | Terminated | New York State Psychiatric Institute | 1 | 2006-04-01 | 2016-10-27 |
| Effects of Aripiprazole on Cocaine Craving and Self-Administration Aripiprazole + Cocaine, Placebo + Cocaine - Cocaine Abuse | Phase 2 | Completed | New York State Psychiatric Institute | 26 | 2005-04-01 | 2017-09-11 |
Cocaine-Related Disorders (6) · Behavior, Addictive (1) · Hyperthermia (1) · Motor Activity (1) · Opioid-Related Disorders (1) · Substance-Related Disorders (1)
New York State Psychiatric Institute (3) · Biotie Therapies Inc. (1) · Indivior Inc. (1) · Johns Hopkins University (1) · University of Texas Southwestern Medical Center (1)
United States (7)
Margaret Haney, Ph.D. (3) · Annie Umbricht, M.D. (1) · Bradley D Vince, DO (1) · F. Gerald Moeller, MD (1) · Kathryn Cunningham, PhD (1) · Stephen Bandak, MD (1)
R01DA023650 (1), R01DA027065 (1)