8 completed, 3 unknown, 2 active not recruiting, 1 terminated. 8 Phase 2, 4 Phase 3, 3 Not applicable, 3 Phase 4, 1 Phase 1.
Follow Cobalamin: new trials by email Literature Review of Cobalamin trials Research Report on Cobalamin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vitamin B12 Absorption Study Ampli-B, Vitamin B12 - Healthy Volunteers | Phase 4 | Completed | RDC Clinical Pty Ltd | 12 | 2026-07-20 | 2026-09-09 |
| Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial) Cobalamin, Dexamethasone, Docetaxel - Advanced Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma | Phase 2 / Phase 3 | Active not recruiting | SWOG Cancer Research Network | 82 | 2022-03-15 | 2026-05-18 |
| Management of Preoperative Anaemia in Surgical Oncology Ferric Carboxymaltose Injection, Folic acid, B12 - Anemia, Tumor | Phase 4 | Unknown | Azienda Ospedaliera Universitaria Integrata Verona | 500 | 2021-03-02 | 2022-08-19 |
| Vitamin B6 and B12 in the Treatment of Movement Disorders Induced by Antipsychotics Pyridoxine, Cobalamin, Placebo Oral Tablet - Schizophrenia, Drug Induced Movement Disorder, Unspecified | Phase 2 / Phase 3 | Unknown | Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara | 45 | 2019-09-03 | 2019-12-18 |
| Vitamin B12 Supplementation During Pregnancy on Cognitive Development cobalamin, placebo - Pregnancy Related, Vitamin B 12 Deficiency | Phase 2 / Phase 3 | Active not recruiting | Centre For International Health | 800 | 2017-03-27 | 2026-04-27 |
| Vitamin B12, Neurodevelopment and Growth in Nepal Vitamin B12 - Development, Vitamin Deficiency | Phase 2 / Phase 3 | Unknown | Centre For International Health | 600 | 2015-04-20 | 2023-09-18 |
| TRIM: Danish Form and Dose Study on Vitamin B12 Vitamin B12 - Healthy | Not applicable | Completed | University of Aarhus | 45 | 2014-01-01 | 2016-07-14 |
| Folic Acid and Vitamin B12 in Young Indian Children Folic Acid, Vitamin B12, Placebo - Diarrhea, Pneumonia | Phase 2 | Completed | Tor A. Strand | 1000 | 2010-01-01 | 2015-07-28 |
| Cobalamin Status in Young Children With Developmental Delay Hydroxycobalamin (Vitamin B12 Depot, Nycomed Pharma) - Vitamin B 12 Deficiency | Not applicable | Completed | Haukeland University Hospital | 100 | 2008-06-01 | 2010-08-16 |
| Oral Vitamin B12 Administration for Vitamin B12 Deficiency After Total Gastrectomy mecobalamin - Vitamin B12 Deficiency | Phase 2 | Completed | Yonsei University | 30 | 2008-04-01 | 2012-07-19 |
| Cobalamin Status in Young Children With Gastrointestinal Symptoms or Feeding Problems Hydroxycobalamin (Vitamin B12 Depot, Nycomed Pharma) - Vitamin B 12 Deficiency | Not applicable | Completed | Haukeland University Hospital | 100 | 2008-04-01 | 2010-08-16 |
| Sirolimus and Pemetrexed to Treat Non-Small Cell Lung Cancer FDG-PET, Pemetrexed, Sirolimus - Carcinoma, Non-Small-Cell Lung | Phase 1 / Phase 2 | Terminated | National Cancer Institute (NCI) | 42 | 2008-02-29 | 2019-11-26 |
| Effectiveness of Vitamin Supplementation in Treating People With Residual Symptoms of Schizophrenia Folic Acid, B12, Placebo - Schizophrenia | Phase 4 | Completed | Massachusetts General Hospital | 140 | 2007-12-01 | 2014-08-19 |
| Phase 2 Trial of Bevacizumab in Combination With Pemetrexed Bevacizumab, Pemetrexed, Vitamin B12 - Non-small Cell Lung Cancer (NSCLC), Lung Cancer | Phase 2 | Completed | Heather Wakelee | 16 | 2006-03-01 | 2017-03-06 |
Vitamin B 12 Deficiency (4) · Carcinoma, Non-Small-Cell Lung (3) · Lung Neoplasms (3) · Anemia (2) · Schizophrenia (2) · Avitaminosis (1) · Diarrhea (1) · Growth Disorders (1) · Malnutrition (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Neurologic Manifestations (1) · Pneumonia (1) · Stomach Neoplasms (1)
Centre For International Health (2) · Haukeland University Hospital (2) · Azienda Ospedaliera Universitaria Integrata Verona (1) · Heather Wakelee (1) · Massachusetts General Hospital (1) · National Cancer Institute (NCI) (1) · Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara (1) · RDC Clinical Pty Ltd (1) · SWOG Cancer Research Network (1) · Tor A. Strand (1) · University of Aarhus (1) · Yonsei University (1)
United States (4) · Nepal (2) · Norway (2) · Australia (1) · Brazil (1) · India (1) · Italy (1) · South Korea (1)
Per Magne Ueland, M.D., Ph.D. (2) · Tor A Strand, MD/PhD (2) · Alexandros Kanellopoulos (1) · Arun Rajan, M.D. (1) · Donald Goff, MD (1) · Heather A. Wakelee (1) · John M Wrangle (1) · Laxman Shestha, MD (1) · Lia LO Sanders, MD, PhD (1) · Prakash S Shrestha, MD (1) · Ram K Chandyo, MD/PhD (1) · Sunita Taneja, MBBS, PhD (1) · Tor A Strand, MD, PhD (1) · Woo Jin Hyung, Ph.D (1)
PMID 24025626, PMID 23467813, PMID 23902779, PMID 25802345, PMID 26098427, PMID 27486122, PMID 28431557, PMID 28851784, PMID 28923060, PMID 29038891, PMID 29472265, PMID 31367538, PMID 32019814, PMID 32041632, PMID 33259482, PMID 34999324, PMID 36138138, PMID 37031691, PMID 37918674, PMID 41461260, PMID 41493372, PMID 41997492
R01MH070831 (1), U10CA180888 (1)