10 completed, 2 unknown, 1 withdrawn. 13 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Completed 10, Unknown 2, Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
Follow clevidipine: new trials by email Literature Review of clevidipine trials Research Report on clevidipine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| a Study Evaluating the Safety and Efficacy of Clevidipine for Patients Who With Hypertensive Emergency and Sub-emergency QLG2071, Cleviprex® - Hypertensive Emergency | Phase 3 | Unknown | Qilu Pharmaceutical (Hainan) Co., Ltd. | 378 | 2023-07-15 | 2023-06-28 |
| A Study of Clevidipine Butyrate Injectable Emulsion in the Treatment of Hypertensive Emergency and Sub-emergency Clevidipine Butyrate Injectable Emulsion, Cleviprex® - Hypertensive Emergency | Phase 3 | Unknown | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. | 398 | 2023-05-01 | 2023-03-24 |
| Clevidipine Infusion for Blood Pressure Management After Successful Revascularization in Acute Ischemic Stroke Clevidipine - Stroke, Acute, Blood Pressure | Phase 3 | Completed | ProMedica Health System | 80 | 2021-10-30 | 2025-01-07 |
| Clevidipine vs Placebo or Standard of Care for Dyspnea and Blood Pressure Control in AHF Stage 1: Clevidipine (double-blinded), Stage 1: Placebo (double-blinded), Stage 2: Clevidipine (open-label) - Dyspnea, Hypertension | Phase 3 | Withdrawn | The Medicines Company | 2014-08-01 | 2020-10-19 | |
| An Open-label Trial of Clevidipine for Controlled Hypotension During Spinal Fusion Clevidipine - Neuromuscular Scoliosis | Phase 2 / Phase 3 | Completed | Nationwide Children's Hospital | 50 | 2012-06-01 | 2015-02-18 |
| Clevidipine in the Treatment of Blood Pressure in Patients With Acute Heart Failure (PRONTO) Clevidipine, Standard of Care IV antihypertensive - Hypertension, Heart Failure | Phase 3 | Completed | The Medicines Company | 117 | 2008-12-01 | 2014-08-29 |
| Clevidipine in the Treatment of Patients With Acute Hypertension and Intracerebral Hemorrhage (ACCELERATE) clevidipine - Hypertension, Hemorrhage | Phase 3 | Completed | The Medicines Company | 37 | 2008-06-01 | 2014-08-29 |
| Clevidipine in the Treatment of Patients With Severe Hypertension (VELOCITY) clevidipine - Hypertension | Phase 3 | Completed | The Medicines Company | 131 | 2006-09-01 | 2014-05-22 |
| Clevidipine in the Perioperative Treatment of Hypertension (ECLISPE-SNP) clevidipine, sodium nitroprusside - Hypertension | Phase 3 | Completed | The Medicines Company | 739 | 2004-06-01 | 2014-05-06 |
| Clevidipine in the Postoperative Treatment of Hypertension (ECLIPSE-NIC) clevidipine, nicardipine - Hypertension | Phase 3 | Completed | The Medicines Company | 739 | 2004-05-01 | 2014-05-06 |
| Clevidipine in the Perioperative Treatment of Hypertension (ECLIPSE-NTG) clevidipine, nitroglycerin - Hypertension | Phase 3 | Completed | The Medicines Company | 629 | 2004-04-01 | 2014-05-06 |
| Study of Clevidipine Assessing Its Preoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-1) clevidipine, placebo - Hypertension | Phase 3 | Completed | The Medicines Company | 105 | 2004-01-01 | 2014-08-22 |
| Study of Clevidipine Assessing Its Postoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-2) clevidipine, placebo - Hypertension | Phase 3 | Completed | The Medicines Company | 206 | 2003-12-01 | 2014-05-08 |
Hypertension (9) · Hypertensive Crisis (2) · Dyspnea (1) · Heart Failure (1) · Hemorrhage (1) · Stroke (1)
The Medicines Company (9) · CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. (1) · Nationwide Children's Hospital (1) · ProMedica Health System (1) · Qilu Pharmaceutical (Hainan) Co., Ltd. (1)
United States (11) · Germany (2) · France (1)
Malcolm Lloyd, MD (3) · Carmelo Graffagnino, MD (1) · Changsheng Ma (1) · Charles V Pollack, MA MD FACEP (1) · Frank Peacock, MD FACEP (1) · Joseph Tobias, MD (1) · Mouhammad Jumaa, MD (1) · W. Frank Peacock, MD (1) · William F Peacock, MD, FACEP (1) · Yuguo Chen (1)