8 completed, 1 recruiting, 1 terminated, 1 unknown. 11 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 8, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 2 | 2 | Completed 2 |
Follow Ceftaroline: new trials by email Literature Review of Ceftaroline trials Research Report on Ceftaroline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Intravenous to Oral Antibiotic Switch in Uncomplicated Staphylococcus Aureus Bacteraemia Tab. Trimethoprim-sulfamethoxazole, Tab. Clindamycin, Tab. Cephalexin, or Tab. Linezolid, IV Cloxacillin, IV Cefazolin, IV Vancomycin, or IV Ceftaroline - Staphylococcus Aureus Bacteremia | Phase 3 | Unknown | Clinical Research Centre, Malaysia | 290 | 2024-06-28 | 2024-07-05 |
| Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia Ceftriaxone + Macrolide, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam + Macrolide - Respiratory Tract Diseases, Influenza (Pandemic) | Phase 3 | Recruiting | UMC Utrecht | 20000 | 2016-04-11 | 2026-11-04 |
| Evaluation of Ceftaroline Fosamil vs Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections. Ceftaroline fosamil, Vancomycin, Aztreonam - Complicated Skin and Soft Tissue Infection | Phase 3 | Terminated | Pfizer | 4 | 2014-06-01 | 2017-09-06 |
| Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Community Acquired Bacterial Pneumonia (CABP) Ceftaroline fosamil, Ceftriaxone, amoxicillin clavulanate - Infections, Community Acquired Pneumonia | Phase 2 / Phase 3 | Completed | Forest Laboratories | 161 | 2012-09-01 | 2015-01-13 |
| Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections Ceftaroline fosamil, Vancomycin, Aztreonam - Complicated Skin and Soft Tissue Infection | Phase 3 | Completed | Pfizer | 802 | 2012-05-01 | 2017-09-06 |
| A Study to Evaluate the Efficacy and Safety of Intravenous Ceftaroline Versus Intravenous Ceftriaxone in the Treatment of Adult Hospitalised Patients With Community-Acquired Bacterial Pneumonia in Asia Ceftaroline, Ceftriaxone - Community-Acquired Bacterial Pneumonia, Lung Infection of Individual Not Recently Hospitalized | Phase 3 | Completed | Pfizer | 848 | 2011-12-01 | 2017-09-06 |
| Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Complicated Skin Infections Ceftaroline fosamil, Vancomycin +/- Aztreonam or Cefazolin +/- Aztreonam, Cephalexin or Clindamycin or Linezolid - Infections, Pediatrics | Phase 2 / Phase 3 | Completed | Forest Laboratories | 163 | 2011-12-01 | 2015-01-13 |
| Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia Ceftaroline fosamil for Injection, IV Ceftriaxone, Placebo - Bacterial Pneumonia | Phase 3 | Completed | Forest Laboratories | 606 | 2008-01-01 | 2017-03-14 |
| Comparative Study of Ceftaroline vs. Ceftriaxone in Adults With Community-Acquired Pneumonia Ceftaroline fosamil for Injection, Ceftriaxone, Placebo - Bacterial Pneumonia | Phase 3 | Completed | Forest Laboratories | 622 | 2007-07-01 | 2017-03-14 |
| Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections ceftaroline, vancomycin plus aztreonam, Placebo - Bacterial Infections | Phase 3 | Completed | Forest Laboratories | 680 | 2007-03-01 | 2017-03-14 |
| Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections IV Vancomycin plus IV Aztreonam, Ceftaroline - Bacterial Infections | Phase 3 | Completed | Forest Laboratories | 698 | 2007-02-01 | 2017-03-14 |
Bacterial Infections (4) · Cellulitis (4) · Community-Acquired Pneumonia (4) · Staphylococcal Infections (3) · Abscess (2) · Haemophilus Infections (2) · Infections (2) · Pneumonia, Bacterial (2) · Skin Diseases, Bacterial (2) · Soft Tissue Infections (2) · Staphylococcal Skin Infections (2) · Surgical Wound Infection (2) · Wound Infection (2) · Bacteremia (1) · COVID-19 (1)
Forest Laboratories (6) · Pfizer (3) · Clinical Research Centre, Malaysia (1) · UMC Utrecht (1)
Argentina (8) · Poland (8) · United States (8) · Romania (7) · Chile (6) · Germany (6) · Spain (6) · Ukraine (6) · Brazil (5) · Bulgaria (5) · Russia (5) · Hungary (4) · India (4) · Mexico (4) · South Africa (4)
David Melnick, MSD (2) · Colin McArthur, Dr (1) · David Melnick (1) · Derek Angus, Prof (1) · IM Hoepelman, MD (1) · John Marshall, Prof (1) · Lennie Derde, MD (1) · Luis Felipe Reyes, MD, MSc, PhD (1) · Marc Bonten, Prof (1) · Mark Wilcox, MD (1) · Ralph Corey, MD (1) · Steve Webb, Prof (1) · Thomas M File, MD, MS (1)
PMID 30597021, PMID 34922058, PMID 26702925, PMID 30716446, PMID 34741280, PMID 20695801, PMID 21115456, PMID 21482570, PMID 23357290, PMID 25487791, PMID 27585969, PMID 30380060, PMID 21115454, PMID 21115455, PMID 21482566, PMID 21482568, PMID 25539586, PMID 27093162, PMID 31044546, PMID 32267771, PMID 32607967, PMID 32876697, PMID 33394942, PMID 33509275, PMID 33631065, PMID 34251506, PMID 34351721, PMID 34351722, PMID 34473343, PMID 34606578, PMID 35237053, PMID 35315874, PMID 36525245, PMID 36942550, PMID 36967714, PMID 37039790, PMID 37256341, PMID 37489818, PMID 37877585, PMID 37888913, PMID 40261382, PMID 40360262, PMID 42823695
2015 (1), 2023 (1)