11 completed, 2 unknown, 1 not yet recruiting. 14 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 14 | Completed 11, Unknown 2, Not yet recruiting 1 |
| Phase 2 | 2 | Completed 1, Not yet recruiting 1 |
Follow brivaracetam: new trials by email Literature Review of brivaracetam trials Research Report on brivaracetam
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Epileptic Hippocampus in Alzheimer's Disease Brivaracetam - Alzheimer Disease, Mild Cognitive Impairment | Phase 1 / Phase 2 | Not yet recruiting | University of California, Los Angeles | 25 | 2026-01-01 | 2026-01-27 |
| Bioequivalence Study of Two Brivaracetam Oral Solutions in Healthy Adults Under Fasting and High-Fat Meal Conditions Brivaracetam Oral Solution (Test Formulation), Brivaracetam Oral Solution (Reference Formulation) - Epilepsy (treatment Refractory) | Phase 1 | Unknown | Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. | 60 | 2024-10-21 | 2025-01-08 |
| Brivaracetam Bioequivalence Assessment Briveka ® 100 mg, Briviact® 100 mg - Bioequivalence Study in Healthy Subjects | Phase 1 | Completed | Zodiac Produtos Farmaceuticos S.A. | 28 | 2024-08-09 | 2026-09-02 |
| A Study to Assess the Bioequivalence Between Brivaracetam Tablet and Dry Syrup in Healthy Japanese Male Study Participants brivaracetam (BRV) tablet, brivaracetam (BRV) dry syrup - Healthy Study Participants | Phase 1 | Completed | UCB Biopharma SRL | 64 | 2024-03-25 | 2025-06-06 |
| An Open Label, Balanced, Randomized, 3×3 Latin Square Design Comparing of Brivaracetam Sustained-release Tablets and Brivaracetam Tablets in the Oral Comparative Pharmacokinetic(PK) Study in Chinese Healthy Adult Subjects Under Fasting Conditions. Brivaracetam tablets (50mg/ tablet, BRIVIACT®, UCB), Brivaracetam sustained-release tablets 100mg, Brivaracetam sustained-release tablets 50mg - Partial Seizure | Phase 1 | Unknown | Overseas Pharmaceuticals, Ltd. | 12 | 2022-09-13 | 2023-02-01 |
| A Study to Assess the Bioequivalence Between Brivaracetam Tablet and Dry Syrup in Healthy Male Japanese Study Participants brivaracetam - Healthy Study Participants | Phase 1 | Completed | UCB Biopharma SRL | 24 | 2022-04-04 | 2024-01-05 |
| A Study to Evaluate the Pharmacokinetics and Safety of Brivaracetam in Healthy Chinese Subjects brivaracetam - Healthy Participants | Phase 1 | Completed | UCB Biopharma SRL | 12 | 2021-05-19 | 2023-03-13 |
| Brivaracetam to Reduce Neuropathic Pain in Chronic Spinal Cord Injury Brivaracetam, Placebo - Spinal Cord Injuries | Phase 1 / Phase 2 | Completed | University of Minnesota | 24 | 2021-02-01 | 2025-10-14 |
| A Study in Participants With Epilepsy, to Evaluate the Pharmacokinetics, Safety and Tolerability of Oxcarbazepine on Padsevonil Padsevonil, Oxcarbazepine, Levetiracetam - Epilepsy | Phase 1 | Completed | UCB Biopharma S.P.R.L. | 31 | 2018-09-18 | 2020-06-04 |
| A Brain Imaging Study With Positron Emission Tomography and the Radiotracer [11C]UCB-J to Estimate How Fast Brivaracetam and Levetiracetam Enter the Brain in Healthy Volunteers [11C]UCB-J, Brivaracetam, Levetiracetam - Healthy Volunteers | Phase 1 | Completed | UCB Pharma | 13 | 2015-11-01 | 2017-10-30 |
| Comparison of Brivaracetam Oral Tablet (10 mg, 50 mg, 75 mg and 100 mg) and Brivaracetam Injection (100 mg) in Healthy Volunteers Brivaracetam 10 mg oral tablet, Brivaracetam 50 mg oral tablet, Brivaracetam 75 mg oral tablet - Healthy Volunteers | Phase 1 | Completed | UCB Pharma SA | 25 | 2013-01-01 | 2013-04-15 |
| A Study to Investigate the Drug-Drug Interactions of Brivaracetam and Ethanol in Healthy Male Subjects Brivaracetam, Ethanol, Brivaracetam Placebo - Healthy Volunteers | Phase 1 | Completed | UCB Pharma SA | 18 | 2012-09-01 | 2018-10-11 |
| Clinical Study in Healthy Volunteers to Investigate the Neurocognitive Effects of a New Antiepileptic Drug: Brivaracetam Brivaracetam, levetiracetam, lorazepam - Epilepsy | Phase 1 | Completed | UCB Pharma | 20 | 2008-07-01 | 2012-05-28 |
| An Open-Label Interaction Study to Look at the Effects of Brivaracetam on Phenytoin When Taken Together in 15 Adult Patients With Epilepsy. Brivaracetam (ucb34714) - Epilepsy | Phase 1 | Completed | UCB Pharma | 15 | 2005-04-01 | 2008-03-10 |
Epilepsy (6) · Alzheimer Disease (1) · Cognitive Dysfunction (1) · Seizures (1) · Spinal Cord Injuries (1)
UCB Biopharma SRL (3) · UCB Pharma (3) · UCB Pharma SA (2) · Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (1) · Overseas Pharmaceuticals, Ltd. (1) · UCB Biopharma S.P.R.L. (1) · University of California, Los Angeles (1) · University of Minnesota (1) · Zodiac Produtos Farmaceuticos S.A. (1)
United States (5) · China (3) · Netherlands (3) · Japan (2) · Brazil (1) · Bulgaria (1)
Keith A Vossel, MD, MSc (1) · Leslie Morse, DO (1) · Philipp von Rosenstiel, M.D. (1) · Scott Falci, MD (1)
PMID 20887370, PMID 30924924, PMID 34570177, PMID 38932723, PMID 41998831
2018 (1)