5 completed, 2 terminated, 1 not yet recruiting, 1 recruiting. 10 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 5, Terminated 2, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 1 | 2 | Completed 2 |
Follow Brain MRI: new trials by email Literature Review of Brain MRI trials Research Report on Brain MRI
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Rituximab for Remission Maintenance in Patients With Primary Angiitis of the Central Nervous System: an Open-label, Randomized, Controlled Trial Comparing Systematic Rituximab Infusions and Azathioprine RUXIENCE®., Brain MRI, Azathioprine 50 MG - Primary Angiitis of the Central Nervous System (PACNS) in Remission | Phase 2 | Not yet recruiting | Centre Hospitalier St Anne | 74 | 2027-01-01 | 2026-10-29 |
| Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1 [C-11]-CS1P1, Brain MRI - Central Nervous System Cancer, Brain Metastases | Phase 2 | Recruiting | Washington University School of Medicine | 104 | 2026-04-16 | 2026-04-21 |
| Sacituzumab Govitecan for Relapsed Ovarian, Endometrial, and Cervical Carcinomas Sacituzumab Govitecan, EKG, Brain MRI - Recurrent Platinum Resistant Epithelial Ovarian Carcinoma, Recurrent Epithelial Endometrial Carcinoma | Phase 2 | Terminated | National Cancer Institute (NCI) | 2 | 2025-06-09 | 2026-01-21 |
| Phase 2 Study of Bintrafusp Alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON). Bintrafusp alfa/M7824, Ibuprofen, PET scan - Olfactory Neuroblastoma, Esthesioneuroblastoma | Phase 2 | Completed | National Cancer Institute (NCI) | 11 | 2022-06-21 | 2025-08-08 |
| HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers PRGN-2009, M7824, EKG - HPV Positive Cancer, Vulvar, Vaginal, Penile, Rectal Cancer | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 39 | 2020-08-11 | 2026-08-18 |
| Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene. Methionine, Vitamin B12, B9, B6, C supplementation, Methionine/homocysteine Dosage - Pulmonary Alveolar Proteinosis, Mutation Ala393Thr of the MARS Gene | Phase 1 / Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 3 | 2019-09-16 | 2025-11-20 |
| TTFields and Pulsed Bevacizumab for Recurrent Glioblastoma Bevacizumab, Optune, Brain MRI - Glioblastoma Multiforme, Glioblastoma | Phase 2 | Terminated | University of Florida | 10 | 2016-12-19 | 2022-06-23 |
| Oral Steroids for Regorafenib-induced Fatigue/Malaise in Unresectable mCRC (KSCC1402/HGCSG1402) General condition, Blood pressure, Patient Reported Outcome - Rectal Cancer | Phase 2 | Unknown | Clinical Research Support Center Kyush | 74 | 2014-10-01 | 2014-11-13 |
| Monocentric Pilot Study, for a Randomized, Crossover, Blinded Trial: Comparison of the Therapeutic Efficacy of Low Frequency Repeated Transcranial Magnetic Stimulation on Cortical Area 9 Compared to Brodmann Area 46 in the Treatment of Depressive Disorders. rTMS BA9/BA46, rTMS BA46/BA9, brain MRI - Patients With Resistant Depressive Disorders | Phase 2 | Completed | Centre Hospitalier Universitaire Dijon | 17 | 2010-02-01 | 2018-09-04 |
| Treatment and Natural History Study of Lymphomatoid Granulomatosis Interferon, Rituxan and EPOCH, Tumor biopsy - Lymphomatoid Granulomatosis, Granulomatosis, Lymphomatoid | Phase 2 | Completed | National Cancer Institute (NCI) | 94 | 1995-05-05 | 2025-06-19 |
Glioblastoma (2) · Glioma (2) · Rectal Neoplasms (2) · Anus Neoplasms (1) · Astrocytoma (1) · Brain Neoplasms (1) · Central Nervous System Neoplasms (1) · Epstein-Barr Virus Infections (1) · Esthesioneuroblastoma, Olfactory (1) · Fatigue (1) · Lymphoma (1) · Lymphoma, Non-Hodgkin (1) · Lymphomatoid Granulomatosis (1) · Lymphoproliferative Disorders (1) · Nose Neoplasms (1)
National Cancer Institute (NCI) (4) · Assistance Publique - Hôpitaux de Paris (1) · Centre Hospitalier St Anne (1) · Centre Hospitalier Universitaire Dijon (1) · Clinical Research Support Center Kyush (1) · University of Florida (1) · Washington University School of Medicine (1)
United States (6) · France (2) · Japan (1)
Charalampos Floudas, M.D. (2) · Christopher J Melani, M.D. (1) · David D Tran, MD, PhD (1) · Kevin C Conlon, M.D. (1) · Tammie L.S. Benzinger, M.D., Ph.D. (1) · Yasunori Emi, MD, PhD (1)
PMID 34503986, PMID 37011643, PMID 39500789, PMID 40116923, PMID 42307670
2018 (1)