16 completed, 1 active not recruiting, 1 withdrawn. 18 Phase 3, 1 Phase 2.
By phase and status
Follow Boostrix: new trials by email Literature Review of Boostrix trials Research Report on Boostrix
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All 18 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
A Study on the Immune Response and Safety of a Combined Vaccine Against Diphtheria, Tetanus and Acellular Pertussis (dTpa) in Japanese Healthy Pregnant Women dTpa - Diphtheria-Tetanus-acellular Pertussis Vaccines | Phase 3 | Active not recruiting | 102 | 2026-06-29 | 2026-09-08 |
GBS-NN/NN2 (50 µg of Each Fusion Protein [GBS-NN and GBS-NN2] in Combination With 500 µg Aluminum as Alhydrogel®) Given With and Without the Tdap Vaccine in Healthy Non-pregnant Women 18 to 49 Years of Age GBS-NN/NN2 vaccine, Tdap vaccine, Placebo - Streptococcus Agalactiae Infection | Phase 2 / Phase 3 | Withdrawn | | 2024-12-17 | 2026-10-13 |
A Study to Evaluate the Safety and Immune Response to an Unadjuvanted RSV Maternal Vaccine in Healthy Non-pregnant Females From 9 to 49 Years of Age RSV MAT vaccine, dTpa vaccine - Respiratory Syncytial Virus Infections | Phase 3 | Completed | 9 | 2022-02-02 | 2023-04-07 |
Evaluation of Immunogenicity, Safety and Reactogenicity of GSK Biologicals' Boostrix Vaccine Administered as a Booster Dose in Healthy Russian Subjects Boostrix - Diphtheria-Tetanus-acellular Pertussis Vaccines | Phase 3 | Completed | 448 | 2018-01-26 | 2020-10-27 |
Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of an MF59-Adjuvanted Quadrivalent Influenza Vaccine Compared to Non-influenza Vaccine Comparator in Adults ≥ 65 Years of Age MF59-adjuvanted Quadrivalent Subunit Inactivated Egg-derived Influenza Vaccine (aQIV), Non-Influenza Comparator (Boostrix) - Influenza | Phase 3 | Completed | 6790 | 2016-09-30 | 2020-06-17 |
Safety of a Booster Dose of GlaxoSmithKline (GSK) Biologicals' Boostrix™ Vaccine in Healthy Vietnamese Children Boostrix™ - Diphtheria, Tetanus | Phase 3 | Completed | 302 | 2014-02-22 | 2018-08-02 |
Study to Assess the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine (GSK1437173A) When Co-administered With GSK Biologicals' Diphtheria, Tetanus and Pertussis Vaccine (Boostrix®) in Adults Aged 50 Years and Older Herpes Zoster vaccine GSK 1437173A, Boostrix - Herpes Zoster | Phase 3 | Completed | 935 | 2014-02-07 | 2018-04-24 |
Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Boostrix™ Vaccine in Previously Boosted Young Adults Boostrix - Tetanus, Acellular Pertussis | Phase 3 | Completed | 165 | 2013-01-31 | 2018-06-06 |
Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Meningococcal Vaccine With or Without Co-administration of Cervarix and Boostrix in Female Adolescents and Young Adults Meningococcal vaccine GSK134612, Cervarix®, Boostrix® - Infections, Meningococcal | Phase 3 | Completed | 1300 | 2013-01-11 | 2018-07-03 |
Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Meningococcal Conjugate Vaccine (GSK134612) When Co-administered With Boostrix® in Subjects Between 11 and 25 Years of Age Meningococcal vaccine GSK134612, Boostrix® - Infections, Meningococcal | Phase 3 | Completed | 692 | 2013-01-10 | 2017-09-06 |
Evaluation of GlaxoSmithKline Biologicals' Boostrix® Vaccine in Comparison With Decavac™ Vaccine. Boostrix®, Decavac™ - Tetanus, Acellular Pertussis | Phase 3 | Completed | 1332 | 2009-02-17 | 2020-01-03 |
Persistence Study of GSK Biologicals' Tdap Vaccine 1, 3, 5 and 9 Years Following Administration as an Initial Single Dose in Healthy Young Adults and to Evaluate the Immunogenicity and Safety of Boostrix as a Second Dose of Tdap, When Administered at Year 9 Taking of blood samples, Boostrix, Adacel - Acellular Pertussis, Tetanus | Phase 3 | Completed | 1954 | 2007-06-01 | 2020-05-01 |
Study to Assess Safety & Immunogenicity of GSK Biologicals' Boostrix (dTpa) Vaccine vs. Chinese DT Vaccine Boostrix, Chinese DT vaccine - Diphtheria, Acellular Pertussis | Phase 3 | Completed | 660 | 2007-03-01 | 2016-10-28 |
Study to Assess the Safety & Reactogenicity of GSK Biologicals' dTpa Vaccine (Boostrix) When Given at 6-8 Years of Age. Boostrix - Tetanus, Diphtheria | Phase 3 | Completed | 30 | 2007-01-01 | 2016-10-27 |
Immunogenicity, Safety of GSKs Tdap Vaccine Boostrix When Coadministered With GSKs Influenza Vaccine Fluarix in Adults Fluarix®, Boostrix® - Acellular Pertussis, Diphtheria | Phase 3 | Completed | 1726 | 2006-10-23 | 2019-06-10 |
Safety and Immunogenicity of GSK's Tdap Vaccine (Boostrix) in Adults Aged 19 to 64 Years Boostrix™, ADACEL® - Acellular Pertussis, Diphtheria | Phase 3 | Completed | 2337 | 2006-07-13 | 2018-08-07 |
PneuMum: Pneumococcal Vaccination of Australian Indigenous Mothers 23vPPV, dTpa (Pneumovax, Boostrix) - Middle Ear Effusion, Tympanic Membrane Perforation | Phase 3 | Completed | 227 | 2006-06-01 | 2014-07-10 |
Comparison of GSK Biologicals' Reduced Antigen Diphtheria and Tetanus Toxoids and Acellular Pertussis- Inactivated Poliovirus Vaccine, to BoostrixTM and Inactivated Poliovirus Vaccine Administered Separately and With Revaxis® GSK Biologicals' reduced antigen diphtheria and tetanus toxoids and acellular pertussis- inactivated poliovirus vaccine, Boostrix™, GSK Biologicals' IPV vaccine - Tetanus, Diphtheria | Phase 3 | Completed | 806 | 2002-01-01 | 2016-09-07 |
Conditions studied
Tetanus (14) · Diphtheria (13) · Whooping Cough (4) · Influenza, Human (2) · Meningococcal Infections (2) · Herpes Zoster (1) · Meningitis, Meningococcal (1) · Otitis Media (1) · Otitis Media with Effusion (1) · Pneumococcal Infections (1) · Respiratory Syncytial Virus Infections (1) · Streptococcal Infections (1) · Tympanic Membrane Perforation (1)
Sponsors
GlaxoSmithKline (15) · Menzies School of Health Research (1) · Minervax ApS (1) · Seqirus (1)
Countries
United States (7) · China (2) · Dominican Republic (2) · Estonia (2) · Thailand (2) · Australia (1) · Bulgaria (1) · Colombia (1) · Czechia (1) · Germany (1) · Japan (1) · Latvia (1) · Lithuania (1) · Malaysia (1) · Philippines (1)
Top investigators
Amanda J Leach, PhD (1) · Edward K Mulholland, DM (1) · Jonathan R Carapetis, PhD (1) · Mimi LK Tang, PhD (1) · Paul J Torzillo, MBBS (1) · Peter S Morris, PhD (1) · Ross M Andrews, PhD (1)
Results publications
PMID 15882526, PMID 21945698, PMID 25882172, PMID 26529076, PMID 29789243, PMID 29960800, PMID 30603376, PMID 31443993, PMID 33577767, PMID 36211411, PMID 41276263
NIH funding
2015 (2), 2023 (1)