9 completed, 4 unknown, 2 terminated, 1 withdrawn. 14 Phase 1, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 14 | Completed 9, Unknown 3, Terminated 2 |
| Phase 2 | 6 | Completed 2, Unknown 2, Terminated 1, Withdrawn 1 |
Follow Bevacizumab-IRDye800CW: new trials by email Literature Review of Bevacizumab-IRDye800CW trials Research Report on Bevacizumab-IRDye800CW
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Targeted Fluorescence Imaging in AMD Bevacizumab-IRDye800CW - Age-Related Macular Degeneration, NAMD | Phase 1 | Completed | University Medical Center Groningen | 12 | 2022-10-28 | 2024-12-06 |
| Thyroid Cancer and Central Lymph Node Metastases Detection Using Bevacizumab-IRDye800CW Bevacizumab-IRDye800CW - Thyroid Carcinoma, Surgery | Phase 1 | Completed | University Medical Center Groningen | 20 | 2021-11-29 | 2024-08-22 |
| Improvement of the Operative Outcome in Patients With Primary VEGF + Unifocal Breast Cancer or DCIS Through the Intraoperative Visualization of the Tumor Using Molecular Imaging and Bevacizumab-IRDye-800CW Bevacizumab-IRDye800CW - Breast Cancer | Phase 2 | Withdrawn | Technical University of Munich | 2021-06-01 | 2022-05-04 | |
| Detection of PitNET Tissue During TSS Using Bevacizumab-800CW Bevacizumab-IRDye800CW, Molecular Fluorescence Endoscopy platform - Pituitary Tumor, Pituitary Adenoma | Phase 1 | Completed | University Medical Center Groningen | 20 | 2020-10-28 | 2023-04-14 |
| Detection of Early Esophageal Cancer by NIR-FME. Bevacizumab-IRDye800CW, Fluorescence endoscopy - Barrett Esophagus | Phase 2 | Unknown | University Medical Center Groningen | 60 | 2019-07-29 | 2020-11-04 |
| Image Guided Surgery in Sinonasal Inverted Papilloma Bevacizumab-800CW - Inverted Papilloma, Molecular Fluorescence Imaging | Phase 1 | Unknown | University Medical Center Groningen | 6 | 2019-05-06 | 2021-05-03 |
| Fluorescence Image Guided Surgery in Cholangiocarcinoma Bevacizumab-IRDye800CW, near infrared (NIR) fluorescence imaging - Hilar Cholangiocarcinoma | Phase 1 / Phase 2 | Unknown | University Medical Center Groningen | 12 | 2019-04-01 | 2021-04-28 |
| Fluorescence Endoscopy of Esophageal Carcinoma Bevacizumab-IRDye800CW, Molecular Fluorescence Endoscopy platform - Esophageal Cancer | Phase 1 | Terminated | University Medical Center Groningen | 25 | 2018-10-29 | 2024-04-16 |
| FLuoresence Image Guided Surgery With A VEGF-targeted Tracer in Soft-tissue Sarcomas in Humans Approach With Bevacizumab-IRDye 800CW Bevacizumab-IRDye800CW - Soft Tissue Sarcoma | Phase 1 / Phase 2 | Completed | University Medical Center Groningen | 16 | 2018-05-01 | 2020-01-28 |
| Feasibility Study of Using Molecular Fluorescence Guided Surgery in Endometriosis Bevacizumab-800CW - Endometriosis | Phase 1 | Unknown | University Medical Center Groningen | 10 | 2017-05-01 | 2017-06-27 |
| Near-infrared Image Guided Surgery in Pancreatic Adenocarcinoma Bevacizumab-800CW - Pancreatic Cancer, Pancreatic Adenocarcinoma | Phase 1 / Phase 2 | Terminated | University Medical Center Groningen | 10 | 2016-12-01 | 2020-01-28 |
| Fluorescence Guided Surgery in Breast Cancer Bevacizumab-800CW - Breast Cancer | Phase 1 / Phase 2 | Completed | University Medical Center Groningen | 26 | 2015-10-01 | 2017-02-13 |
| VEGF-targeted Fluorescence Near-Infrared (NIR) Endoscopy in (Pre)Malignant Esophageal Lesions Bevacizumab-IRDye800CW, Near infrared fluorescence endoscopy platform - Esophageal Cancer, Dysplasia | Phase 1 | Completed | University Medical Center Groningen | 14 | 2014-04-01 | 2024-04-16 |
| Molecular Fluorescence Endoscopy in Patients With Familial Adenomatous Polyposis, Using Bevacizumab-IRDye800CW Bevacizumab-IRDye800CW, Near infrared fluorescence endoscopy platform - Adenomatous Polyposis Coli | Phase 1 | Completed | University Medical Center Groningen | 17 | 2014-03-01 | 2023-10-27 |
| Visualization of Rectal Cancer During Endoscopy, Using a Fluorescent Tracer Bevacizumab-IRDye800CW, NIR fluorescence endoscopy - Rectal Cancer | Phase 1 | Completed | University Medical Center Groningen | 30 | 2013-10-01 | 2024-04-16 |
| VEGF-targeted Fluorescent Tracer Imaging in Breast Cancer bevacizumab-IRDye800CW - Breast Cancer | Phase 1 | Completed | University Medical Center Groningen | 20 | 2011-10-01 | 2017-10-27 |
Breast Neoplasms (3) · Esophageal Neoplasms (2) · Adenomatous Polyposis Coli (1) · Barrett Esophagus (1) · Endometriosis (1) · Klatskin Tumor (1) · Macular Degeneration (1) · Pancreatic Neoplasms (1) · Papilloma, Inverted (1) · Pituitary Neoplasms (1) · Rectal Neoplasms (1) · Sarcoma (1) · Thyroid Neoplasms (1)
University Medical Center Groningen (15) · Technical University of Munich (1)
Netherlands (15)
G. M. van Dam, MD, PhD (2) · W. B. Nagengast, MD, PhD, PharmD (2) · Wouter B Nagengast, PharmD MD PhD (2) · Frans TM Peters, MD PhD (1) · G.M van Dam, prof. dr. (1) · Geke AP Hospers, Prof. dr. (1) · Go M. van Dam, MD, PhD (1) · Gooitzen van Dam, MD (1) · Gooitzen van Dam, MD, PhD (1) · Gooitzen van Dam, prof dr (1) · Jan H Kleibeuker, MD, senior full professor (1) · Jan Jakob Koornstra, MD PhD (1) · M. T. de Boer, MD, PhD (1) · Vasilis Ntziachristos, Prof. Dr. (1)
PMID 29247063, PMID 31533965, PMID 31628218, PMID 34620658, PMID 34738141, PMID 37938137, PMID 39390132, PMID 41344859