16 completed, 1 active not recruiting, 1 unknown. 14 Not applicable, 2 Phase 1, 2 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Completed 13, Active not recruiting 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 1 | Unknown 1 |
Follow Aspartame: new trials by email Literature Review of Aspartame trials Research Report on Aspartame
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effects of Dietary Erythritol on Platelet Reactivity and Vascular Inflammation Erythritol, Aspartame - Platelet Aggregation, Spontaneous, Vascular Thrombosis | Not applicable | Active not recruiting | University of California, Davis | 14 | 2023-07-20 | 2026-09-14 |
| Reproducibility and Utility of OGTT in Acromegaly Performed 3 diagnostic tests (2 OGTT tests with 75 g of Glucose and 1 placebo test with 375 mg of Aspartam, Performed 2 diagnostic tests (2 OGTT tests with 75g of Glucose) - Acromegaly | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 109 | 2020-08-24 | 2025-11-24 |
| Effectiveness of Hydroxychloroquine in Covid-19 Patients Hydroxychloroquine 200 Mg Oral Tablet, Azithromycin 500Mg Oral Tablet, Glucose tablets - COVID19 | Phase 3 | Unknown | Prof. Dr. Umar Farooq | 75 | 2020-03-28 | 2020-04-02 |
| Food Intake and the Adolescent Brain Energy Stimulus - Feeding Behavior, Brain | Completed | University of Colorado, Denver | 63 | 2019-12-30 | 2025-06-08 | |
| Transport of Artificial Sweeteners During Pregnancy Acesulfame K, cyclamate, saccharine, aspartame - Pregnancy Related, Diabetes | Not applicable | Completed | University of Aarhus | 35 | 2019-06-01 | 2021-02-24 |
| Assessment of Satiety Following Oral Administration of an Erythritol Sweetened Beverage Erythritol, Aspartame - Satiety in Healthy Volunteers | Not applicable | Completed | University of Florida | 12 | 2017-09-18 | 2019-08-28 |
| Microbiome and Non-caloric Sweeteners in Humans Glucose, Aspartame, Sucralose - Glucose Intolerance, Glucose, Low Blood | Not applicable | Completed | Weizmann Institute of Science | 120 | 2017-02-19 | 2021-08-04 |
| The Effects of Aspartame on Appetite, Body Composition and Oral Glucose Tolerance aspartame, water - Oral Glucose Tolerance | Not applicable | Completed | Purdue University | 93 | 2016-08-17 | 2018-01-18 |
| Enteroendocrine Hormonal Response After the Ingestion of Cola Beverages With Sucrose and Non-nutritive Sweeteners Cola beverage with aspartame and acesulfame K, Cola beverage with sucrose and stevia - Obesity, Diabetes Mellitus, Type 2 | Not applicable | Completed | Hospital Infantil de Mexico Federico Gomez | 20 | 2016-02-08 | 2022-12-16 |
| Adverse Metabolic Effects of Dietary Sugar high fructose corn syrup, aspartame, Energy-balanced diet - Chronic Disease of Cardiovascular System, Type 2 Diabetes | Not applicable | Completed | University of California, Davis | 36 | 2016-02-01 | 2021-09-16 |
| NUTRALYS® Pea Protein Oral Supplementation Effects on Muscle Mass oral powder in sachet - Healthy | Not applicable | Completed | Nicolas Babault | 150 | 2012-01-01 | 2014-05-01 |
| Green Tea Lozenges for the Management of Dry Mouth MighTeaFlow, Xylitol - Xerostomia, Sjogren Syndrome | Phase 1 / Phase 2 | Completed | Augusta University | 60 | 2011-03-01 | 2015-03-18 |
| Metabolic Effects of Non-Nutritive Sweeteners Sucralose, Aspartame, Acesulfame-Potassium - Healthy Volunteers | Phase 1 / Phase 2 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 118 | 2010-11-04 | 2021-01-22 |
| Effects of Sucrose Added Blind to the Diet Over Eight Weeks on Body Mass and Weight in Men Sucrose - Overweight | Not applicable | Completed | University of Hull | 80 | 2010-08-01 | 2021-03-18 |
| The Metabolic Effects of Consuming Sugar-Sweetened Beverages for Two Weeks Glucose, Fructose, High-Fructose Corn Syrup - Metabolic Syndrome, Insulin Resistance | Not applicable | Completed | University of California, Davis | 214 | 2008-10-01 | 2017-05-30 |
| MEDEX Hidden Valley 2008 Carbohydrate energy drink, Aspartame - Hypoxia | Not applicable | Completed | Medical Expeditions Ltd | 44 | 2008-06-01 | 2017-03-31 |
| Effects of the Sugar Sucrose on Bodyweight and Energy Intake Over 28 Days in Obese Women Sucrose, Aspartame - Obesity | Not applicable | Completed | University of Hull | 41 | 2006-09-01 | 2016-01-28 |
| Effects of Stevia on Satiety and Eating Attitudes in Healthy, Overweight and Obese Adults Aspartame, Sucrose, Stevia - Obesity, Type 2 Diabetes | Not applicable | Completed | Pennington Biomedical Research Center | 30 | 2006-01-01 | 2016-02-12 |
Obesity (4) · Diabetes Mellitus, Type 2 (3) · Metabolic Syndrome (2) · Acromegaly (1) · Altitude Sickness (1) · COVID-19 (1) · Diabetes Mellitus (1) · Dyslipidemias (1) · Feeding Behavior (1) · Glucose Intolerance (1) · Hypoxia (1) · Insulin Resistance (1) · Multiple Endocrine Neoplasia Type 1 (1) · Overweight (1) · Pediatric Obesity (1)
University of California, Davis (3) · University of Hull (2) · Assistance Publique - Hôpitaux de Paris (1) · Augusta University (1) · Hospital Infantil de Mexico Federico Gomez (1) · Medical Expeditions Ltd (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Nicolas Babault (1) · Pennington Biomedical Research Center (1) · Prof. Dr. Umar Farooq (1) · Purdue University (1) · University of Aarhus (1) · University of Colorado, Denver (1) · University of Florida (1) · Weizmann Institute of Science (1)
United States (9) · France (2) · Denmark (1) · Israel (1) · Pakistan (1) · United Kingdom (1)
America L Miranda-Lora, PhD (1) · Cesar Galicia-Ayala, Master (1) · Eran Elinav (1) · Francois A Allaert, MD (1) · Jamie H Macdonald, PhD (1) · Jean-Marc Schwarz, Ph.D. (1) · Kimber L Stanhope, Ph.D, R.D. (1) · Kimber L Stanhope, Ph.D. (1) · Mark L Brantly, MD (1) · Per Ovesen, DMSc (1) · Peter J Havel, D.V.M (1) · Peter J Havel, DVM, Ph.D (1)
PMID 19793859, PMID 24164779, PMID 25240992, PMID 25628520, PMID 25879513, PMID 25904601, PMID 27777606, PMID 29659969, PMID 32916151, PMID 34265055, PMID 34986271
K01DK120562 (1), R01HL091333 (1), R01HL107256 (1), R01HL121324 (1)