7 completed. 7 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 7 |
| Phase 2 | 2 | Completed 2 |
Follow Artificial tears: new trials by email Literature Review of Artificial tears trials Research Report on Artificial tears
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate 0.003% AR-15512 Safety and Drop Attributes 0.003% AR-15512 ophthalmic solution, Artificial tears - Dry Eye Disease | Phase 3 | Completed | Alcon Research | 55 | 2025-01-15 | 2026-03-17 |
| A Study to Investigate the Effect of 0.003% AR-15512 on Subjects With Dry Eye Disease 0.003% AR-15512 ophthalmic solution, Artificial Tears - Dry Eye Disease | Phase 3 | Completed | Alcon Research | 80 | 2024-10-08 | 2026-03-27 |
| Aqueous Humor Dynamics of NCX 470 Ophthalmic Solution NCX 470, Placebo - Open Angle Glaucoma | Phase 2 / Phase 3 | Completed | Nicox Ophthalmics, Inc. | 18 | 2023-12-12 | 2025-09-08 |
| FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial Fluorometholone 0.1% Oph Susp, Artificial Tears - Trachomatous Trichiasis (TT), Eye Diseases | Phase 3 | Completed | Massachusetts Eye and Ear Infirmary | 2410 | 2021-08-19 | 2026-03-24 |
| Dorzolamide-timolol in Combination With Anti-vascular Endothelial Growth Factor Injections for Wet Age-related Macular Degeneration Dorzolamide-timolol, Artificial tears - Neovascular Age-related Macular Degeneration, Wet Macular Degeneration | Phase 2 / Phase 3 | Completed | Wills Eye | 52 | 2017-02-08 | 2020-06-19 |
| Efficacy and Safety of Fluorometholone (FML) in Dry Eye Disease (Keratoconjunctivitis Sicca) FML 0.1% eyedrops, Liquifilm artificial tears eyedrops - Dry Eye | Phase 3 | Completed | Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA | 41 | 2014-02-01 | 2015-01-08 |
| A Trial of Topical Dexamethasone Versus Artificial Tears for Treatment of Viral Conjunctivitis dexamethasone 0.1%/povidone-iodine 0.4%, Artificial Tears - Viral Conjunctivitis | Phase 3 | Completed | University of Campinas, Brazil | 100 | 2011-12-01 | 2014-12-04 |
Dry Eye Syndromes (3) · Conjunctivitis (1) · Conjunctivitis, Viral (1) · Eye Diseases (1) · Eyelid Diseases (1) · Glaucoma (1) · Glaucoma, Open-Angle (1) · Keratoconjunctivitis Sicca (1) · Macular Degeneration (1) · Trichiasis (1) · Wet Macular Degeneration (1)
Alcon Research (2) · Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA (1) · Massachusetts Eye and Ear Infirmary (1) · Nicox Ophthalmics, Inc. (1) · University of Campinas, Brazil (1) · Wills Eye (1)
United States (4) · Brazil (1) · Ethiopia (1) · Spain (1)
Jason Hsu, MD (1) · John H Kempen, MD MPH MHS PhD (1) · Margarita Calonge-Cano, MD, PhD (1) · Rodrigo Pessoa C Lira (1)
PMID 32239190, PMID 39006430, PMID 39656933, PMID 40737343, PMID 41539314