9 completed, 2 terminated, 1 not yet recruiting, 1 unknown. 13 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Completed 9, Terminated 2, Not yet recruiting 1, Unknown 1 |
Follow Artificial tears: new trials by email Literature Review of Artificial tears trials Research Report on Artificial tears
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Behavioral Intervention (Baduanjin Alone or Laughter Exercise Plus Artificial Tears) Versus Artificial Tear on Dry Eye Disease: a Randomised Controlled Trial Baduanjin, Laughter exercise, Artificial tears - Dry Eye Disease (DED) | Not applicable | Not yet recruiting | Zhongshan Ophthalmic Center, Sun Yat-sen University | 540 | 2027-01-01 | 2026-04-13 |
| Efficacy of Pilocarpine As a Secretagogue Versus Artificial Tears for the Treatment of Dry Eye Pilocarpine, artificial tears - Dry Eye Disease (DED) | Not applicable | Completed | Al-Azhar University | 40 | 2024-10-01 | 2024-12-30 |
| Medical vs Acupuncture for Dry Eye Artificial tears, Traditional Chinese Medicine Acupuncture - Dry Eye, Acupuncture | Not applicable | Completed | Nadide Koca | 90 | 2024-01-15 | 2025-09-22 |
| Diquafosol Ophthalmic Solution for Dry Eye Symptoms 3% Diquafosol tetrasodium, 0.1% hyaluronate - Diabetic Eye Problems | Not applicable | Unknown | He Eye Hospital | 101 | 2023-03-03 | 2023-01-12 |
| Diquafosol vs Hyaluronic Acid for Diabetic Dry Eye 3% Diquafosol tetrasodium, 0.1% hyaluronate - Diabetic Eye Problems | Not applicable | Completed | He Eye Hospital | 99 | 2022-12-01 | 2025-07-25 |
| Study on Curative Effect and Mechanism of Acupuncture on Neuropathic Pain in Dry Eye Disease Sodium hyaluronate eye drops, acupuncture - Dry Eye | Not applicable | Completed | Peking University Third Hospital | 20 | 2020-09-22 | 2022-11-23 |
| Optimization of Sampling and Processing of Samples for Molecular Microbial Research on Ocular Surface Samples Conjunctival swab, Oxybuprocaine Hydrochloride 0.4% Eye Drops, artificial tears - Microbiota, Ocular Surface | Not applicable | Completed | Universitaire Ziekenhuizen KU Leuven | 24 | 2019-08-19 | 2022-07-22 |
| Effect of Topical and Oral Diclofenac on Pain Related to Intravitreal Injections Diclofenac Eye Drops, Pacebo pill, Oral Diclofenac - Pain | Not applicable | Completed | University Hospital of Patras | 76 | 2016-07-01 | 2017-01-10 |
| Timolol Eye Drops in the Treatment of Acute Migraine Headache Timolol eye drops, Artificial tears - Migraine | Not applicable | Terminated | University of Missouri, Kansas City | 10 | 2016-01-01 | 2019-05-15 |
| Reducing Adenoviral Patient Infected Days Betadine 5%, Artificial Tears - Conjunctivitis, Adenoviral Conjunctivitis | Not applicable | Completed | Washington University School of Medicine | 28 | 2015-03-23 | 2021-01-06 |
| Ocular Surface Disorders in Patients in Intensive Care Units, a Comparative Study of Three Preventive Approaches Aqueous Gel, Eyelid Occlusion Dressing, Artificial Tears - Corneal Diseases | Not applicable | Completed | Fondation Ophtalmologique Adolphe de Rothschild | 49 | 2014-12-01 | 2017-02-13 |
| The Effects of Cyclosporin A in a Low Humidity Environment, on the Ocular Surface Cyclosporin 0.05% emulsion, Endura, Refresh artificial tears - Dry Eye | Not applicable | Terminated | Baylor College of Medicine | 4 | 2014-03-01 | 2020-02-20 |
| Systane Ultra Versus Maxidex Versus Saline Systane Ultra, Saline solution, Maxidex - Dry Eye Disease | Not applicable | Completed | Icahn School of Medicine at Mount Sinai | 36 | 2012-05-01 | 2013-01-25 |
Dry Eye Syndromes (8) · Pain (2) · Conjunctivitis (1) · Corneal Diseases (1) · Corneal Injuries (1) · Headache (1) · Keratoconjunctivitis Sicca (1) · Migraine Disorders (1)
He Eye Hospital (2) · Al-Azhar University (1) · Baylor College of Medicine (1) · Fondation Ophtalmologique Adolphe de Rothschild (1) · Icahn School of Medicine at Mount Sinai (1) · Nadide Koca (1) · Peking University Third Hospital (1) · Universitaire Ziekenhuizen KU Leuven (1) · University Hospital of Patras (1) · University of Missouri, Kansas City (1) · Washington University School of Medicine (1) · Zhongshan Ophthalmic Center, Sun Yat-sen University (1)
United States (4) · China (3) · Belgium (1) · Egypt (1) · France (1) · Greece (1) · Turkey (Türkiye) (1)
Emmanuel Eric Pazo (2) · Constantine Georgakopoulos, MD, Phd (1) · Heleen Delbeke, MD (1) · Mae O Gordon, PhD (1) · Nadide Koca (1) · Penny Asbell, MD, MBA, FACS (1) · Sean Gratton, MD (1) · Stephen C. Pflugfelder, MD (1)
PMID 11237914, PMID 12649304, PMID 12823990, PMID 15161834, PMID 15286669, PMID 15832184, PMID 20973888, PMID 23445780, PMID 23665202, PMID 25179431, PMID 27119078, PMID 27294831, PMID 27929721, PMID 28190580, PMID 28280298, PMID 28319106, PMID 28475124, PMID 29075094, PMID 29671255, PMID 29731019, PMID 31518657, PMID 31800960, PMID 31834617, PMID 32280196, PMID 9778415, PMID 29799915, PMID 33973917, PMID 35049373, PMID 36749104, PMID 38087329, PMID 40839332