7 completed, 2 terminated, 2 withdrawn. 11 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 7, Terminated 2, Withdrawn 2 |
| Phase 2 | 2 | Terminated 1, Withdrawn 1 |
Follow Adrucil: new trials by email Literature Review of Adrucil trials Research Report on Adrucil
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Anti-CEA CAR-T + Chemotherapy VS Chemotherapy Alone in Patients With CEA+Pancreatic Cancer & Liver Metastases Anti-CEA CAR-T cells, gemcitabine/nab paclitaxel, NLIR+FU/FA - Malignant Tumor of Pancreas Metastatic to Liver | Phase 2 / Phase 3 | Withdrawn | Sorrento Therapeutics, Inc. | 2021-11-01 | 2022-04-01 | |
| Efficacy and Safety of Olaparib (MK-7339) With or Without Bevacizumab Compared to Bevacizumab With a Fluoropyrimidine in Unresectable or Metastatic Colorectal Cancer (CRC) (MK-7339-003/LYNK-003) Olaparib, 5-FU, Bevacizumab - Metastatic Colorectal Cancer | Phase 3 | Completed | Merck Sharp & Dohme LLC | 335 | 2020-08-19 | 2024-10-29 |
| A Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal Cancer Napabucasin, Fluorouracil, Leucovorin - Colorectal Cancer | Phase 3 | Completed | Sumitomo Pharma America, Inc. | 1253 | 2016-06-01 | 2023-11-15 |
| Phase 3 Study of FOLFIRINOX (mFFX) +/- SBRT in Locally Advanced Pancreatic Cancer Oxaliplatin, Irinotecan, Leucovorin - Pancreatic Cancer | Phase 3 | Completed | Stanford University | 27 | 2013-08-14 | 2022-10-28 |
| Transarterial Chemoembolization vs CyberKnife for Recurrent Hepatocellular Carcinoma CyberKnife, TACE, CT Contrast - Carcinoma, Hepatocellular | Phase 3 | Withdrawn | Albert Koong | 2011-02-01 | 2012-06-11 | |
| Combination Chemotherapy and Bevacizumab in Treating Patients With Advanced Neuroendocrine Tumors bevacizumab, 5-fluorouracil, leucovorin - Gastrointestinal Carcinoid Tumor, Islet Cell Tumor | Phase 2 / Phase 3 | Terminated | University of California, San Francisco | 36 | 2005-06-08 | 2023-05-22 |
| Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal Cancer Radiotherapy, Fluorouracil, Leucovorin Calcium - Rectal Mucinous Adenocarcinoma, Rectal Signet Ring Cell Adenocarcinoma | Phase 3 | Completed | National Cancer Institute (NCI) | 225 | 2003-10-15 | 2018-12-04 |
| FAC Versus FAC Plus Weekly Paclitaxel as Adjuvant Treatment of Node Negative High Risk Breast Cancer Patients Fluorouracil, Doxorubicin, Cyclophosphamide - Breast Cancer | Phase 3 | Completed | Spanish Breast Cancer Research Group | 1925 | 2003-09-19 | 2023-03-07 |
| Randomized Clinical Trial to Evaluate the Predictive Accuracy of a Gene Expression for Stage I-II Breast Cancer 5-Fluorouracil, Cyclophosphamide, Doxorubicin - Breast Cancer | Phase 3 | Completed | M.D. Anderson Cancer Center | 273 | 2003-09-01 | 2012-02-14 |
| Docetaxel, Doxorubicin (A), Cyclophosphamide (C) (TAC) vs 5-Fluorouracil, A, C (5FAC) Breast Cancer Adjuvant Treatment Docetaxel, 5-fluorouracil, Doxorubicin - Breast Neoplasms | Phase 3 | Completed | Spanish Breast Cancer Research Group | 1060 | 1999-07-01 | 2023-04-04 |
| Perioperative Chemotherapy in Treating Patients With Colon Cancer That Can Be Surgically Removed fluorouracil, leucovorin calcium - Colorectal Cancer | Phase 3 | Terminated | ECOG-ACRIN Cancer Research Group | 859 | 1993-10-01 | 2023-06-28 |
Breast Neoplasms (3) · Colorectal Neoplasms (3) · Neoplasms (2) · Adenoma, Islet Cell (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Islet Cell (1) · Colonic Diseases (1) · Colonic Neoplasms (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Gastrinoma (1) · Gastrointestinal Diseases (1) · Gastrointestinal Neoplasms (1) · Glucagonoma (1) · Insulinoma (1)
Spanish Breast Cancer Research Group (2) · Albert Koong (1) · ECOG-ACRIN Cancer Research Group (1) · M.D. Anderson Cancer Center (1) · Merck Sharp & Dohme LLC (1) · National Cancer Institute (NCI) (1) · Sorrento Therapeutics, Inc. (1) · Stanford University (1) · Sumitomo Pharma America, Inc. (1) · University of California, San Francisco (1)
United States (8) · Spain (5) · Canada (3) · Australia (2) · Belgium (2) · France (2) · Germany (2) · Japan (2) · South Korea (2) · Chile (1) · China (1) · Colombia (1) · Czechia (1) · Hong Kong (1) · Hungary (1)
Al Benson (1) · Albert Koong (1) · Daniel T Chang (1) · Emily K. Bergsland, MD (1) · Lajos Pusztai, MD (1) · Mary M. Kemeny, MD, FACS (1) · Ying Yan, MD MS (1)
PMID 40207789, PMID 21121833, PMID 21422418, PMID 23733779, PMID 34779646, PMID 38749110, PMID 41397917, PMID 42859303
2005 (1), 2016 (1), 2019 (1), U10CA021115 (1), U10CA023318 (1)