15 completed, 5 unknown, 2 recruiting, 1 not yet recruiting. 16 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 16 | Completed 9, Unknown 4, Recruiting 2, Not yet recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Adenotonsillectomy: new trials by email Literature Review of Adenotonsillectomy trials Research Report on Adenotonsillectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Adenoidectomy on Symptoms and IgE Levels in Children With AR Drug therapy (NASONEX nasal spray), Adenoidectomy, Adenotonsillectomy - Adenoidectomy, Tonsillectomy | Not applicable | Not yet recruiting | Tongji Hospital | 36 | 2026-04-11 | 2026-04-14 |
| Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils DISE-Directed Surgery, Adenotonsillectomy - Otolaryngological Disease, Obstructive Sleep Apnea | Not applicable | Recruiting | Oregon Health and Science University | 175 | 2024-10-04 | 2026-07-06 |
| Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS) DISE-Directed Surgery, Adenotonsillectomy - Obstructive Sleep Apnea, Down Syndrome | Not applicable | Recruiting | Oregon Health and Science University | 304 | 2023-08-02 | 2026-09-11 |
| Effect of Adenotonsillectomy on Velopharyngeal Valve Mechanism adenotonsillectomy, adenoidectomy, tonsillectomy - Velopharyngeal Insufficiency | Not applicable | Unknown | Assiut University | 200 | 2023-02-14 | 2023-04-19 |
| Oral Corticosteroids' Role in Pediatric Obstructive Sleep Apnea Adenotonsillectomy, Prednisolone - Pediatric Obstructive Sleep Apnea | Not applicable | Completed | Hotel Dieu de France Hospital | 87 | 2022-12-09 | 2025-04-17 |
| Brain Changes in Pediatric OSA Adenotonsillectomy - Pediatric Obstructive Sleep Apnea | Not applicable | Completed | University of California, Los Angeles | 56 | 2022-05-14 | 2024-11-29 |
| Surgical Treatment of Children With OSA and Small Tonsils or Down Syndrome Adenotonsillectomy, Drug-induced sleep endoscopy directed surgery - Obstructive Sleep Apnea of Child | Completed | Oregon Health and Science University | 30 | 2021-11-09 | 2025-09-29 | |
| Changes in Polysomnography and Rhinomanometry Parameters After Rapid Maxillary Expansion or Adenotonsilectomy in Children With Obstructive Sleep Apnea Adenotonsillectomy, Rapid maxillary expansion - Obstructive Sleep Apnea (OSA), Rapid Maxillary Expansion | Not applicable | Completed | Federal University of Minas Gerais | 51 | 2021-02-15 | 2025-07-16 |
| The Interplay Between Obstructive Sleep Apnea Cognitive Dysfunction in Pediatric Patients adenotonsillectomy, Lifestyle intervention - Obstructive Sleep Apnea | Not applicable | Completed | Al-Azhar University | 224 | 2020-11-07 | 2022-06-16 |
| Evaluation of the Functional Impact of Adenotonsilectomy Adenotonsillectomy - Apnea, Obstructive, Tonsillitis | Completed | Instituto de Ciências Biomédicas Abel Salazar | 78 | 2020-08-20 | 2022-09-08 | |
| Brain Tissue Integrity and Autonomic Function Alterations in Childhood OSA and ADHD, and After Adenotonsillectomy. Sleep and healthy lifestyle education, Other supportive care, Adenotonsillectomy - Attention-deficit/Hyperactivity Disorder, Autonomic Nervous System Imbalance | Not applicable | Unknown | Chang Gung Memorial Hospital | 100 | 2020-08-01 | 2021-02-01 |
| Sufentanil on Anesthesia Introduction and Recovery Quality in Pediatric Adenotonsillectomy Sufentanil Injection - Sufentanil | Not applicable | Completed | Tongji Hospital | 90 | 2020-07-06 | 2023-01-10 |
| Healthy Sleep for Children With Down Syndrome Adenotonsillectomy - Down Syndrome, Sleep Disordered Breathing | Completed | Brigham and Women's Hospital | 26 | 2019-05-22 | 2022-03-02 | |
| Adeno-tonsillectomy in Treatment of Obstructive Sleep Apnea adenotonsillectomy - Obstructive Sleep Disordered Breathing | Unknown | Assiut University | 60 | 2018-04-01 | 2019-01-23 | |
| Parent-QoL and Sleep Disordered Breathing adenotonsillectomy - Sleep Apnea Syndromes | Completed | Western Galilee Hospital-Nahariya | 45 | 2018-01-01 | 2023-04-26 | |
| Maxillary Expansion Effects in Children With Upper Airway Obstruction Rapid maxillary expansion, Adenotonsillectomy - Airway Obstruction | Not applicable | Unknown | Universidade Federal de Goias | 60 | 2017-07-13 | 2019-10-16 |
| Sleep Disordered Breathing, Adenotonsillectomy, Cognition and Pre-school Age Children Adenotonsillectomy, Watchful waiting with supportive care - Sleep Disordered Breathing | Not applicable | Completed | South Tees Hospitals NHS Foundation Trust | 4 | 2016-12-01 | 2018-05-02 |
| Surgical Versus Nonsurgical Treatment on Quality of Life for Children With Controversial OSA Diagnoses adenotonsillectomy, Nonsurgical management - Obstructive Sleep Apnea of Child | Not applicable | Unknown | Beijing Tongren Hospital | 60 | 2016-01-01 | 2017-12-14 |
| Follow-up Studies of Primary Snoring(PS) and Obstructive Sleep Apnea Hypopnea Syndrome(OSAHS) in Chinese Children Adenotonsillectomy, Conservative treatment, no treatment - Obstructive Sleep Apnea Syndrome | Completed | Beijing Children's Hospital | 500 | 2014-11-01 | 2022-07-21 | |
| Maxillary Expansion Treatment of Pediatric OSA Maxillary expansion, Adenotonsillectomy - Obstructive Sleep Apnea | Not applicable | Completed | University of British Columbia | 14 | 2013-05-01 | 2022-11-22 |
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Sleep Apnea, Obstructive (11) · Sleep Apnea Syndromes (4) · Down Syndrome (3) · Airway Obstruction (1) · Attention Deficit Disorder with Hyperactivity (1) · Infections (1) · Otorhinolaryngologic Diseases (1) · Respiratory Aspiration (1) · Respiratory Insufficiency (1) · Rhinitis, Allergic (1) · Tonsillitis (1) · Velopharyngeal Insufficiency (1)
Oregon Health and Science University (3) · Assiut University (2) · Tongji Hospital (2) · Al-Azhar University (1) · Beijing Children's Hospital (1) · Beijing Tongren Hospital (1) · Brigham and Women's Hospital (1) · Chang Gung Memorial Hospital (1) · Eastern Virginia Medical School (1) · Federal University of Minas Gerais (1) · Hotel Dieu de France Hospital (1) · Instituto de Ciências Biomédicas Abel Salazar (1) · Karolinska University Hospital (1) · South Tees Hospitals NHS Foundation Trust (1) · Universidade Federal de Goias (1)
United States (6) · China (4) · Egypt (3) · Brazil (2) · Canada (1) · Israel (1) · Italy (1) · Lebanon (1) · Portugal (1) · Sweden (1) · Taiwan (1) · United Kingdom (1)
Aijun XU, Dr. (1) · Benjamin Pliska, DDS (1) · Cristina M. Baldassari, MD (1) · Danielle Friberg, MD, PhD (1) · Demin Han, Prof. (1) · Derek J Lam, MD (1) · Derek Lam, MD (1) · Derek Lam, MD, MPH (1) · Francesco Violi, MD (1) · Jose Valladares Neto, PHD (1) · Li-Ang Lee, M.D., M.Sc. (1) · Mahmoud Aly Ragae, Lecturer (1) · Marzia Duse, MD (1) · Michael R Tremlett, BM, FRCA (1)
PMID 10889473, PMID 16735907, PMID 17118282, PMID 18312869, PMID 21521626, PMID 23110961, PMID 23692173, PMID 25601979, PMID 25805361, PMID 26465274, PMID 26700255, PMID 29267958, PMID 30269047, PMID 31375615, PMID 31377901, PMID 32347984, PMID 34194586
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