10 completed, 2 terminated, 1 enrolling by invitation, 1 not yet recruiting. 9 Phase 4, 3 Not applicable, 3 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 9 | Completed 6, Recruiting 1, Terminated 1, Withdrawn 1 |
| Not applicable | 3 | Enrolling by invitation 1, Terminated 1, Unknown 1 |
| Phase 2 | 3 | Completed 3 |
| Phase 1 | 1 | Not yet recruiting 1 |
Follow Adderall: new trials by email Literature Review of Adderall trials Research Report on Adderall
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Stimulant Medications in PTSD Placebo, Adderall - Adderall, PTSD | Phase 1 | Not yet recruiting | University of Chicago | 40 | 2026-09-15 | 2026-06-24 |
| Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes Testosterone Enanthate, Testosterone Cypionate, Testosterone Propionate - Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes | Not applicable | Enrolling by invitation | Enhanced Emirates Limited | 60 | 2026-03-12 | 2026-05-06 |
| The Role of Expectancy for Cognitive Enhancement in College Students Using Prescription Stimulants Nonmedically Adderall 10Mg Tablet, Placebo - Prescription Stimulants, Expectations | Phase 4 | Withdrawn | University of Alabama at Birmingham | 2025-07-01 | 2025-04-07 | |
| Addressing Cognitive Fog in Long-COVID-19 Patients Digital cognitive behavioral intervention-RxWell, Amphetamine-Dextroamphetamine - Cognitive Impairment, Long COVID | Phase 4 | Terminated | Eva Szigethy | 7 | 2023-04-04 | 2024-07-22 |
| Stimulant Medication Effects on Auditory Sensitivity in Teens With ADHD ADHD stimulants, for example, amphetamine, dexmethylphenidate, dextroamphetamine, methylphenidate - Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder | Completed | Nemours Children's Clinic | 70 | 2020-09-13 | 2022-12-13 | |
| Brain Indices of Stimulant Treatment in Drug-Naive Youth at Risk for Substance Use Disorder Adderall - Attention Deficit Disorder With Hyperactivity, Conduct Disorder | Phase 4 | Completed | Jeffrey Newcorn | 33 | 2019-11-05 | 2024-08-29 |
| Modafinil Versus Amphetamines for the Treatment of Narcolepsy Type 2 and Idiopathic Hypersomnia Modafinil, Amphetamine-Dextroamphetamine - Idiopathic Hypersomnia, Narcolepsy Without Cataplexy | Phase 2 | Completed | Emory University | 44 | 2019-04-15 | 2024-05-23 |
| Neuroimaging the Expectancy Versus Pharmacotherapy Effect of Adderall on Cognitive Performance Adderall, Placebo - Expectancy Versus Pharmacotherapy Effect of Adderall | Phase 4 | Completed | University of Alabama at Birmingham | 4 | 2018-11-10 | 2019-12-16 |
| Stimulant Effects on Disruptive Behavior Stimulant - Attention Deficit Hyperactivity Disorder, Problem Behavior | Phase 4 | Recruiting | Matthew J O'Brien, PhD, BCBA-D | 10 | 2018-10-01 | 2025-03-17 |
| Cardiovascular Effects of Adderall in Healthy Adults. Adderall capsule, Placebo capsule - Hemodynamics, Cardiovascular System | Phase 4 | Completed | Mayo Clinic | 30 | 2018-06-01 | 2025-01-14 |
| Dextroamphetamine and tDCS to Improve the Fluency Dexedrine, Active tDCS, Speech Therapy - Stroke | Phase 2 | Completed | The University of Texas Health Science Center, Houston | 10 | 2015-03-01 | 2018-08-03 |
| Omega-3 Supplementation to ADHD Medication in Children Omega-3 Fatty Acid, ADHD Medication - Attention Deficit Hyperactivity Disorder, Deficient Emotional Self-Regulation | Phase 4 | Completed | Massachusetts General Hospital | 21 | 2014-07-01 | 2017-06-29 |
| Follow up Treatment of Children With Attention Deficit Hyperactivity Disorder (ADHD) Academic and Organization skills, Parent Training, Social Skills Training - Attention Deficit Hyperactivity Disorder (ADHD) | Not applicable | Unknown | McGill University Health Centre/Research Institute of the McGill University Health Centre | 326 | 2012-12-01 | 2018-08-28 |
| Omega-3 Fatty Acid Supplementation to ADHD Pharmacotherapy in ADHD Adults With Deficient Emotional Self-Regulation Traits ADHD Medication, Omega-3 Fatty Acids - Attention Deficit Hyperactivity Disorder (ADHD), Deficient Emotional Self-Regulation (DESR) | Phase 2 | Completed | Massachusetts General Hospital | 2 | 2012-02-01 | 2018-10-23 |
| Stimulant Enhancement of Well-Being Therapy for Depression Amphetamine/dextroamphetamine, Placebo, Well-being therapy - Major Depressive Disorder | Not applicable | Terminated | Massachusetts General Hospital | 5 | 2012-02-01 | 2017-04-26 |
| Adjunctive Mixed Salts Amphetamine for Depressed Adults With Incomplete Response to Current Antidepressant Therapy mixed salts amphetamine - Major Depressive Disorder | Phase 4 | Completed | Rush University Medical Center | 41 | 2010-12-01 | 2023-06-15 |
| A Within-Subject Cross-Over Comparison Between Immediate Release and Extended Release Adderall Adderall ® Immediate Release, Adderall XR ® - Attention Deficit Hyperactivity Disorder | Phase 4 | Completed | NYU Langone Health | 62 | 2007-08-01 | 2016-06-02 |
Attention Deficit Disorder with Hyperactivity (7) · Depressive Disorder, Major (2) · Cognitive Dysfunction (1) · Conduct Disorder (1) · Deception (1) · Depression (1) · Idiopathic Hypersomnia (1) · Post-Acute COVID-19 Syndrome (1) · Problem Behavior (1) · Stress Disorders, Post-Traumatic (1) · Stroke (1) · Substance-Related Disorders (1)
Massachusetts General Hospital (3) · University of Alabama at Birmingham (2) · Emory University (1) · Enhanced Emirates Limited (1) · Eva Szigethy (1) · Jeffrey Newcorn (1) · Matthew J O'Brien, PhD, BCBA-D (1) · Mayo Clinic (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · NYU Langone Health (1) · Nemours Children's Clinic (1) · Rush University Medical Center (1) · The University of Texas Health Science Center, Houston (1) · University of Chicago (1)
United States (14) · Canada (1) · United Arab Emirates (1)
Anna Svatikova, MD (1) · Corey N Goldstein, MD (1) · Craig Surman, MD (1) · David Knight, PhD (1) · Eva Szigethy, MD, PhD (1) · Gerard E Francisco, MD (1) · Iliyan Ivanov, MD (1) · Jeffrey Newcorn, MD (1) · Karen Cropsey, Psy.D. (1) · Karen Cropsey, PsyD (1) · Kyoko Nagao, PhD (1) · Lenard Adler, MD (1) · Lily Hechtman, MD, FRCPC (1) · Lynn Marie Trotti, MD, MSc (1) · Matthew J O'Brien, PhD (1)
PMID 21904088, PMID 36913518, PMID 39306601, PMID 41770187
R21DA046029 (1)