53 completed, 28 unknown, 21 recruiting, 9 not yet recruiting. 115 Not applicable, 6 Phase 2, 2 Early Phase 1, 2 Phase 1, 2 Phase 4.
Follow Active tDCS: new trials by email Literature Review of Active tDCS trials Research Report on Active tDCS
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After Surgery Dex-Esk, Placebo, Active tDCS - Older Patients, Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 1996 | 2026-10-01 | 2026-10-13 |
| Dexmedetomidine-esketamine and tDCS for Prevention of Neurocognitive Complications After Surgery Dex-Esk, Placebo, Active tDCS - Older Patients, Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 1996 | 2026-10-01 | 2026-10-13 |
| Effects of Transcranial Direct Current Stimulation Combined With Virtual Reality on Gait and Self-Esteem in Children With Spastic Cerebral Palsy Active Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation, Virtual Reality Rehabilitation - Spastic Diplegic Cerebral Palsy | Not applicable | Recruiting | Riphah International University | 42 | 2026-09-15 | 2026-09-23 |
| The Effect of Combined Brain Stimulation and Exercise for Improving Cognitive Function in Schizophrenia Aerobic exercise, Active tDCS, Sham tDCS - Schizophrenia, Cognitive Functions | Not applicable | Not yet recruiting | The Hong Kong Polytechnic University | 66 | 2026-09-01 | 2026-08-04 |
| Clustered tDCS Sessions for Reducing Alcohol Consumption in Non-abstinent Patients With Alcohol Use Disorder Active tDCS, Placebo tDCS - Chronic Alcohol Use Disorder | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire Dijon | 312 | 2026-04-01 | 2026-03-02 |
| Transcranial Direct Current Stimulation in Children With Autism Active tDCS, Sham (No Treatment) - Autism Spectrum Disorder, Executive Dysfunction | Not applicable | Recruiting | New York State Institute for Basic Research | 24 | 2026-04-01 | 2026-02-23 |
| Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms Active tDCS, Sham tDCS - Persistent Post Concussion Syndrome, Mild Traumatic Brain Injury | Not applicable | Recruiting | University of Minnesota | 30 | 2026-03-05 | 2026-09-01 |
| Effectiveness of Exercise Alone and tDCS+Exercise on Cognitive Function Improvement in Patients With Treatment Resistant Schizophrenia Aerobic Exercise, Stretching/Education Control, Active tDCS - Schizophrenia, Treatment Resistant Schizophrenia | Not applicable | Not yet recruiting | Kit Wa Chan | 160 | 2026-02-23 | 2026-02-11 |
| The Added Value of Transcranial Direct Current Stimulation (tDCS) During Exercise for People With Chronic Widespread Pain Active tDCS, Aerobic exercise, Sham tDCS - Chronic Widespread Pain, Fibromyalgia (FM) | Not applicable | Recruiting | Vrije Universiteit Brussel | 120 | 2026-02-01 | 2026-04-20 |
| Effect of Early Neuromodulation Coupled With Rehabilitation on the Prevention of Post-stroke Pain Active tDCS, Sham tDCS - Stroke, Neuropathic Pain | Not applicable | Not yet recruiting | University Hospital, Clermont-Ferrand | 60 | 2026-01-01 | 2025-12-23 |
| The Effect of Combined Brain Stimulation and Yoga for Improving Cognitive Function in Psychosis Active tDCS, Sham tDCS, Yoga - Cognitive Functioning, Psychosis | Not applicable | Recruiting | The Hong Kong Polytechnic University | 135 | 2026-01-01 | 2026-08-05 |
| The Use of tDCS for Vaping Reduction Active tDCS, Sham tDCS - Vaping, Addiction | Not applicable | Recruiting | Centre for Addiction and Mental Health | 40 | 2026-01-01 | 2026-03-19 |
| Evaluation of the Efficacy of Neuromodulation in the Control of Chronic Orofacial Pain Active Neuromodulation (tDCS or TMS), Sham Neuromodulation (tDCS or TMS) - Orofacial Pain | Not applicable | Enrolling by invitation | Egas Moniz - Cooperativa de Ensino Superior, CRL | 50 | 2025-11-01 | 2026-02-20 |
| Effects of tDCS on Cognitive Flexibility and EEG Oscillations in Orthorexia Nervosa Active tDCS, Sham tDCS - Orthorexia Nervosa | Not applicable | Recruiting | Istanbul Medipol University Hospital | 48 | 2025-11-01 | 2026-04-01 |
| tDCS for Cancer-Related Fatigue and Weakness Active tDCS + elbow flexion exercise, Sham tDCS + elbow flexion exercise - Cancer-related Fatigue, Neuromodulation | Early Phase 1 | Not yet recruiting | Kessler Foundation | 75 | 2025-09-10 | 2025-09-08 |
| tDCS Intervention in Breast Cancer Survivors With and Without Obesity Reporting Cognitive Impairment active tDCS, sham tDCS - Breast Cancer Survivor, Obesity, Overweight | Not applicable | Recruiting | University of Helsinki | 40 | 2025-09-01 | 2025-09-02 |
| Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosis (MS) Active tDCS, Sham tDCS - Multiple Sclerosis, Depression | Phase 2 | Recruiting | NYU Langone Health | 170 | 2025-08-11 | 2026-06-29 |
| Non-invasive Brain Stimulation in Subjects with Major Depressive Disorder Active tDCS, Sham treatment - Major Depressive Disorder (MDD) | Not applicable | Not yet recruiting | Carmen Concerto | 105 | 2025-01-02 | 2024-12-03 |
| Neuromodulation Effects in Older Adults Active tDCS, Sham tDCS - Cognitive Impairment, Cognitive Decline | Not applicable | Withdrawn | University of Florida | 2024-12-01 | 2024-11-21 | |
| Effect of Transcranial Direct Current Stimulation on Postoperative Delirium in Elderly Patients active tDCS, sham tDCS - Delirium - Postoperative, Hip Fractures (ICD-10 72.01-72.2) | Not applicable | Recruiting | Huazhong University of Science and Technology | 160 | 2024-11-01 | 2025-04-06 |
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Schizophrenia (10) · Depression (8) · Stroke (8) · Cognitive Dysfunction (7) · Parkinson Disease (7) · Chronic Pain (5) · Depressive Disorder, Major (5) · Alzheimer Disease (4) · Anxiety Disorders (4) · Multiple Sclerosis (4) · Aphasia, Primary Progressive (3) · Behavior, Addictive (3) · Fibromyalgia (3) · Hallucinations (3) · Psychotic Disorders (3)
Centre for Addiction and Mental Health (7) · University of Minnesota (7) · The University of Texas Health Science Center, Houston (6) · NYU Langone Health (5) · Federal University of Paraíba (4) · Hospital de Clinicas de Porto Alegre (4) · Centre Hospitalier Universitaire Dijon (3) · University of Michigan (3) · Bambino Gesù Hospital and Research Institute (2) · Butler Hospital (2) · Centre Hospitalier Universitaire de Besancon (2) · Florida State University (2) · Hôpital le Vinatier (2) · IRCCS Centro San Giovanni di Dio Fatebenefratelli (2) · Istanbul Medipol University Hospital (2)
United States (45) · Brazil (12) · France (11) · Canada (10) · Italy (6) · China (5) · Turkey (Türkiye) (5) · Belgium (4) · Hong Kong (3) · Germany (2) · Israel (2) · Portugal (2) · Switzerland (2) · Taiwan (2) · United Kingdom (2)
Leigh Charvet, MD (3) · Adriana B Conforto, MD Phd (2) · Aprinda I Queen, PhD (2) · Dong-Xin Wang, MD, PhD (2) · Jazmin Camchong, PhD (2) · Nir Giladi, M.D (2) · Philip Gerretsen, MD, PhD (2) · Sven Vanneste, PhD (2) · A.J Stoessl, MD (1) · Abrantes Abrantes, Ph.D. (1) · Adriana Conforto, MD PhD (1) · Alexandre Haroche, MD,PHD (1) · Alexandru Iordan, PhD (1) · Ali Moghimi, PhD (1)
PMID 11971088, PMID 12114001, PMID 12604786, PMID 12803972, PMID 15999258, PMID 16045502, PMID 16352500, PMID 17050709, PMID 17452283, PMID 18096677, PMID 18525028, PMID 19064743, PMID 19753097, PMID 20395612, PMID 21068427, PMID 21173250, PMID 21197418, PMID 21320389, PMID 21462081, PMID 21477637, PMID 21631313, PMID 21780073, PMID 21950776, PMID 21980313, PMID 22032743, PMID 22820638, PMID 24332532, PMID 30580246, PMID 31461371, PMID 32006627, PMID 33175411, PMID 9482939, PMID 10990547, PMID 11837526, PMID 11994754, PMID 12395559, PMID 12807923, PMID 15905749, PMID 15978929, PMID 16427357, PMID 16467613, PMID 16541455, PMID 16554525, PMID 16876549, PMID 16926202, PMID 16982502, PMID 17444810, PMID 17611240, PMID 17678656, PMID 18383072
R15NR018050 (2), 2014 (1), 4UH3DA047793 (1), K01HD078484 (1), K25AG086592 (1), P2CHD086844 (1), R01CA239630 (1), R01DK131050 (1), R21AA021201 (1), R21AG060444 (1), R21MH102539 (1), R43NS077652 (1)