8 completed, 4 recruiting, 2 unknown. 7 Phase 4, 4 Not applicable, 3 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 7 | Completed 5, Recruiting 1, Unknown 1 |
| Not applicable | 4 | Completed 2, Recruiting 1, Unknown 1 |
| Phase 2 | 3 | Recruiting 2, Completed 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow 0.9%sodium chloride: new trials by email Literature Review of 0.9%sodium chloride trials Research Report on 0.9%sodium chloride
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pre-emptive Analgesia Using Nebulized Ketamine Versus Nebulized Dexmedetomidine in Endoscopic Nasal Surgeries Dexmedetomidine, Ketamine, 0.9%sodium chloride - Nose Diseases | Not applicable | Recruiting | Sohag University | 105 | 2025-04-14 | 2025-07-09 |
| The Effect of Local Application of Tranexamic Acid Versus Placebo on Postoperative Complications in Plastic Surgery Tranexamic Acid 100 MG/ML, 0.9%sodium chloride - Surgical Complication | Phase 4 | Recruiting | St. Olavs Hospital | 3000 | 2024-09-18 | 2026-08-14 |
| Erector Spinae Plane Block for Cervical Spine Surgery 0.9%sodium chloride, 0.2% ropivacaine - Spine Fusion, Spine Disease | Phase 4 | Completed | Poznan University of Medical Sciences | 60 | 2024-07-15 | 2026-02-02 |
| Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Hip Arthroplasty 0.9%sodium chloride, Dexamethasone, Dexmedetomidine - Hip Osteoarthritis, Hip Arthropathy | Phase 4 | Unknown | Poznan University of Medical Sciences | 30 | 2024-04-10 | 2024-04-29 |
| Dexamethasone vs. Dexmedetomidine for Popliteal Nerve Block in Pain Management After Pediatric Ankle and Foot Surgery 0.9%sodium chloride, Dexamethasone, Dexmedetomidine - Foot Injuries and Disorders, Ankle Injuries and Disorders | Phase 4 | Completed | Poznan University of Medical Sciences | 90 | 2024-02-09 | 2025-07-11 |
| Pericapsular Nerve Group Block Chemical Neurolysis in Advanced Hip Osteoarthritis 0.9%sodium chloride, 95% ethanol - Osteoarthritis, Osteoarthritis, Hip | Phase 4 | Completed | Poznan University of Medical Sciences | 100 | 2023-10-17 | 2025-01-21 |
| Intranasal Heparin Treatment to Reduce Transmission Among Household Contacts of COVID 19 Positive Adults and Children unfractionated heparin, 0.9%sodium chloride - COVID-19 | Phase 2 / Phase 3 | Completed | Murdoch Childrens Research Institute | 506 | 2023-01-30 | 2026-05-05 |
| Dexamethasone in the Prevention of Post-spinal Paralytic Ileus After Cesarean Section 0.9%sodium chloride, Dexamethasone - Postoperative Ileus | Phase 1 / Phase 2 | Recruiting | Assiut University | 90 | 2022-12-01 | 2024-12-02 |
| Effects of Continuous Dexmedetomidine Infusion on Systemic Microvascular Function in Laparoscopic Cholecystecthomy dexmedetomidine intravenous infusion, 0.9%sodium chloride - Laparoscopic Surgery | Not applicable | Completed | National Institute of Cardiology, Laranjeiras, Brazil | 64 | 2022-04-01 | 2025-12-03 |
| Nebulized Heparin for the Treatment of COVID-19 Heparin, 0.9%sodium chloride - Covid19, Pneumonia, Viral | Phase 4 | Completed | Frederick Health | 50 | 2021-02-22 | 2021-09-05 |
| Pain Management After Adductor Canal Block for Total Knee Arthroplasty Ropivacaine 0.2% Injectable Solution, 0.9%sodium chloride - Knee Osteoarthritis, Knee Arthritis | Phase 4 | Completed | Poznan University of Medical Sciences | 361 | 2020-06-18 | 2023-10-17 |
| Phase 2 Trial Using rhDNase to Reduce Mortality in COVID-19 Patients With Respiratory Failure Pulmozyme/ Recombinant human deoxyribonuclease (rh-DNase), 0.9%sodium chloride - Covid19 | Phase 2 | Recruiting | Jon Simmons | 44 | 2020-04-28 | 2021-05-28 |
| Shenqi Fuzheng Injection for the Treatment of Cancer-related Fatigue in Chemo Patients With Digestive Tract . shenqifuzheng, 0.9%sodium chloride - Digestive Tract | Not applicable | Unknown | Livzon Pharmaceutical Group Inc. | 270 | 2017-12-24 | 2018-03-06 |
| Balanced Crystalloid vs. Saline in Children With Septic Shock Balanced crystalloid solution, 0.9%sodium chloride - Septic Shock, Shock | Not applicable | Completed | All India Institute of Medical Sciences | 708 | 2017-04-01 | 2021-12-21 |
COVID-19 (3) · Osteoarthritis, Hip (2) · Acute Kidney Injury (1) · Agnosia (1) · Ankle Injuries (1) · Coronavirus Infections (1) · Disease (1) · Foot Injuries (1) · Nose Diseases (1) · Osteoarthritis (1) · Osteoarthritis, Knee (1) · Pneumonia, Viral (1) · Shock (1) · Shock, Septic (1) · Spinal Diseases (1)
Poznan University of Medical Sciences (5) · All India Institute of Medical Sciences (1) · Assiut University (1) · Frederick Health (1) · Jon Simmons (1) · Livzon Pharmaceutical Group Inc. (1) · Murdoch Childrens Research Institute (1) · National Institute of Cardiology, Laranjeiras, Brazil (1) · Sohag University (1) · St. Olavs Hospital (1)
Poland (5) · Egypt (2) · United States (2) · Australia (1) · Brazil (1) · China (1) · Denmark (1) · Finland (1) · India (1) · Norway (1)
Malgorzata Domagalska, Ph.D. (2) · Donald Campbell, MD (1) · Jhuma Sankar, MD Ped (1) · Katarzyna Wieczorowska-Tobis, Prof.dr hab (1) · Katarzyna Wieczorowska-Tobis, Prof.dr hab. (1) · Kjersti Ausen, MD PhD (1) · Paul Monagle, MD (1) · Rakesh Lodha, MD Ped (1) · Sushil K Kabra, MD Ped (1) · Tomasz Kotwicki, MD PhD (1)
PMID 24627001, PMID 35320968, PMID 35359478, PMID 37294145, PMID 38649069, PMID 40480912, PMID 41043950
2023 (1)