2 recruiting, 1 active not recruiting. 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Recruiting 2, Active not recruiting 1 |
Follow Xanthogranuloma, Juvenile: new trials by email Literature Review of Xanthogranuloma, Juvenile trials Research Report on Xanthogranuloma, Juvenile
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mirdametinib in Histiocytic Disorders Mirdametinib - Langerhans Cell Histiocytosis (LCH), Juvenile Xanthogranuloma (JXG) | Phase 2 | Recruiting | Children's Hospital Medical Center, Cincinnati | 40 | 2024-02-05 | 2026-09-21 |
| Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders Cobimetinib - Langerhan's Cell Histiocytosis, Juvenile Xanthogranuloma | Phase 2 | Recruiting | Carl Allen | 90 | 2021-04-19 | 2026-10-26 |
| Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration and Biopsy - Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Non-Hodgkin Lymphoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 1377 | 2017-07-31 | 2026-07-24 |
Histiocytosis, Langerhans-Cell (3) · Histiocytic Sarcoma (2) · Histiocytosis, Sinus (2) · Central Nervous System Neoplasms (1) · Ependymoma (1) · Erdheim-Chester Disease (1) · Glioma (1) · Hepatoblastoma (1) · Histiocytic Disorders, Malignant (1) · Lymphoma, Non-Hodgkin (1) · Medulloblastoma (1) · Neuroblastoma (1) · Neuroectodermal Tumors, Primitive, Peripheral (1) · Osteosarcoma (1)
Hemic and Lymphatic Diseases (3) · Histiocytosis (3) · Histiocytosis, Non-Langerhans-Cell (3) · Lung Diseases (3) · Lung Diseases, Interstitial (3) · Lymphatic Diseases (3) · Respiratory Tract Diseases (3) · Skin Diseases (3) · Skin and Connective Tissue Diseases (3) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Genetic Diseases, Inborn (1)
Biopsy (1) · LY3023414 (1) · Magnetic Resonance Spectroscopy (1) · Nuclear Medicine Department, Hospital (1) · Phantoms, Imaging (1) · Specimen Handling (1) · Vemurafenib (1) · X-Rays (1) · cobimetinib (1) · ensartinib (1) · erdafitinib (1) · ivosidenib (1) · larotrectinib (1) · mirdametinib (1) · olaparib (1)
Carl Allen (1) · Children's Hospital Medical Center, Cincinnati (1) · National Cancer Institute (NCI) (1)
United States (3) · Australia (1) · Canada (1) · Puerto Rico (1)
Allison Bartlett, MD (1) · Ashish Kumar, MD, PhD (1) · Carl E Allen, MD, PhD (1) · Donald W Parsons (1)
PMID 33591402, PMID 35353553, PMID 41166674, PMID 42686334
U10CA180886 (1)