3 active not recruiting, 3 recruiting, 1 suspended, 1 unknown. 5 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Active not recruiting 2, Recruiting 1, Suspended 1, Unknown 1 |
| Phase 1 | 2 | Active not recruiting 1, Recruiting 1 |
Follow Histiocytic Sarcoma: new trials by email Literature Review of Histiocytic Sarcoma trials Research Report on Histiocytic Sarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Q702 for the Treatment of Patients With Hematologic Malignancies Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, Bone Marrow Aspiration - Hematopoietic and Lymphatic System Neoplasm, Histiocytic Sarcoma | Phase 1 | Recruiting | Mayo Clinic | 46 | 2025-08-27 | 2025-10-10 |
| Histiocytic Disorder Follow-up Study Histiocytosis, Langerhans Cell Histiocytosis | Recruiting | University of Alabama at Birmingham | 6000 | 2022-09-01 | 2026-06-12 | |
| Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders Cobimetinib - Langerhan's Cell Histiocytosis, Juvenile Xanthogranuloma | Phase 2 | Recruiting | Carl Allen | 90 | 2021-04-19 | 2026-10-26 |
| Pembrolizumab in Neoplasms or Lymphomas Pembrolizumab - Lymphoma, Histiocytic Sarcoma | Phase 2 | Suspended | Dana-Farber Cancer Institute | 18 | 2017-12-07 | 2026-08-06 |
| Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration and Biopsy - Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Non-Hodgkin Lymphoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 1377 | 2017-07-31 | 2026-07-24 |
| Hypofractionated Radiotherapy With Sequential Chemotherapy in Marginally Resectable Soft Tissue Sarcomas of Extremities or Trunk Wall Sequential chemotherapy - 3 courses of AI, Hypofractionated radiotherapy - Sarcoma, Fibrosarcoma | Phase 2 | Unknown | Maria Sklodowska-Curie National Research Institute of Oncology | 46 | 2017-02-11 | 2021-01-22 |
| Lenalidomide for Adult Histiocyte Disorders Lenalidomide - Langerhans Cell Histiocytosis (LCH), Histiocytoses Erdheim-chester Disease | Phase 2 | Active not recruiting | Dana-Farber Cancer Institute | 12 | 2015-08-01 | 2026-07-23 |
| CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene Allodepleted T Cells - Acute Lymphoblastic Leukemia, Non-Hodgkin's Lymphoma | Phase 1 | Active not recruiting | Baylor College of Medicine | 10 | 2008-12-01 | 2026-07-01 |
Histiocytosis, Langerhans-Cell (5) · Erdheim-Chester Disease (4) · Dendritic Cell Sarcoma, Interdigitating (2) · Histiocytosis, Sinus (2) · Lymphoma, Non-Hodgkin (2) · Myelodysplastic Syndromes (2) · Sarcoma (2) · Xanthogranuloma, Juvenile (2) · Blastic Plasmacytoid Dendritic Cell Neoplasm (1) · Central Nervous System Neoplasms (1) · Dendritic Cell Sarcoma, Follicular (1) · Dermatofibrosarcoma (1) · Ependymoma (1) · Fibrosarcoma (1)
Hemic and Lymphatic Diseases (8) · Lymphatic Diseases (8) · Neoplasms (8) · Neoplasms by Histologic Type (8) · Histiocytic Disorders, Malignant (7) · Histiocytosis (7) · Histiocytosis, Non-Langerhans-Cell (6) · Lung Diseases (5) · Lung Diseases, Interstitial (5) · Respiratory Tract Diseases (5) · Immune System Diseases (4) · Immunoproliferative Disorders (4) · Lymphoma (3) · Lymphoproliferative Disorders (3) · Skin Diseases (3)
Biopsy (2) · Magnetic Resonance Spectroscopy (2) · Specimen Handling (2) · LY3023414 (1) · Lenalidomide (1) · Nuclear Medicine Department, Hospital (1) · Phantoms, Imaging (1) · Radiation Dose Hypofractionation (1) · Vemurafenib (1) · X-Rays (1) · cobimetinib (1) · ensartinib (1) · erdafitinib (1) · ivosidenib (1) · larotrectinib (1)
Dana-Farber Cancer Institute (2) · Baylor College of Medicine (1) · Carl Allen (1) · Maria Sklodowska-Curie National Research Institute of Oncology (1) · Mayo Clinic (1) · National Cancer Institute (NCI) (1) · University of Alabama at Birmingham (1)
United States (7) · Australia (1) · Canada (1) · Poland (1) · Puerto Rico (1)
Eric Jacobsen, MD (2) · Carl E Allen, MD, PhD (1) · Donald W Parsons (1) · Gaurav Goyal, MD (1) · Jithma P. Abeykoon, MD (1) · Malcolm K Brenner, MD (1)
PMID 22047558, PMID 24753538, PMID 26072403, PMID 26639404, PMID 32871584, PMID 33591402, PMID 35353553, PMID 41166674, PMID 42194972, PMID 42686334
U10CA180886 (1)