3 recruiting, 2 completed, 2 unknown, 1 terminated. 3 Phase 2, 3 Phase 3, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Unknown 2, Recruiting 1 |
| Phase 3 | 3 | Unknown 2, Completed 1 |
| Not applicable | 2 | Recruiting 1, Terminated 1 |
Follow West Syndrome: new trials by email Literature Review of West Syndrome trials Research Report on West Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multicentre Real-life Follow-up Study of Rare Epileptic Syndromes in Children and Adolescents Epilepsy, West Syndrome | Recruiting | Assistance Publique - Hôpitaux de Paris | 1000 | 2025-12-11 | 2026-02-24 | |
| A Study to Prevent Infantile Spasms Relapse Prednisolone, Famotidine, Placebo - Infantile Spasms, Infantile Epileptic Spasms Syndrome | Phase 2 | Recruiting | University of California, Los Angeles | 40 | 2025-05-05 | 2025-05-08 |
| Cortical Excitability in West Syndrome Using Transcranial Magnetic Stimulation ACTH/Oral Steroids - West Syndrome | Phase 2 / Phase 3 | Unknown | All India Institute of Medical Sciences | 40 | 2024-03-01 | 2024-03-04 |
| Ketogenic Diet vs ACTH for the Treatment of Children With West Syndrome Ketogenic diet, ACTH - Ketogenic Diet, West Syndrome | Phase 2 / Phase 3 | Unknown | All India Institute of Medical Sciences | 80 | 2022-04-18 | 2024-06-25 |
| Vigabatrin With High Dose Prednisolone Combination Therapy vs Vigabatrin Alone for Infantile Spasm Combination therapy with vigabatrin and prednisolone, Vigabatrin Tablets - Infantile Spasm, West Syndrome | Not applicable | Recruiting | Kullasate Sakpichaisakul | 250 | 2020-05-18 | 2021-08-25 |
| Prednisolone in Infantile Spasms- High Dose Versus Usual Dose Oral prednisolone - Infantile Spasms, West Syndrome | Phase 3 | Completed | Lady Hardinge Medical College | 63 | 2012-02-01 | 2013-04-09 |
| Prevention of West Syndrome With Low-dose Adrenocorticotropin Hormone (ACTH) adrenocorticotropin hormone - West Syndrome | Not applicable | Terminated | Ann & Robert H Lurie Children's Hospital of Chicago | 6 | 2011-07-01 | 2026-09-09 |
| Molecular Genetics in Infantile Spasms Infantile Spasms, West Syndrome | Completed | Hospices Civils de Lyon | 41 | 2010-10-01 | 2016-08-31 |
Spasms, Infantile (8) · Epilepsies, Myoclonic (1) · Epilepsy (1) · Recurrence (1)
Brain Diseases (8) · Central Nervous System Diseases (8) · Epilepsy, Generalized (8) · Epileptic Syndromes (8) · Nervous System Diseases (8) · Epilepsy (7) · Disease Attributes (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
Prednisolone (3) · Adrenocorticotropic Hormone (1) · Combined Modality Therapy (1) · Diet Therapy (1) · Diet, Ketogenic (1) · Famotidine (1) · Vigabatrin (1)
All India Institute of Medical Sciences (2) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Assistance Publique - Hôpitaux de Paris (1) · Hospices Civils de Lyon (1) · Kullasate Sakpichaisakul (1) · Lady Hardinge Medical College (1) · University of California, Los Angeles (1)
India (3) · United States (2) · France (1) · Thailand (1)
Doulgas R Nordli, Jr, MD (1) · John J. Millichap, MD (1) · Kullasate Sakpichaisakul, MD (1) · Satinder Aneja, MD (1) · Shaun A. Hussain, MD, MS (1) · Sheffali Gulati (1) · Sookyong Koh, MD, PhD (1)
PMID 10368073, PMID 10561962, PMID 10565592, PMID 11673582, PMID 12403260, PMID 14734931, PMID 15159460, PMID 15509243, PMID 15541450, PMID 18077226, PMID 20608959, PMID 21070215, PMID 22689735, PMID 22859699, PMID 24657009, PMID 25048310, PMID 26216500, PMID 26280806, PMID 26302697, PMID 27838190, PMID 29105055, PMID 29966811, PMID 40116235, PMID 4515986, PMID 6308515, PMID 6539199, PMID 8604274, PMID 8681895