2 active not recruiting, 2 not yet recruiting, 1 completed, 1 unknown. 6 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Active not recruiting 2, Not yet recruiting 2, Completed 1, Unknown 1 |
| Phase 1 | 1 | Not yet recruiting 1 |
Follow Vulvar Squamous Cell Carcinoma: new trials by email Literature Review of Vulvar Squamous Cell Carcinoma trials Research Report on Vulvar Squamous Cell Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sac-TMT in Vaginal and Vulvar Cancers Sacituzumab Tirumotecan (sac-TMT) - Vaginal Squamous Cell Carcinoma, Vulvar Squamous Cell Carcinoma | Phase 2 | Not yet recruiting | Latin American Cooperative Oncology Group | 48 | 2027-01-01 | 2026-09-04 |
| Safety and Efficacy of Nivolumab and Imiquimod Combination in Vulvar Squamous Cell Carcinoma Patients Imiquimod 5% cream, Nivolumab - Vulvar Squamous Cell Carcinoma | Phase 1 / Phase 2 | Not yet recruiting | Centre Leon Berard | 50 | 2026-09-01 | 2026-09-30 |
| Cisplatin+Pembrolizumab+RT in Vulvar Cancer Cisplatin, Pembrolizumab, Radiation Therapy - Vulvar Cancer, Vulvar Squamous Cell Carcinoma | Phase 2 | Active not recruiting | Massachusetts General Hospital | 24 | 2020-07-29 | 2026-05-05 |
| Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers Biopsy Procedure, Biospecimen Collection, Computed Tomography - Anaplastic Large Cell Lymphoma, ALK-Negative, Anaplastic Large Cell Lymphoma, ALK-Positive | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 68 | 2017-09-27 | 2026-08-13 |
| Radiation Therapy, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Locally Advanced Squamous Cell Cancer of the Vulva Cisplatin, Gemcitabine Hydrochloride, Intensity-Modulated Radiation Therapy - Stage III Vulvar Cancer AJCC v7, Stage IIIA Vulvar Cancer AJCC v7 | Phase 2 | Unknown | Gynecologic Oncology Group | 57 | 2012-07-02 | 2021-12-29 |
| Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Cancer of the Vulva 3-Dimensional Conformal Radiation Therapy, Cisplatin, Conventional Surgery - Stage III Vulvar Cancer, Stage IVB Vulvar Cancer | Phase 2 | Completed | Gynecologic Oncology Group | 61 | 2005-01-01 | 2017-11-20 |
Vulvar Neoplasms (3) · Adenocarcinoma, Papillary (1) · Carcinoma, Basal Cell (1) · Carcinoma, Basosquamous (1) · Carcinoma, Merkel Cell (1) · Carcinoma, Signet Ring Cell (1) · Eccrine Porocarcinoma (1) · Lymphoma, Large-Cell, Anaplastic (1) · Lymphoma, T-Cell (1) · Lymphoma, T-Cell, Cutaneous (1) · Microcystic adnexal carcinoma (1) · Muir-Torre Syndrome (1) · Mycosis Fungoides (1) · Paget Disease, Extramammary (1) · Sezary Syndrome (1)
Neoplasms (4) · Neoplasms by Site (4) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Genital Diseases (3) · Genital Diseases, Female (3) · Genital Neoplasms, Female (3) · Urogenital Diseases (3) · Urogenital Neoplasms (3) · Vulvar Diseases (3) · Adenocarcinoma (1) · Carcinoma (1) · Carcinoma, Neuroendocrine (1) · Colorectal Neoplasms, Hereditary Nonpolyposis (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1)
Cisplatin (3) · 1,2-diaminocyclohexaneplatinum II citrate (2) · Nivolumab (2) · Platinum (2) · Biopsy (1) · Gemcitabine (1) · Imiquimod (1) · Radiotherapy (1) · Radiotherapy, Conformal (1) · Radiotherapy, Intensity-Modulated (1) · Specimen Handling (1) · pembrolizumab (1) · talimogene laherparepvec (1)
Gynecologic Oncology Group (2) · Centre Leon Berard (1) · Latin American Cooperative Oncology Group (1) · Massachusetts General Hospital (1) · National Cancer Institute (NCI) (1)
United States (4) · Brazil (1) · France (1)
David Moore (1) · Fernando Cotait Maluf (1) · Neil S Horowitz (1) · Oladapo Yeku, MD, PHD (1)
U10CA027469 (2), U10CA180868 (1), UM1CA186709 (1), UM1CA186716 (1)