4 completed. 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 4 |
Follow Trypanosomiasis, African: new trials by email Literature Review of Trypanosomiasis, African trials Research Report on Trypanosomiasis, African
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DDI Study of Single Oral Dose of Acoziborole With Sequential Co-administration of Midazolam and Dextromethorphan Acoziborole, Midazolam, Dextromethorphan - Trypanosomiasis, African | Phase 1 | Completed | Drugs for Neglected Diseases | 20 | 2023-02-09 | 2023-07-17 |
| ADME Study of Acoziborole in Healthy Subjects [14C]-acoziborole capsule, 240 mg containing NMT 9.25 kBq (250 nCi) 14C - Trypanosomiases, African | Phase 1 | Completed | Drugs for Neglected Diseases | 6 | 2020-02-05 | 2021-04-27 |
| Bioequivalence Study - Reference Clinical Fexinidazole Tablet Versus Proposed Market Formulation Fexinidazole - Trypanosomiasis, African | Phase 1 | Completed | Drugs for Neglected Diseases | 30 | 2015-03-01 | 2015-10-08 |
| Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the SCYX-7158 SCYX-7158, Placebo - Trypanosomiasis, Trypanosomiasis, African | Phase 1 | Completed | Drugs for Neglected Diseases | 136 | 2012-02-01 | 2015-09-18 |
Neglected Diseases (1) · Parasitic Diseases (1) · Protozoan Infections (1) · Trypanosomiasis (1)
Euglenozoa Infections (4) · Infections (4) · Vector Borne Diseases (4) · Parasitic Diseases (3) · Protozoan Infections (3) · Trypanosomiasis (3) · Disease Attributes (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
Dextromethorphan (1) · Midazolam (1) · SCYX 7158 (1) · fexinidazole (1)
Drugs for Neglected Diseases (4)
France (2) · Malaysia (1) · United Kingdom (1)
Antoine Tarral, MD (2) · Sharan Sidhu, MBChB (1) · Sharon Ng Shi Min (1)