3 completed, 1 not yet recruiting, 1 recruiting, 1 terminated. 4 Phase 2, 2 Phase 1, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Not yet recruiting 1, Recruiting 1 |
| Phase 1 | 2 | Terminated 1, Withdrawn 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow Transplant-Related Hematologic Malignancy: new trials by email Literature Review of Transplant-Related Hematologic Malignancy trials Research Report on Transplant-Related Hematologic Malignancy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Menin-Inhibitor Targeted Maintenance in AML Revumenib, Placebo - Relapsed Adult AML, Stem Cell Transplant Complications | Phase 2 | Not yet recruiting | Center for International Blood and Marrow Transplant Research | 146 | 2026-12-01 | 2026-06-22 |
| GM-CSF With Post-Transplant Cyclophosphamide Sargramostim, Control Arm - Transplant-Related Hematologic Malignancy | Phase 2 | Recruiting | Northside Hospital, Inc. | 38 | 2020-05-18 | 2026-10-14 |
| Immunotherapy With Tacrolimus Resistant EBV CTL for Lymphoproliferative Disease After Solid Organ Transplant Autologous EBV-CTL transduced with vector SFG-CNA12, Autologous EBV-CTL transduced with control vector SFG-CNA8, Leucapheresis - Post-transplant Lymphoproliferative Disease, Transplant-Related Hematologic Malignancy | Early Phase 1 | Completed | University College, London | 4 | 2019-05-31 | 2026-08-07 |
| Peripheral Blood Stem Cell Transplantation From Family Haploidentical Donors in Patients With Myelodysplastic Syndrome and Acute Leukemia Under Primary Prophylaxis With Posaconazole Conditioning treatment "Thiotepa-Treosulfan-Fludarabine", PBSC graft, GvHD prophylaxis - Transplant-Related Hematologic Malignancy, Leukemia, Acute | Phase 2 | Completed | Ciceri Fabio | 10 | 2018-06-18 | 2022-07-19 |
| Treosulfan-TMI Conditioning and Rapamycin GvHD Prophylaxis Before Allo-HSCT Conditioning treatment "Treosulfan-TMI", SCT, GvHD prophylaxis - Irradiated Bone Marrow, Transplant-Related Hematologic Malignancy | Phase 1 | Terminated | IRCCS San Raffaele | 9 | 2014-02-12 | 2020-10-19 |
| Transplantation of Hematopoietic Progenitors From Haploidentical Donor With Selective in Vitro Depletion Allo-reactive Lymphocytes in Patient With High Risk Hematological Malignancies Allo-depleted lymphocyte infusion, Haploidentical transplantation of hematopoietic progenitors - Transplant-Related Hematologic Malignancy | Phase 1 | Withdrawn | Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud | 2013-01-01 | 2018-07-06 | |
| Phase II Trial in Elderly Patients With AML or MDS in Complete Remission Not Eligible for Allogenic Transplant Fludarabine, ARA-C, Treosulfan - Acute Myeloid Leukemia, Myelodysplastic Syndromes | Phase 2 | Completed | Ciceri Fabio | 15 | 2009-02-10 | 2023-11-18 |
Graft vs Host Disease (2) · Leukemia (2) · Leukemia, Myeloid, Acute (2) · Myelodysplastic Syndromes (2) · Multiple Myeloma (1) · Mycoses (1)
Hematologic Diseases (4) · Hemic and Lymphatic Diseases (4) · Neoplasms (4) · Neoplasms by Histologic Type (4) · Bone Marrow Diseases (2) · Immune System Diseases (2) · Leukemia (2) · Leukemia, Myeloid (2) · Bacterial Infections and Mycoses (1) · Blood Protein Disorders (1) · Cardiovascular Diseases (1) · Hemorrhagic Disorders (1) · Hemostatic Disorders (1) · Immunoproliferative Disorders (1) · Infections (1)
Cytarabine (1) · Granulocyte Colony-Stimulating Factor (1) · Granulocyte-Macrophage Colony-Stimulating Factor (1) · Leukapheresis (1) · Peripheral Blood Stem Cell Transplantation (1) · fludarabine (1) · revumenib (1) · sargramostim (1) · treosulfan (1)
Ciceri Fabio (2) · Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud (1) · Center for International Blood and Marrow Transplant Research (1) · IRCCS San Raffaele (1) · Northside Hospital, Inc. (1) · University College, London (1)
Italy (3) · Spain (1) · United Kingdom (1) · United States (1)
Antonio Torres, MD, PhD (1) · Fabio Ciceri, MD (1) · Melhem Solh, MD (1) · Prof. Persis Amrolia (1) · Steven Devine, M.D (1)
2008 (1), 2017 (1)