3 recruiting, 2 active not recruiting. 2 Phase 1, 2 Phase 2, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Active not recruiting 1, Recruiting 1 |
| Phase 2 | 2 | Active not recruiting 1, Recruiting 1 |
| Not applicable | 1 | Recruiting 1 |
| Phase 3 | 1 | Active not recruiting 1 |
Follow Stage IV Sinonasal Cancer AJCC v8: new trials by email Literature Review of Stage IV Sinonasal Cancer AJCC v8 trials Research Report on Stage IV Sinonasal Cancer AJCC v8
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation Audiometric Test, Interview - Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Cutaneous Squamous Cell Carcinoma of the Head and Neck | Not applicable | Recruiting | Emory University | 118 | 2025-08-25 | 2026-07-16 |
| TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography - Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Metastatic Head and Neck Squamous Cell Carcinoma | Phase 1 | Recruiting | Emory University | 40 | 2025-05-08 | 2026-03-04 |
| Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial Biospecimen Collection, Computed Tomography, Lovastatin - Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Human Papillomavirus-Related Neck Squamous Cell Carcinoma of Unknown Primary | Phase 2 | Recruiting | Emory University | 28 | 2024-12-09 | 2026-02-11 |
| Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers Atezolizumab, Bevacizumab, Biospecimen Collection - Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Metastatic Head and Neck Squamous Cell Carcinoma | Phase 2 / Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 430 | 2023-03-13 | 2026-10-01 |
| Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck Cancer Biospecimen Collection, Computed Tomography, Elimusertib - Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 7 | 2022-07-06 | 2026-08-21 |
Carcinoma (5) · Hypopharyngeal Neoplasms (5) · Laryngeal Neoplasms (5) · Mouth Neoplasms (5) · Oropharyngeal Neoplasms (5) · Squamous Cell Carcinoma of Head and Neck (5) · Nasopharyngeal Carcinoma (4) · Lymphoid Interstitial Pneumonia (1) · Recurrence (1) · Salivary Gland Neoplasms (1)
Carcinoma, Squamous Cell (5) · Head and Neck Neoplasms (5) · Laryngeal Diseases (5) · Mouth Diseases (5) · Neoplasms (5) · Neoplasms by Histologic Type (5) · Neoplasms by Site (5) · Neoplasms, Glandular and Epithelial (5) · Otorhinolaryngologic Diseases (5) · Otorhinolaryngologic Neoplasms (5) · Pharyngeal Diseases (5) · Pharyngeal Neoplasms (5) · Respiratory Tract Diseases (5) · Respiratory Tract Neoplasms (5) · Stomatognathic Diseases (5)
Magnetic Resonance Spectroscopy (4) · Specimen Handling (4) · pembrolizumab (3) · (225)Ac-DOTA-c(RGDyK) (1) · 1,2-diaminocyclohexaneplatinum II citrate (1) · BAY 1895344 (1) · Bevacizumab (1) · Carboplatin (1) · Cetuximab (1) · Cisplatin (1) · Disulfides (1) · Docetaxel (1) · Hearing (1) · Immunoglobulin G (1) · Interviews as Topic (1)
Emory University (3) · National Cancer Institute (NCI) (2)
United States (5)
Aarti Bhatia (1) · Dong M. Shin, MD, FACP, FAAAS (1) · Nicole C Schmitt, D, FACS (1) · Nicole C Schmitt, MD, FACS (1) · Yvonne M Mowery (1)
P30CA138292 (3), K24DC022077 (1), R01CA262123 (1), U10CA180820 (1), UM1CA186690 (1)