22 completed, 12 recruiting, 5 not yet recruiting, 3 terminated. 29 Phase 1, 6 Not applicable, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 29 | Completed 20, Not yet recruiting 3, Recruiting 3, Terminated 3 |
| Not applicable | 6 | Recruiting 5, Completed 1 |
| Phase 2 | 6 | Recruiting 3, Not yet recruiting 2, Completed 1 |
Follow Solid Cancers: new trials by email Literature Review of Solid Cancers trials Research Report on Solid Cancers
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase II Trial of Tunlametinib in Patients With NRAS Mutant Non-melanoma Refractory Solid Tumors Tunlametinib - Solid Cancers | Phase 2 | Recruiting | Tianjin Medical University Second Hospital | 15 | 2027-08-31 | 2025-09-12 |
| Monitoring of Immunological Mechanisms and Biomarkers Underlying Efficacy of Immunotherapy in Patients With Early Stage Cancer Patients treated with immune checkpoint blockade in neo-adjuvant setting and possibly in adjuvant setting (if applicable) - Solid Cancers | Not applicable | Recruiting | Institut Claudius Regaud | 600 | 2026-08-06 | 2026-08-19 |
| JY016 Injection in Patients With Advanced Solid Tumors Expressing EGFR JY016 - Solid Cancers | Phase 1 / Phase 2 | Not yet recruiting | Biotech Pharmaceutical Co., Ltd. | 228 | 2026-04-30 | 2026-04-06 |
| Predicting Reactions and Effects of Drugs Immunotherapy and Complications Through Oncosafety (PREDICTO Clinical Study) Bloodsampling, Pharyngeal swab sampling, Cuteanous swab sampling - Solid Tumor Malignancies, Solid Cancers | Not applicable | Recruiting | Assistance Publique Hopitaux De Marseille | 160 | 2026-03-23 | 2026-10-28 |
| An Antibody-armored Dendritic Cell in Patients With Solid Tumors Armored Dendritic Cell Injection - Solid Cancers, Adjuvant Therapy | Phase 1 | Recruiting | Shanghai Cell Therapy Group Co.,Ltd | 8 | 2026-02-05 | 2026-03-18 |
| The Effect of Using Weighted Blanket on Anxiety, Stress, Depression and Comfort Level Among Patients With Cancer Undergoing Intravenous Anticancer Therapy and Its Feasibility of Use by Nurses Compared to Routine Care Weighted Blanket, Regular Hospital Blanket - Solid Cancers, Anxiety Depression | Not applicable | Recruiting | Sultan Qaboos Comprehensive Cancer Center | 152 | 2025-12-25 | 2026-06-17 |
| An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors TCC1727 tablet 90mg, TCC1727 tablet 120mg, TCC1727 tablet 160mg - Solid Cancers, NSCLC (Advanced Non-small Cell Lung Cancer) | Phase 1 / Phase 2 | Recruiting | Beijing Tide Pharmaceutical Co., Ltd | 266 | 2025-12-03 | 2026-01-28 |
| xDRIVE for Florida-based Cancer Patients xDRIVE Tumor Profiling - Cancer, Neoplams | Not applicable | Recruiting | First Ascent Biomedical Inc. | 210 | 2025-11-01 | 2026-05-19 |
| A Study to Evaluate the Safety and Tolerability of EP0089 EP0089-101 - Solid Cancers, Solid Tumours | Phase 1 / Phase 2 | Not yet recruiting | Ellipses Pharma | 190 | 2025-09-01 | 2025-06-22 |
| Real-life Performance Evaluation of the LiFlow X-ray Platform Radiologist interpretation - Solid Cancers | Not yet recruiting | University Hospital, Angers | 400 | 2025-09-01 | 2025-05-31 | |
| Spatially Fractionated Radiotherapy Combined With Immunotherapy for Advanced Solid Tumors lattice radiation therapy - Solid Cancers, Radiotherapy | Phase 2 | Recruiting | Tianjin Medical University Cancer Institute and Hospital | 30 | 2025-07-01 | 2026-04-29 |
| Application of the sG8 Scale in Real-World Geriatric Oncology Patients Geriatric Screening using the sG8 scale - Solid Cancers, Geriatric Assessment | Not yet recruiting | Sichuan Cancer Hospital and Research Institute | 346 | 2025-05-16 | 2025-04-23 | |
| Clonal Hematopoiesis Chemotherapy and Radiation Effects Study Samples - Lung Cancer (Diagnosis), Osteochondroma | Recruiting | Dana-Farber Cancer Institute | 5000 | 2025-04-04 | 2026-06-30 | |
| Serum IGF-1 and IGF-1Ec in Malignancy Assessment Cancer, Solid Tumor Malignancies | Active not recruiting | Çanakkale Onsekiz Mart University | 100 | 2025-04-01 | 2025-09-03 | |
| A Phase I Study of LXP1788 Injection with Advanced Solid Tumors. LXP1788 is administered intravenously via Port-A - Solid Tumor Malignancies, Cancer, Solid Cancers | Phase 1 | Recruiting | LaunXP Biomedical Co., Ltd. | 24 | 2024-12-31 | 2025-03-19 |
| A PARG Inhibitor DAT-2645 Monotherapy in Patients with Advanced/Metastatic Solid Tumors Harboring BRCA1/2 Loss of Function Alterations And/or Other Defects in the DDR Pathway DAT-2645 tablet - Solid Cancers, BRCA Mutation | Phase 1 | Not yet recruiting | Danatlas Pharmaceuticals Co., Ltd | 112 | 2024-11-01 | 2024-09-27 |
| A Dose-escalation, Dose-finding, and Expansion Study of XL495 in Participants With Locally Advanced or Metastatic Solid Tumors XL495, ADC cytotoxic agents - Solid Cancers, Solid Tumor Cancer | Phase 1 | Terminated | Exelixis | 9 | 2024-10-17 | 2025-06-25 |
| High- Fiber/ Low-fat Diet for Prevention of Recurrent Clostridioides Difficile Infection in Oncology Diet Intervention - Leukemia, Lymphocytic, Acute, Leukemia, Myeloid, Acute | Not applicable | Completed | University of Colorado, Denver | 8 | 2022-10-21 | 2026-09-10 |
| A Clinical Study of CEA-targeted CAR-T in the Treatment of CEA-positive Advanced Malignant Solid Tumors Intraperitoneal infusion of FAST CEA-targeted CAR-T, CEA CAR-T cells - Colorectal Cancer, Solid Cancers | Phase 1 | Completed | Weijia Fang, MD | 58 | 2022-05-25 | 2026-07-15 |
| 68Ga-PSMA-617 PET/CT for PSMA-expressing Tumor: a Pragmatic Study [68Ga]-PSMA-617 - Solid Cancers | Recruiting | Centre de recherche du Centre hospitalier universitaire de Sherbrooke | 1000 | 2022-01-21 | 2024-02-07 |
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Neoplasms (6) · Stomach Neoplasms (4) · Breast Neoplasms (2) · Carcinoma, Renal Cell (2) · Colorectal Neoplasms (2) · Endometrial Neoplasms (2) · Lung Neoplasms (2) · Lymphoma (2) · Pancreatic Neoplasms (2) · Adenocarcinoma Of Esophagus (1) · Anxiety Disorders (1) · Ataxia Telangiectasia (1) · Carcinoma, Basal Cell (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1)
Neoplasms (9) · Neoplasms by Histologic Type (8) · Neoplasms by Site (7) · Digestive System Diseases (5) · Digestive System Neoplasms (5) · Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Gastrointestinal Diseases (4) · Gastrointestinal Neoplasms (4) · Immune System Diseases (4) · Stomach Diseases (4) · Urogenital Diseases (4) · Urogenital Neoplasms (4) · Carcinoma (3) · Colonic Diseases (3)
Bevacizumab (7) · Paclitaxel (3) · 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one (2) · Carboplatin (2) · HhAntag691 (2) · Immune Checkpoint Inhibitors (2) · atezolizumab (2) · parsatuzumab (2) · vesencumab (2) · 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine (1) · 2-(3-(2-(1-isopropyl-3-methyl-1H-1,2-4-triazol-5-yl)-5,6-dihydrobenzo(f)imidazo(1,2-d)(1,4)oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanamide (1) · Capecitabine (1) · Cisplatin (1) · Docetaxel (1) · Fulvestrant (1)
Genentech, Inc. (18) · Hoffmann-La Roche (2) · Institut Claudius Regaud (2) · Assistance Publique Hopitaux De Marseille (1) · Beijing Tide Pharmaceutical Co., Ltd (1) · Biotech Pharmaceutical Co., Ltd. (1) · Centre de recherche du Centre hospitalier universitaire de Sherbrooke (1) · Dana-Farber Cancer Institute (1) · Danatlas Pharmaceuticals Co., Ltd (1) · Ellipses Pharma (1) · Exelixis (1) · First Ascent Biomedical Inc. (1) · LaunXP Biomedical Co., Ltd. (1) · Medical University of South Carolina (1) · Semafore Pharmaceuticals (1)
United States (18) · China (6) · France (5) · Spain (5) · Canada (2) · Belgium (1) · Netherlands (1) · Oman (1) · Taiwan (1) · Turkey (Türkiye) (1)
Rainer Brachmann, M.D. (2) · Catherine Lozupone (1) · Chia Portera, M.D., Ph.D. (1) · Christophe Aube (1) · Dawn Colburn, Pharm.D. (1) · Donald L Durden, MD, PhD (1) · Dr. Huda S Al Awaisi, PhD (1) · Haitao Wang, Ph.D (1) · Harald Weber, M.D. (1) · Ina Rhee, M.D. (1) · Iris Chan, M.D., Ph.D. (1) · Jennifer Low, M.D. (1) · Jerry Hsu, M.D. (1) · Lachelle D Weeks, MD, PhD (1)
PMID 22623056, PMID 22921184, PMID 25009010, PMID 27872130, PMID 28250200, PMID 34471960, PMID 35577503, PMID 38937298, PMID 39734708, PMID 41760800
2014 (2), 2009 (1), P30CA046934 (1), U01AI150589 (1)