8 completed. 8 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 8 |
| Phase 2 | 1 | Completed 1 |
Follow Soft Tissue Injuries: new trials by email Literature Review of Soft Tissue Injuries trials Research Report on Soft Tissue Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase III Trial to Evaluate the Efficacy and Safety in Patients With Ankle Sprains. Esflurbiprofen Topical System (EFTS), Placebo Patch - Ankle Sprains | Phase 3 | Completed | Teikoku Seiyaku Co., Ltd. | 69 | 2025-03-31 | 2025-11-26 |
| Phase III Trial to Assess the Safety and Efficacy of TK-254RX in Patients With Contusions Esflurbiprofen Topical System (EFTS) - Contusions | Phase 3 | Completed | Teikoku Seiyaku Co., Ltd. | 221 | 2025-02-20 | 2025-10-24 |
| Study of PK and Safety of the LicartTM Topical System in Pediatric and Adult Participants With Minor Soft Tissue Injury Licart™ (diclofenac epolamine) topical system - Soft Tissue Injuries | Phase 3 | Completed | IBSA Institut Biochimique SA | 151 | 2021-10-31 | 2026-09-30 |
| Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Applied Four Times Daily in Subjects With Acute Ankle Sprain Diclofenac Sodium, Placebo - Acute Ankle Sprain | Phase 3 | Completed | Novartis | 205 | 2011-01-01 | 2013-01-24 |
| Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Applied 4 Times Daily in Subjects With Acute Ankle Sprain Diclofenac sodium topical gel 1%, Placebo - Ankle Sprain | Phase 3 | Completed | Novartis | 206 | 2010-11-01 | 2012-10-04 |
| Evaluate the Efficacy and Safety of Diclofenac Diethylamine 2.32% Gel Applied Twice or Three Times Daily in Patients With Acute Ankle Sprain diclofenac diethylamine gel 2.32%, Placebo - Grade I/II Ankle Sprain | Phase 3 | Completed | Novartis | 242 | 2009-07-01 | 2012-04-20 |
| Diclofenac Patch for Treatment of Acute Pain Due to Mild to Moderate Soft Tissue Injuries (TAPED) Diclofenac Sodium, Matching Placebo Patch - Acute Pain, Soft Tissue Injury | Phase 3 | Completed | Cerimon Pharmaceuticals | 407 | 2009-04-01 | 2010-08-16 |
| Hyperbaric Oxygen in Lower Leg Trauma Hyperbaric Oxygen Treatment - Tibial Fracture, Soft Tissue Injury | Phase 2 / Phase 3 | Completed | Bayside Health | 120 | 2007-02-13 | 2023-09-05 |
Ankle Injuries (4) · Athletic Injuries (2) · Wounds, Nonpenetrating (2) · Acute Pain (1) · Contusions (1) · Crush Injuries (1) · Tibial Fractures (1)
Wounds and Injuries (8) · Leg Injuries (5) · Fractures, Bone (1) · Neurologic Manifestations (1) · Pain (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
Diclofenac (2) · Drug Delivery Systems (1) · Hyperbaric Oxygenation (1) · diclofenac hydroxyethylpyrrolidine (1)
Novartis (3) · Teikoku Seiyaku Co., Ltd. (2) · Bayside Health (1) · Cerimon Pharmaceuticals (1) · IBSA Institut Biochimique SA (1)
Germany (4) · United States (4) · Australia (1) · Austria (1) · Chile (1) · Czechia (1) · India (1) · Italy (1) · Portugal (1) · Sweden (1)
Kenichi Nishiyama (2) · Giuseppe Mautone, MD (1) · Ian L Millar, MBBS (1) · Owen Williamson (1) · Peter Cameron (1)