5 recruiting, 2 completed, 1 unknown. 4 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Recruiting 4 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Smell Loss: new trials by email Literature Review of Smell Loss trials Research Report on Smell Loss
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training Smell Training - Smell Loss, Chronic Rhinosinusitis (CRS) | Not applicable | Recruiting | The Cleveland Clinic | 52 | 2025-12-09 | 2026-07-02 |
| Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients. Dupilumab - Standard Dose - Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP), Smell Loss | Recruiting | Northwestern University | 30 | 2025-05-01 | 2026-07-16 | |
| Scents of Progress: Leveraging a Novel Device for Olfactory Training in Older Adults Sudoku Puzzles, ScentCare (Olfactory Training Device) - Olfactory Dysfunction, Smell Loss | Not applicable | Recruiting | Johns Hopkins University | 60 | 2025-04-15 | 2026-04-13 |
| Olfactory Biopsies olfactory testing, Odor stimulation, Olfactory biopsy - Alzheimer Disease, Smell Loss | Not applicable | Recruiting | Duke University | 125 | 2025-01-06 | 2026-06-12 |
| Olfactory Training on Smell Dysfunction Patients in HK Olfactory Training, Control - Olfaction Disorders, Smell Disorders | Not applicable | Recruiting | Pamela Youde Nethersole Eastern Hospital | 80 | 2022-07-01 | 2025-06-03 |
| Preparation and Characterization Intranasal Film Loaded With Steroid as a Local Treatment of Anosmia in Compare to Insulin Intranasal Film Prednisolone - Smell Loss | Phase 1 / Phase 2 | Completed | Deraya University | 200 | 2022-03-01 | 2023-06-01 |
| Intranasal Insulin for COVID-19-related Smell Loss Insulin - Anosmia, Smell Loss | Phase 3 | Completed | Universidad Panamericana | 27 | 2021-01-04 | 2022-07-18 |
| Clinical and Immunological Responses After SARS-CoV-2 Infection Causing COVID-19 COVID-19 antibody test - Covid19, SARS-CoV2 Infection | Unknown | Association "Naso Sano" Onlus | 100 | 2020-05-01 | 2023-04-14 |
Anosmia (8) · Olfaction Disorders (4) · COVID-19 (2) · Alzheimer Disease (1) · Nasal Polyps (1)
Nervous System Diseases (8) · Neurologic Manifestations (8) · Pathological Conditions, Signs and Symptoms (8) · Sensation Disorders (8) · Signs and Symptoms (8) · Olfaction Disorders (4) · Respiratory Tract Diseases (3) · Coronaviridae Infections (2) · Coronavirus Infections (2) · Infections (2) · Lung Diseases (2) · Nidovirales Infections (2) · Pneumonia (2) · Pneumonia, Viral (2) · RNA Virus Infections (2)
Olfactory Training (2) · COVID-19 Serological Testing (1) · Insulin (1) · Prednisolone (1) · dupilumab (1)
Association "Naso Sano" Onlus (1) · Deraya University (1) · Duke University (1) · Johns Hopkins University (1) · Northwestern University (1) · Pamela Youde Nethersole Eastern Hospital (1) · The Cleveland Clinic (1) · Universidad Panamericana (1)
United States (4) · Egypt (1) · Hong Kong (1) · Italy (1) · Mexico (1)
Bradley Goldstein, MD, PhD (1) · Kai Chuen Fergus Wong, FRCSEd(ORL) (1) · Mohamad Chaaban, MD (1) · Nicholas Rowan, M.D. (1) · Puya Dehgani-Mobaraki, MD (1)
PMID 29557250, PMID 32835303, PMID 32991844, PMID 33497610, PMID 33862126, PMID 33937733
R01DC021422 (1)