1 completed, 1 recruiting, 1 terminated. 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Terminated 1 |
Follow SMARCA4 Gene Mutation: new trials by email Literature Review of SMARCA4 Gene Mutation trials Research Report on SMARCA4 Gene Mutation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation PRT3789, pembrolizumab - Advanced Solid Tumor, Esophageal Cancer | Phase 2 | Terminated | Prelude Therapeutics Incorporated | 6 | 2025-06-03 | 2026-02-02 |
| PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 Mutation PRT3789, Docetaxel - Advanced Solid Tumor, Metastatic Solid Tumor | Phase 1 | Completed | Prelude Therapeutics Incorporated | 135 | 2023-05-02 | 2025-10-16 |
| Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight 16P11.2 Deletion Syndrome, 16p11.2 Duplications | Recruiting | Simons Searchlight | 100000 | 2010-10-01 | 2026-07-23 |
Neoplasm Metastasis (2) · 15q24 Microdeletion (1) · 16p11.2 Deletion Syndrome (1) · Chromosome 15q13.3 Microdeletion Syndrome (1) · Chromosome 17q21.31 Deletion Syndrome (1) · Chromosome 1q21.1 Deletion Syndrome, 1.35-Mb (1) · Chromosome 1q21.1 Duplication Syndrome (1) · Chromosome 2q37 deletion syndrome (1) · Cornea Plana 1 (1) · Cri-du-Chat Syndrome (1) · Epileptic Encephalopathy, Early Infantile, 4 (1) · Esophageal Neoplasms (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Rhabdoid Tumor Predisposition Syndrome 2 (1)
Neoplasms (2) · Neoplastic Processes (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Abnormalities, Multiple (1) · Chromosome Disorders (1) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Esophageal Diseases (1) · Gastrointestinal Diseases (1) · Gastrointestinal Neoplasms (1) · Genetic Diseases, Inborn (1) · Head and Neck Neoplasms (1)
Docetaxel (1) · pembrolizumab (1)
Prelude Therapeutics Incorporated (2) · Simons Searchlight (1)
United States (3) · Spain (2) · France (1) · Netherlands (1) · Singapore (1)
Cora Taylor, PhD (1) · Wendy Chung, MD PhD (1)