9 withdrawn. 9 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Withdrawn 9 |
| Phase 2 | 3 | Withdrawn 3 |
Follow Sickle Cell Disease: new trials by email Literature Review of Sickle Cell Disease trials Research Report on Sickle Cell Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| US Phase I Study of ECT-001-CB in Patients With Sickle-Cell Disease ECT-001-CB (UM171-Expanded Cord Blood Transplant) - Sickle Cell Disease, Umbilical Cord Blood | Phase 1 | Withdrawn | ExCellThera inc. | 2021-07-13 | 2022-07-05 | |
| Deferoxamine for Sickle Cell Chronic Leg Ulcer Treatment Deferoxamine Product, Placebo - Chronic Cutaneous Ulcer, Sickle Cell Disease | Phase 1 / Phase 2 | Withdrawn | TauTona Group | 2020-07-21 | 2021-12-02 | |
| A Phase Ib Study of NVX-508 in Sickle Cell Disease NVX-508 - Sickle Cell Disease | Phase 1 | Withdrawn | Amma Owusu-Ansah, MD | 2018-07-01 | 2018-07-16 | |
| Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease Hematopoietic stem cell transplantation - Sickle Cell Disease | Phase 1 | Withdrawn | City of Hope Medical Center | 2018-02-02 | 2026-10-26 | |
| Mesenchymal Stromal Cells for Haplo Hematopoietic Cell Transplantation for Sickle Cell Disease Autologous MSCs - Sickle Cell Disease | Phase 1 | Withdrawn | Emory University | 2017-12-21 | 2018-11-07 | |
| Macrolide Therapy to Improve Forced Expiratory Volume in 1 Second in Adults With Sickle Cell Disease Azithromycin, Placebo - Sickle Cell Disease | Phase 1 / Phase 2 | Withdrawn | Vanderbilt University | 2016-09-01 | 2018-10-02 | |
| A Study of Oral L-citrulline in Sickle Cell Disease Oral L-citrulline - Sickle Cell Disease | Phase 1 | Withdrawn | University of Mississippi Medical Center | 2015-12-01 | 2018-06-21 | |
| A Pilot Study of Azithromycin Prophylaxis for Acute Chest Syndrome in Sickle Cell Disease Azithromycin - Sickle Cell Disease, Acute Chest Syndrome | Phase 1 | Withdrawn | University of Mississippi Medical Center | 2015-09-01 | 2018-06-21 | |
| Phase 1 Study of Zoledronic Acid in Sickle Cell Disease Placebo, Zoledronic Acid - Sickle Cell Disease | Phase 1 / Phase 2 | Withdrawn | Virginia Commonwealth University | 2007-06-01 | 2011-11-11 |
Anemia, Sickle Cell (9) · Acute Chest Syndrome (1)
Anemia (9) · Anemia, Hemolytic (9) · Anemia, Hemolytic, Congenital (9) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (9) · Genetic Diseases, Inborn (9) · Hematologic Diseases (9) · Hemic and Lymphatic Diseases (9) · Hemoglobinopathies (9) · Lung Diseases (1) · Respiration Disorders (1) · Respiratory Tract Diseases (1)
Azithromycin (2) · Citrulline (1) · Hematopoietic Stem Cell Transplantation (1) · Zoledronic Acid (1)
University of Mississippi Medical Center (2) · Amma Owusu-Ansah, MD (1) · City of Hope Medical Center (1) · Emory University (1) · ExCellThera inc. (1) · TauTona Group (1) · Vanderbilt University (1) · Virginia Commonwealth University (1)
United States (6)
Amma T Owusu-Ansah, MD (1) · Anna B. Pawlowska, MD (1) · Elizabeth Stenger, MD (1) · John D Roberts, M.D. (1) · Lakshmanan Krishnamurti, MD (1) · Michael R. DeBaun, M.D., M.P.H. (1)
K23HL133446 (1)