3 completed, 1 active not recruiting, 1 not yet recruiting, 1 withdrawn. 4 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 2, Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 4 | Completed 3, Active not recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase I Clinical Trial of ThINKK Adoptive Immunotherapy After Allogeneic Hematopoietic Transplantation in Children With Leukemia or Neuroblastoma Therapeutic Inducers of Natural Killer Killing (ThINKK) - Leukaemia (Acute Lymphoblastic), Leukaemia (Acute Myeloid) | Phase 1 | Not yet recruiting | Michel Duval | 12 | 2026-05-01 | 2026-04-08 |
| US Study of ECT-001-CB in Pediatric and Young Adult Patients With High-Risk Myeloid Malignancies ECT-001-CB (UM171-Expanded Cord Blood Transplant) - High Risk Myeloid Malignancies, Cord Blood Transplant | Phase 1 / Phase 2 | Completed | ExCellThera inc. | 13 | 2021-12-01 | 2026-03-24 |
| US Phase I Study of ECT-001-CB in Patients With Sickle-Cell Disease ECT-001-CB (UM171-Expanded Cord Blood Transplant) - Sickle Cell Disease, Umbilical Cord Blood | Phase 1 | Withdrawn | ExCellThera inc. | 2021-07-13 | 2022-07-05 | |
| US Study of UM171-Expanded CB in Patients With High Risk Leukemia/Myelodysplasia ECT-001-CB (UM171-Expanded Cord Blood Transplant) - High Risk Hematological Malignancy, Cord Blood Transplant | Phase 2 | Completed | ExCellThera inc. | 30 | 2020-11-13 | 2026-03-23 |
| UM171 Expanded Cord Blood In Patients With High-Risk Acute Leukemia/Myelodysplasia Transplant with an expanded ECT-001 cord blood - High Risk Hematologic Malignancy, Cord Blood Transplant | Phase 2 | Active not recruiting | Ciusss de L'Est de l'Île de Montréal | 30 | 2019-04-01 | 2025-10-27 |
| ECT-001 (UM171) Expanded Cord Blood Transplant to Treat High-risk Multiple Myeloma ECT-001 (UM171) expanded cord blood - Multiple Myeloma | Phase 1 / Phase 2 | Completed | Ciusss de L'Est de l'Île de Montréal | 19 | 2018-03-07 | 2026-03-18 |
Anemia, Sickle Cell (1) · Leukemia (1) · Leukemia, Myeloid, Acute (1) · Multiple Myeloma (1) · Neoplasm Metastasis (1) · Neuroblastoma (1) · Paroxysmal nonkinesigenic dyskinesia (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1)
Cyclophosphamide (1) · Thiotepa (1) · Transplantation (1) · Transplantation Conditioning (1)
Canada (3) · United States (3) · Netherlands (1)
Jean Roy, MD (1) · Michel Duval, MD (1) · Sabine Herblot, PhD (1) · Sandra Cohen, MD (1)