3 completed, 1 recruiting, 1 unknown. 1 Early Phase 1, 1 Not applicable, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 1 | Completed 1 |
| Not applicable | 1 | Completed 1 |
| Phase 3 | 1 | Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Septo-Optic Dysplasia: new trials by email Literature Review of Septo-Optic Dysplasia trials Research Report on Septo-Optic Dysplasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756) Setmelanotide, Placebo - Hypothalamic Obesity, Multiple Pituitary Hormone Deficiency Genetic Form | Phase 3 | Recruiting | Rhythm Pharmaceuticals, Inc. | 39 | 2025-09-23 | 2026-02-12 |
| Sleep Profile of Patients With Septo-optic Dysplasia Actigraphy, blood and salivary sample, and sleep evaluation - Septo-Optic Dysplasia, Agenesis of Corpus Callosum | Unknown | IRCCS National Neurological Institute "C. Mondino" Foundation | 45 | 2023-12-20 | 2024-02-15 | |
| Screening of Septo-optic Dysplasia During a Fetal Examination at 16-20 Weeks of Gestation Displaying optic chiasm for screening septooptic dysplasia - 2D Ultrasound, Cavum Septum Pellucidum | Not applicable | Completed | Gaziosmanpasa Research and Education Hospital | 52 | 2020-09-21 | 2023-02-08 |
| Biological Clock Dysfunction in Optic Nerve Hypoplasia Melatonin, Placebo Comparator - Biological Clock Dysfunction, Optic Nerve Hypoplasia | Early Phase 1 | Completed | Yale University | 100 | 2008-10-01 | 2020-09-25 |
| Endocrine Dysfunction and Growth Hormone Deficiency in Children With Optic Nerve Hypoplasia Nutropin AQ - Growth Hormone Deficiency, Septo-Optic Dysplasia | Phase 4 | Completed | Children's Hospital Los Angeles | 20 | 2004-12-01 | 2015-04-01 |
Optic Nerve Hypoplasia (3) · Agenesis of Corpus Callosum (1) · Blindness (1) · Dwarfism, Pituitary (1) · Hypopituitarism (1) · Sexual Infantilism (1) · Vision Disorders (1)
Congenital Abnormalities (5) · Congenital Cranial Dysinnervation Disorders (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Cranial Nerve Diseases (5) · Eye Diseases (5) · Nervous System Diseases (5) · Nervous System Malformations (5) · Ocular Motility Disorders (5) · Oculomotor Nerve Diseases (5) · Agenesis of Corpus Callosum (4) · Eye Diseases, Hereditary (3) · Genetic Diseases, Inborn (3) · Optic Nerve Diseases (3) · Endocrine System Diseases (2) · Optic Nerve Hypoplasia (2)
Actigraphy (1) · Blood Specimen Collection (1) · Growth Hormone (1) · Melatonin (1) · setmelanotide (1)
Children's Hospital Los Angeles (1) · Gaziosmanpasa Research and Education Hospital (1) · IRCCS National Neurological Institute "C. Mondino" Foundation (1) · Rhythm Pharmaceuticals, Inc. (1) · Yale University (1)
United States (3) · Italy (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Casandra Fink (1) · David Meeker, MD (1) · Mark Borchert, MD (1) · Mitchell Geffner, MD (1)