2 recruiting, 1 completed, 1 terminated, 1 unknown. 5 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Recruiting 2, Completed 1, Terminated 1, Unknown 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Schizophrenia, Treatment-Resistant: new trials by email Literature Review of Schizophrenia, Treatment-Resistant trials Research Report on Schizophrenia, Treatment-Resistant
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant Schizophrenia Evenamide 15 mg bid, Placebo - Treatment-resistant Schizophrenia | Phase 3 | Recruiting | Newron Pharmaceuticals SPA | 400 | 2026-01-23 | 2026-09-10 |
| SMART Design to Compare Antipsychotic Treatments in Treatment-Resistant Schizophrenia Clozapine, MECT, DBS - Treatment-resistant Schizophrenia | Phase 3 | Unknown | Shanghai Mental Health Center | 162 | 2020-12-01 | 2020-08-27 |
| Efficacy of Lu AF35700 in Patients With Early-in-disease or Late-in-disease Treatment-resistant Schizophrenia Lu AF35700, Risperidone, Olanzapine - Treatment-resistant Schizophrenia | Phase 3 | Terminated | H. Lundbeck A/S | 119 | 2017-07-20 | 2020-01-21 |
| An Adaptive Phase II/III, Two-Part, Double-Blind, Randomized, Placebo-controlled, Dose-Finding, Multi-center Study of the Safety and Efficacy of NaBen®, as an Add-on Therapy With Clozapine, for Residual Symptoms of Refractory Schizophrenia in Adults NaBen®, Placebo - Refractory Schizophrenia | Phase 2 / Phase 3 | Recruiting | SyneuRx International (Taiwan) Corp | 287 | 2017-03-29 | 2021-09-13 |
| A Pilot Double-blind Sham-controlled Trial of Repetitive Transcranial Magnetic Stimulation for Patients With Refractory Schizophrenia Treated With Clozapine Active rTMS x sham (placebo) rTMS, sham rTMS, (1Hz) rTMS applied over the left temporoparietal cortex - Schizophrenia, Auditory Hallucinations | Phase 3 | Completed | Hospital de Clinicas de Porto Alegre | 20 | 2008-05-01 | 2010-08-12 |
Schizophrenia (3) · Hallucinations (1)
Mental Disorders (5) · Schizophrenia Spectrum and Other Psychotic Disorders (5) · Schizophrenia (2) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Neurologic Manifestations (1) · Pathological Conditions, Signs and Symptoms (1) · Perceptual Disorders (1) · Signs and Symptoms (1)
BID protein, human (1) · Clozapine (1) · Lu AF35700 (1) · Olanzapine (1) · Risperidone (1) · Transcranial Magnetic Stimulation (1) · salicylhydroxamic acid (1)
H. Lundbeck A/S (1) · Hospital de Clinicas de Porto Alegre (1) · Newron Pharmaceuticals SPA (1) · Shanghai Mental Health Center (1) · SyneuRx International (Taiwan) Corp (1)
United States (3) · Argentina (1) · Brazil (1) · Bulgaria (1) · China (1) · India (1) · Japan (1) · Malaysia (1) · Russia (1) · United Kingdom (1)
Danilo Jesus, Psychiatrist (1) · Dengtang Liu, MD (1) · Paulo B Abreu, phd (1) · Ravi Anand, MD (1)