4 active not recruiting, 2 completed, 1 suspended, 1 terminated. 9 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Active not recruiting 4, Completed 2, Suspended 1, Terminated 1, Unknown 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
Follow Rodent Diseases: new trials by email Literature Review of Rodent Diseases trials Research Report on Rodent Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 3 Maternal Safety & Immunogenicity Trial of MVA-BN® in DRC MVA-BN standard regimen, MVA-BN standard regimen (Administered as PEP) - Neonate, Maternal Transmission | Phase 3 | Active not recruiting | Jean-Pierre Van geertruyden | 359 | 2025-06-23 | 2026-01-30 |
| Phase 3 Infant Safety & Immunogenicity Trial of MVA-BN® in DRC MVA-BN standard regimen, MVA-BN half-dose regimen - Mpox (Monkeypox), Vaccination | Phase 3 | Active not recruiting | Jean-Pierre Van geertruyden | 344 | 2025-05-29 | 2026-04-29 |
| Efficacy/Effectiveness, Safety, and Immunogenicity of LC16m8 Mpox Vaccine in Colombia LC16m8 - Monkeypox | Phase 3 | Active not recruiting | Universidad Nacional de Colombia | 8686 | 2023-12-16 | 2025-09-04 |
| Tecovirimat in Non-hospitalized Patients With Monkeypox Tecovirimat, Placebo - Monkeypox | Phase 3 | Suspended | Marina Klein | 120 | 2023-08-14 | 2026-03-04 |
| Assessment of the Efficacy and Safety of Tecovirimat in Patients With Monkeypox Virus Disease Tecovirimat, Placebo - Monkeypox, Mpox | Phase 3 | Active not recruiting | ANRS, Emerging Infectious Diseases | 480 | 2023-03-03 | 2026-05-26 |
| Study of Tecovirimat for Human Mpox Virus Tecovirimat Oral Capsule, Placebo for Tecovirimat, Tecovirimat Oral Capsule (Open Label) - MPOX | Phase 3 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 719 | 2022-09-08 | 2026-06-23 |
| Study on Immunogenicity, Reactogenicity and Safety of the VACΔ6 Vaccine in Volunteers Aged 18-60 Years VAC∆6 vaccine (10⁷ PFU), VAC∆6 vaccine (10⁶ PFU), Live Smallpox Vaccine - Smallpox, Monkeypox | Phase 2 / Phase 3 | Completed | Federal Budgetary Research Institution State Research Center of Virology and Biotechnology "Vector" | 334 | 2021-10-01 | 2023-05-06 |
| FOS Immunohistochemical Staining of Colorectal Cancer and Its Adjacent Tissues Immunohistochemical staining with anti-FOS - Colorectal Cancer, Monkey Pox | Phase 2 / Phase 3 | Unknown | xiaoliang Huang | 120 | 2020-12-01 | 2023-01-26 |
| JYNNEOS Smallpox Vaccine in Adult Healthcare Personnel at Risk for Mpox in the Democratic Republic of the Congo JYNNEOS (Liquid Formulation), JYNNEOS (Lyophilized Formulation) - Monkeypox Virus Infection | Phase 3 | Completed | Centers for Disease Control and Prevention | 1600 | 2017-02-23 | 2026-04-23 |
Mpox, Monkeypox (9) · Smallpox (3) · Colorectal Neoplasms (1) · Cowpox (1) · Vaccinia (1)
Animal Diseases (9) · DNA Virus Infections (9) · Infections (9) · Poxviridae Infections (9) · Primate Diseases (9) · Virus Diseases (9) · Colonic Diseases (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Gastrointestinal Diseases (1) · Gastrointestinal Neoplasms (1) · Intestinal Diseases (1) · Intestinal Neoplasms (1) · Neoplasms (1)
tecovirimat (3) · smallpox and monkeypox vaccine modified vaccinia ankara-bavarian nordic (1) · smallpox vaccine LC16m8 (1)
Jean-Pierre Van geertruyden (2) · ANRS, Emerging Infectious Diseases (1) · Centers for Disease Control and Prevention (1) · Federal Budgetary Research Institution State Research Center of Virology and Biotechnology "Vector" (1) · Marina Klein (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Universidad Nacional de Colombia (1) · xiaoliang Huang (1)
Democratic Republic of the Congo (3) · Argentina (2) · Brazil (2) · Canada (1) · China (1) · Colombia (1) · Mexico (1) · Peru (1) · Russia (1) · Switzerland (1) · Thailand (1) · United States (1)
Faisal Minhaj, Pharm.D., MPH, DABAT (1) · Irina V Krasil'nikova, PhD (1) · Kinkodi Didine Kaba, MD, PhD (1) · Timothy Wilkin, MD, MPH (1) · Vladimir I. Kuzubov, PhD (1) · Yazdan Yazdapanah, Pr. (1)
PMID 30445121, PMID 36263798, PMID 40245474, PMID 41740032, PMID 41819114, PMID 41819117, PMID 42372625, PMID 42521300