1101 completed, 244 unknown, 136 terminated, 56 withdrawn. 1639 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 1639 | Completed 1101, Unknown 244, Terminated 136, Withdrawn 56, Recruiting 43, Active not recruiting 28, Not yet recruiting 22, Suspended 5, Enrolling by invitation 4 |
Follow RNA Virus Infections: new trials by email Literature Review of RNA Virus Infections trials Research Report on RNA Virus Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combating Related Epidemics in HCV Cepheid GeneXpert HCV Test, Abbott Determine HIV - 1/2 Ag/Ab, Abbott Determine HbsAg 2 - HIV - Human Immunodeficiency Virus, Hepatitis B Virus (HBV) | Phase 4 | Not yet recruiting | Duke University | 1280 | 2027-01-20 | 2026-10-15 |
| Reaching Persons With HIV Who Are Out of Care Through Expedited Access to Long-Acting Injectable Antiretroviral Therapy - The RELAI Study Field-based LA-CAB/RPV - HIV Infection | Phase 4 | Not yet recruiting | University of North Carolina, Chapel Hill | 40 | 2027-01-01 | 2026-10-26 |
| AI-Powered Hepatitis C Single-Encounter Test-and-Treat Epclusa (sofosbuvir and velpatasvir) - HEPATITIS C (HCV) | Phase 4 | Not yet recruiting | Patrick Grace | 35 | 2026-12-01 | 2026-08-28 |
| How Healthy Adults Respond to the Nasal Flu Vaccine FluMist (Live Attenuated Influenza Vaccine) - Mucosal Immune Response to Influenza Vaccination | Phase 4 | Not yet recruiting | University of Alabama at Birmingham | 20 | 2026-12-01 | 2026-10-13 |
| Preoperative Pneumococcal and Influenza Vaccination to Prevent Postoperative Pulmonary Infection in Patients Undergoing Lung Resection for Pulmonary Nodules or Lung Cancer 23-valent pneumococcal polysaccharide vaccine, Quadrivalent split-virion influenza vaccine - Pneumococcal Polysaccharide Vaccine, Influenza Vaccines | Phase 4 | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 1278 | 2026-11-01 | 2026-10-21 |
| Immunogenicity of Standard-Dose Versus High-Dose Influenza Vaccines in Older Adults in Singapore High-dose influenza vaccine, Standard-dose influenza vaccine - Influenza | Phase 4 | Not yet recruiting | Tan Tock Seng Hospital | 150 | 2026-11-01 | 2026-10-20 |
| SAFE (Self-Administration of Flumist to ImprovE Uptake: A Household-Based Cluster Randomized Trial) LAIV FLUMIST - Influenza (Healthy Volunteers) | Phase 4 | Not yet recruiting | McMaster University | 966 | 2026-10-15 | 2026-07-31 |
| A Study of Updated mRNA Seasonal Influenza Vaccines mRNA-1010, Licensed High-Dose Seasonal Influenza Vaccine - Seasonal Influenza | Phase 4 | Not yet recruiting | ModernaTX, Inc. | 200 | 2026-10-15 | 2026-10-20 |
| A Study to Evaluate the Immune Responses of Subunit Influenza Vaccine in Healthy Adults Group A, Group B - Influenza | Phase 4 | Active not recruiting | Ab&B Bio-tech Co., Ltd.JS | 138 | 2026-10-10 | 2026-10-16 |
| A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Formulations mRNA-1273, mRNA-1283 - SARS-CoV-2 | Phase 4 | Recruiting | ModernaTX, Inc. | 300 | 2026-10-09 | 2026-10-27 |
| Sleep Outcomes and Multidimensional Sleep Assessment - a Randomized Trial of Dolutegravir- vs Doravirine-based Antiretroviral Therapy in People Living With HIV Tenofovir disoproxil fumarate 300mg / Lamivudine 300mg / Doravirine 100mg, Tenofovir disoproxil fumarate 300mg / Lamivudine 300mg / Dolutegravir 50mg - HIV (Human Immunodeficiency Virus), Sleep | Phase 4 | Not yet recruiting | University of Witwatersrand, South Africa | 40 | 2026-10-05 | 2026-10-06 |
| Study of a Recombinant Spike COVID-19 Vaccine With Matrix-M in Older Adults and People at Increased Risk of Severe COVID-19 Omicron Subvariant-Based SARS-CoV-2 Recombinant Spike Vaccine Adjuvanted With Matrix-M - COVID-19 | Phase 4 | Recruiting | Sanofi | 660 | 2026-10-01 | 2026-10-15 |
| A Phase IV Clinical Trial of Influenza Vaccine (Split Virion), Inactivatedin (Anflu®) Pregnant Women (AnFLU-PREG) Anflu®, Vaxigrip® - Influenza | Phase 4 | Not yet recruiting | Sinovac Biotech Co., Ltd | 150 | 2026-10-01 | 2026-09-21 |
| Influenza Vaccine Immunogenicity in Repeatedly Vaccinated Older Adults Standard dose influenza vaccine, MF59 adjuvanted influenza vaccine, High dose influenza vaccine - Influenza Vaccination, Older Adults (65 Years and Older) | Phase 4 | Recruiting | Korea University Guro Hospital | 180 | 2026-09-21 | 2026-09-24 |
| BRAVO is a Phased Outbreak-response Study in the DRC Evaluating ERVEBO® Vaccination in ~20,000 Frontline Workers During the 2026 BDV Outbreak, Step A Assesses Real-world Effectiveness, Safety, and Impact on Severe Disease and Mortality, While Generating Evidence for Future BDV Vaccination Strategies ERVEBO Vaccination - Ebola, Bundibugyo Virus Disease (BVD) | Phase 4 | Recruiting | Epicentre | 20000 | 2026-09-19 | 2026-10-29 |
| Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV Vaginal estradiol tablets, Vaginal moisturizer - Menopausal Complaints, Vaginal Atrophy | Phase 4 | Not yet recruiting | Albert Einstein College of Medicine | 62 | 2026-09-01 | 2026-07-28 |
| The EMBRACE Study: Enflonsia Monoclonal in Babies - RSV Antibody Concentration Evaluation Clesrovimab - RSV Infection | Phase 4 | Not yet recruiting | Emory University | 24 | 2026-09-01 | 2026-09-17 |
| NOTRE: Optimizing Long-Acting Pre-Exposure Prophylaxis and Medications for Opioid Use Disorder Interventions in Carceral Settings Cabotegravir Injection, Cabotegravir Pill, Buprenorphine injection - HIV Infections, Opioid Use Disorder | Phase 4 | Not yet recruiting | Duke University | 450 | 2026-09-01 | 2026-08-26 |
| Effectiveness of An Influenza/COVID-19 Vaccine (mCombriax [mRNA-1083]) in Adults ≥ 65 Years mCombriax® (mRNA-1083), Efluelda® (TIV-HD) and Spikevax® (mRNA-1273) - COVID-19, Influenza | Phase 4 | Not yet recruiting | Tor Biering-Sørensen | 410000 | 2026-09-01 | 2026-08-27 |
| A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age BNT162b2 Vaccine, Tdap Vaccine - COVID-19 Vaccines | Phase 4 | Recruiting | BioNTech SE | 200 | 2026-07-23 | 2026-08-07 |
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HIV Infections (413) · Influenza, Human (345) · COVID-19 (242) · Acquired Immunodeficiency Syndrome (211) · Hepatitis C (184) · Hepatitis C, Chronic (144) · Poliomyelitis (59) · Coronavirus Infections (44) · Hepatitis A (32) · Hepatitis B (26) · Tuberculosis (26) · Measles (23) · Common Cold (21) · Infections (21) · Tetanus (21)
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Ribavirin (138) · Influenza Vaccines (136) · peginterferon alfa-2a (83) · Ritonavir (63) · Lamivudine (57) · Tenofovir (54) · efavirenz (48) · Emtricitabine (44) · Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (42) · Raltegravir Potassium (42) · Lopinavir (41) · Sofosbuvir (40) · lopinavir-ritonavir drug combination (35) · Nevirapine (30) · Atazanavir Sulfate (28)
GlaxoSmithKline (49) · Hoffmann-La Roche (44) · Sanofi Pasteur, a Sanofi Company (44) · National Institute of Allergy and Infectious Diseases (NIAID) (30) · Sinovac Biotech Co., Ltd (29) · Stanford University (23) · Kirby Institute (22) · Centers for Disease Control and Prevention (20) · Germans Trias i Pujol Hospital (20) · Jiangsu Province Centers for Disease Control and Prevention (19) · Merck Sharp & Dohme LLC (18) · University of California, San Francisco (17) · Duke University (16) · Emory University (15) · National Taiwan University Hospital (15)
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PMID 35244208, PMID 34473343, PMID 32710245, PMID 28963118, PMID 33502773, PMID 29706550, PMID 37591523, PMID 21366801, PMID 21378375, PMID 21592984, PMID 24508042, PMID 25297720, PMID 26069949, PMID 26190091, PMID 26867206, PMID 28545923, PMID 30552056, PMID 31984244, PMID 33487470, PMID 36658045, PMID 37096802, PMID 37489818, PMID 41276263, PMID 10218526, PMID 10219064, PMID 10342702, PMID 10439494, PMID 10471173, PMID 10628898, PMID 10934667, PMID 11172138, PMID 11188837, PMID 11225528, PMID 11228365, PMID 11505791, PMID 11672911, PMID 11744606, PMID 11813503, PMID 11855555, PMID 11915000, PMID 11984144, PMID 12375147, PMID 12443658, PMID 12594647, PMID 12798618, PMID 12809582, PMID 12915495, PMID 13998, PMID 14506371, PMID 14706961
U19AI057229 (15), 2005 (8), 2009 (8), 2015 (5), 2008 (4), 2014 (4), U01AI068632 (4), U01AI068636 (4), U19AI090019 (4), 2025 (3), UM1AI068636 (3), 2004 (2), 2016 (2), 2018 (2), 2019 (2)