200 completed, 88 unknown, 34 recruiting, 21 active not recruiting. 372 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 372 | Completed 200, Unknown 88, Recruiting 34, Active not recruiting 21, Terminated 14, Not yet recruiting 9, Withdrawn 5, Enrolling by invitation 1 |
Follow Prolapse: new trials by email Literature Review of Prolapse trials Research Report on Prolapse
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Improving Uroflowmetry Interpretability: Evaluating the Impact of Patient Reminder Systems Patient reminder system - Pelvic Organ Prolapse, Urinary Incontinence | Not applicable | Recruiting | Ohio State University | 162 | 2026-11-01 | 2026-09-24 |
| Safety and Performance of a Pelvic Floor Mesh Implant for Laparoscopic Sacrocolpopexy (ProGYNious) Surgical mesh for pelvic organ prolapse repair (ProGYNious) - Pelvic Organ Prolapse (POP), Synthetic Mesh | Not applicable | Recruiting | A.M.I. Agency for Medical Innovations GmbH | 100 | 2026-10-28 | 2026-10-30 |
| Perineal Protection Device for Reducing Perineal Trauma During Vaginal Delivery in First-time Mothers: a Multicenter Randomized Controlled Trial Perineal protection device, BabySlide, Standard manual perineal support - Pelvic Floor Dysfunction, Perineal Laceration | Not applicable | Not yet recruiting | Region Skane | 4226 | 2026-10-05 | 2026-10-07 |
| How Low Can You Go Standard insufflation, Low insufflation - Pelvic Organ Prolapse | Not applicable | Not yet recruiting | University of Calgary | 164 | 2026-09-01 | 2026-08-26 |
| Poly-L-Lactic Acid for Vulvovaginal Tissue Regeneration Poly-L-Lactic Acid (Sculptra) injection, Placebo injection (sterile water) - Pelvic Organ Prolapse (POP), Cystocele | Not applicable | Recruiting | Cassandra Kisby | 20 | 2026-08-20 | 2026-08-21 |
| Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy Deep Neuromuscular Blockade (NMB), Standard (moderate) neuromuscular blockade, Preoperative low-residue diet - Leiomyoma, Uterine, Benign Gynecological Disease | Not applicable | Recruiting | Fatih Sultan Mehmet Training and Research Hospital | 160 | 2026-07-01 | 2026-07-30 |
| Vaginal Vault Native Tissue Suspension Mackenrodt uterosacral double ligaments suspension - Pelvic Organ Prolapse | Not applicable | Recruiting | Assiut University | 10 | 2026-06-03 | 2026-06-04 |
| The Finnish Uterine Prolapse Surgery Trial (The Fin-UP Trial) Manchester procedure, Vaginal hysterectomy - Uterine Prolapse, Pelvic Organ Prolapse Vaginal Surgery | Not applicable | Recruiting | Tampere University Hospital | 426 | 2026-05-01 | 2026-05-11 |
| Evaluation of a Personalizable Pessary for Pelvic Organ Prolapse Novel Personalizable Pessary - Pelvic Organ Prolapse (POP) | Not applicable | Recruiting | University of Alberta | 43 | 2026-04-30 | 2026-06-04 |
| The RECOVER Study - Postpartum Recovery of Pelvic Floor Structures and the Impact of Early Rehabilitation Early individualized pelvic floor muscle training (PFMT) - Urinary Incontinence, Pelvic Organ Prolapse (POP) | Not applicable | Recruiting | Vastra Gotaland Region | 380 | 2026-04-07 | 2026-05-27 |
| Effect of Paracervical Block on Postoperative Pain After vNOTES Uterosacral Ligament Suspension Bupivacaine, Normal Saline - Pelvic Organ Prolapse (POP), Postoperative Pain | Not applicable | Recruiting | Erkan Gol | 58 | 2026-03-09 | 2026-03-11 |
| Safety and Performance of a Pelvic Floor Mesh Implant (LatGYNious) Laparoscopic lateral suspension with surgical mesh (LatGYNious) - Pelvic Organ Prolapse (POP), Genital Prolapse | Not applicable | Recruiting | A.M.I. Agency for Medical Innovations GmbH | 85 | 2025-11-01 | 2026-07-28 |
| SORE Study: Sitz Baths After Urogynecologic Reconstruction Sitz Bath - Pelvic Organ Prolapse, Postoperative Pain Management | Not applicable | Active not recruiting | Yale University | 112 | 2025-10-28 | 2026-09-08 |
| Pelvic Floor Muscle Training During Pregnancy PFMT, Standard care - Urinary Incontinence, Anal Incontinence | Not applicable | Recruiting | University of Southern Denmark | 804 | 2025-10-27 | 2026-10-08 |
| Are There Benefits of Using Energy-based Devices for Opportunistic Salpingo-oophorectomy During Vaginal Hysterectomy Compared to a Standard Cold Approach? LigaSure MaryLand, Standard salpingo-oophorectomy technique - Pelvic Organ Prolapse (POP) | Not applicable | Recruiting | Wolfson Medical Center | 70 | 2025-10-16 | 2026-01-30 |
| Enabling Self-Care for Pessary Users in Rural Setting Reia System pessary self-care management, Standard pessary office-based management - Pelvic Organ Prolapse | Not applicable | Enrolling by invitation | Dartmouth-Hitchcock Medical Center | 120 | 2025-10-10 | 2025-11-24 |
| Accelerometer Measured Early Recovery After Prolapse Surgery Postoperative Exercise regimen - Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP) | Not applicable | Recruiting | NICHD Pelvic Floor Disorders Network | 288 | 2025-10-02 | 2026-04-27 |
| Post-hysterectomy Vaginal Cuff Prolapse Repair Laparoscopic Lateral Suspension, Laparoscopic Sacrocolpopexy - Vaginal Cuff Complications | Not applicable | Recruiting | Kanuni Sultan Suleyman Training and Research Hospital | 50 | 2025-09-30 | 2025-09-16 |
| Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority Study Vaginal mesh surgery for apical prolapse, Robotic-assisted abdominal mesh surgery with Upsylon device (Boston Scientific - USA) for vaginal apical prolapse - Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery | Not applicable | Recruiting | University of Sao Paulo General Hospital | 86 | 2025-09-15 | 2026-01-22 |
| Hugo™ Robotic-Assisted Surgery (RAS) System in Gynecological Subjects (Embrace Gynecology) Robotic Assisted-Surgery (RAS) Hysterectomy - Uterine Fibroids (UF), Menstrual Disorders | Not applicable | Active not recruiting | Medtronic - MITG | 70 | 2025-08-28 | 2026-06-02 |
Showing 20 of 372. Sign in to see all of them.
Pelvic Organ Prolapse (274) · Uterine Prolapse (58) · Cystocele (38) · Urinary Incontinence (29) · Urinary Incontinence, Stress (27) · Rectal Prolapse (26) · Rectocele (20) · Pelvic Floor Disorders (12) · Sexual Dysfunction, Physiological (10) · Pain, Postoperative (8) · Hernia (7) · Patient Satisfaction (6) · Urinary Retention (6) · Encopresis (4)
Pathological Conditions, Anatomical (372) · Pathological Conditions, Signs and Symptoms (372) · Urogenital Diseases (137) · Female Urogenital Diseases and Pregnancy Complications (135) · Female Urogenital Diseases (133) · Male Urogenital Diseases (96) · Urologic Diseases (90) · Pelvic Organ Prolapse (72) · Genital Diseases (71) · Signs and Symptoms (67) · Genital Diseases, Female (60) · Uterine Diseases (60) · Urination Disorders (56) · Lower Urinary Tract Symptoms (52)
Laparoscopy (6) · Hysterectomy, Vaginal (4) · Laser Therapy (4) · Melanocyte-Stimulating Hormones (4) · Injections (3) · Physical Therapy Modalities (3) · Standard of Care (3) · Vaginal Smears (3) · Biofeedback, Psychology (2) · Bupivacaine (2) · Clinical Protocols (2) · Electric Stimulation (2) · Hematologic Tests (2) · Hysterectomy (2) · Pain Measurement (2)
The Cleveland Clinic (11) · Peking Union Medical College Hospital (10) · Assiut University (6) · Centre Hospitalier Universitaire de Nīmes (6) · Gaziosmanpasa Research and Education Hospital (6) · Kanuni Sultan Suleyman Training and Research Hospital (6) · University of North Carolina, Chapel Hill (6) · Ain Shams Maternity Hospital (5) · Riphah International University (5) · University of Alabama at Birmingham (5) · Charles University, Czech Republic (4) · Hartford Hospital (4) · Medical University of Vienna (4) · Medstar Health Research Institute (4) · NICHD Pelvic Floor Disorders Network (4)
United States (116) · Turkey (Türkiye) (29) · France (19) · China (18) · Egypt (17) · Canada (10) · Italy (10) · Denmark (9) · Israel (9) · Russia (8) · Austria (6) · Pakistan (6) · United Kingdom (6) · Germany (5) · Spain (5)
Lan Zhu (6) · Lan Zhu, MD (5) · Dimitri Sarlos, MD (3) · Dmitry Shkarupa, MD, PhD (3) · Kris Strohbehn, MD (3) · Andrea Morciano, M.D. (2) · Cheryl Iglesia, MD (2) · Christophe Courtieu (2) · Elisabetta Costantini, MD (2) · Elizabeth Geller, MD (2) · Gamze Nur Cimilli Senocak (2) · Jan Deprest, MD, PhD (2) · Myung Jae Jeon, MD, PhD (2) · Roy Lauterbach, MD (2) · Stefano Salvatore, MD (2)
PMID 34184246, PMID 33207004, PMID 22344353, PMID 25421934, PMID 29472143, PMID 30311680, PMID 33030871, PMID 10413222, PMID 10522604, PMID 10562780, PMID 11795640, PMID 14664880, PMID 14706597, PMID 14756739, PMID 15227649, PMID 1547052, PMID 16220584, PMID 17370026, PMID 17645604, PMID 18060968, PMID 18089200, PMID 19129334, PMID 1952199, PMID 19546759, PMID 19816918, PMID 19937315, PMID 19941278, PMID 20093905, PMID 20350640, PMID 20664388, PMID 21114648, PMID 21252735, PMID 21858540, PMID 21860294, PMID 21979458, PMID 22015881, PMID 22038880, PMID 22067717, PMID 22239416, PMID 2224266, PMID 22594310, PMID 22752014, PMID 22777367, PMID 22777368, PMID 22890409, PMID 23187047, PMID 23262939, PMID 23274792, PMID 23358016, PMID 23508540
U10HD041261 (2), U10HD041267 (2), U10HD054214 (2), U10HD054215 (2), K12AR084231 (1), K23HD115269 (1), R01HD061811 (1), RC1EB010649-01 (1), U01HD041249 (1), U01HD069031 (1), U10HD041250 (1), U10HD041263 (1), U10HD054136 (1), U10HD054241 (1), U10HD069006 (1)