5 completed. 5 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 5 |
| Phase 3 | 1 | Completed 1 |
Follow Primary Aldosteronism: new trials by email Literature Review of Primary Aldosteronism trials Research Report on Primary Aldosteronism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of CIN-107 in Adults With Primary Aldosteronism CIN-107 2 mg dosing, CIN-107 4 mg dosing, CIN-107 8 mg dosing - Primary Aldosteronism, Hyperaldosteronism | Phase 2 | Completed | AstraZeneca | 15 | 2021-03-08 | 2026-03-03 |
| Calcium Channel Blockade in Primary Aldosteronism Amlodipine - Primary Aldosteronism, Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral) | Phase 2 | Completed | Brigham and Women's Hospital | 15 | 2020-09-01 | 2025-04-15 |
| 11C-Metomidate PET/CT for Endocrine Hypertension and Characterisation of Adrenal Tumours 11C-Metomidate PET/CT imaging at Clinical Imaging Research Centre - Primary Aldosteronism Due to Aldosterone Producing Adenoma, Primary Aldosteronism | Phase 2 / Phase 3 | Completed | Changi General Hospital | 97 | 2019-12-30 | 2026-10-26 |
| DP13 - A Phase II Study in Patients With Primary Aldosteronism dexfadrostat phosphate - Primary Aldosteronism | Phase 2 | Completed | Damian Pharma AG | 35 | 2019-11-21 | 2024-11-22 |
| Open-label Study on Treatment of Primary Aldosteronism With Everolimus Everolimus 0.75 mg - Primary Aldosteronism | Phase 2 | Completed | University Hospital, Basel, Switzerland | 12 | 2017-05-22 | 2019-01-09 |
Hyperaldosteronism (5) · Adrenal Gland Neoplasms (1) · Neoplasm Metastasis (1)
Adrenal Gland Diseases (5) · Adrenocortical Hyperfunction (5) · Endocrine System Diseases (5) · Endocrine Gland Neoplasms (1) · Neoplasms (1) · Neoplasms by Site (1) · Neoplastic Processes (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
Amlodipine (1) · Everolimus (1)
AstraZeneca (1) · Brigham and Women's Hospital (1) · Changi General Hospital (1) · Damian Pharma AG (1) · University Hospital, Basel, Switzerland (1)
United States (2) · Italy (1) · Singapore (1) · Switzerland (1)
Anand Vaidya, MD (1) · Marc Y Donath, Prof. (1) · Paolo Mulatero, Prof (1)