2 completed, 1 recruiting. 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 2, Recruiting 1 |
Follow Pre-XDR-TB: new trials by email Literature Review of Pre-XDR-TB trials Research Report on Pre-XDR-TB
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Innovating(IN) Shorter(S), All- Oral, Precised(P), Individualized(I) Treatment Regimen(RE) for Rifampicin Resistant Tuberculosis(INSPIRE-TB) Bdq(Lzd)+Lfx(Mfx)+Cfz(Cs)+Pto+E+H+Z, A1, A2a - Multidrug Resistant Tuberculosis, Rifampicin Resistant Tuberculosis | Phase 3 | Recruiting | Huashan Hospital | 1050 | 2022-05-23 | 2025-04-06 |
| Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline, Delamanid and Linezolid) With the Current South African Standard of Care Bedaquiline Oral Tablet, Linezolid Oral Tablet, Delamanid in Oral Dosage Form - Tuberculosis, Pre-XDR-TB | Phase 3 | Completed | Wits Health Consortium (Pty) Ltd | 402 | 2019-08-22 | 2024-08-28 |
| Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis Pretomanid, Linezolid, Bedaquiline - Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant | Phase 3 | Completed | Global Alliance for TB Drug Development | 181 | 2017-11-21 | 2023-06-29 |
Tuberculosis, Multidrug-Resistant (3) · Extensively Drug-Resistant Tuberculosis (2) · Tuberculosis (2) · Tuberculosis, Pulmonary (1)
Actinomycetales Infections (3) · Bacterial Infections (3) · Bacterial Infections and Mycoses (3) · Gram-Positive Bacterial Infections (3) · Infections (3) · Mycobacterium Infections (3) · Lung Diseases (1) · Respiratory Tract Diseases (1) · Respiratory Tract Infections (1) · Tuberculosis (1)
Linezolid (2) · bedaquiline (2) · A(2)C (1) · Clofazimine (1) · Dosage Forms (1) · Levofloxacin (1) · OPC-67683 (1) · pretomanid (1)
Global Alliance for TB Drug Development (1) · Huashan Hospital (1) · Wits Health Consortium (Pty) Ltd (1)
South Africa (2) · China (1) · Georgia (1) · Moldova (1) · Russia (1)
Francesca Conradie (1) · Francesca M Conradie (1) · Wenhong Zhang, PHD (1)