4 completed, 1 recruiting, 1 terminated, 1 withdrawn. 7 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 7 | Completed 4, Recruiting 1, Terminated 1, Withdrawn 1 |
Follow Prader-Willi Syndrome: new trials by email Literature Review of Prader-Willi Syndrome trials Research Report on Prader-Willi Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tirzepatide in PWS, HO and GNSO Tirzepatide - Prader-Willi Syndrome, Hypothalamic Obesity | Phase 4 | Recruiting | Grace Kim | 36 | 2025-05-01 | 2025-09-16 |
| Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome Guanfacine Extended Release, Placebo - Prader-Willi Syndrome, Aggression | Phase 4 | Completed | Maimonides Medical Center | 15 | 2020-12-17 | 2024-08-19 |
| Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome Placebo, Guanfacine extended release (GXR) - Prader-Willi Syndrome | Phase 4 | Withdrawn | NYU Langone Health | 2019-12-01 | 2020-08-26 | |
| GH in Adults With PWS, Effect on Hypotonia Evaluated by Functional MRI, Relationship With Strength and Body Composition Growth hormone, Placebo - Prader-Willi Syndrome | Phase 4 | Completed | Corporacion Parc Tauli | 30 | 2017-06-19 | 2021-01-27 |
| Oxygen Versus Medical Air for Treatment of CSA in Prader Will Syndrome Medical Air vs Oxygen - Sleep Apnea, Central, Prader-Willi Syndrome | Phase 4 | Completed | The Hospital for Sick Children | 9 | 2016-09-01 | 2025-06-08 |
| Liraglutide Use in Prader-Willi Syndrome Liraglutide - Diabetes Mellitus Type 2, Prader Willi Syndrome | Phase 4 | Terminated | Vancouver General Hospital | 1 | 2012-02-01 | 2015-12-09 |
| Is There a Sensibility Increased in the Growth Hormone at Child With Prader-Willi Syndrome? Growth hormone (Genotonorm® or Omnitrope®), DEXA, blood tests, H.G.P.O, osseous age., biopsy - Prader-Willi Syndrome, Growth Hormone Deficiency | Phase 4 | Completed | University Hospital, Toulouse | 111 | 2009-01-01 | 2021-09-24 |
Obesity (2) · Abnormalities, Multiple (1) · Aggression (1) · Behavioral Symptoms (1) · Chromosome Disorders (1) · Congenital Abnormalities (1) · Diabetes Mellitus, Type 2 (1) · Dwarfism, Pituitary (1) · Excoriation Disorder (1) · Genetic Diseases, Inborn (1) · Intellectual Disability (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Neurologic Manifestations (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Imprinting Disorders (7) · Nutritional and Metabolic Diseases (7) · Overweight (7) · Abnormalities, Multiple (6) · Chromosome Disorders (6) · Congenital Abnormalities (6) · Genetic Diseases, Inborn (6) · Intellectual Disability (6) · Nervous System Diseases (6) · Neurobehavioral Manifestations (6) · Neurologic Manifestations (6) · Nutrition Disorders (6) · Overnutrition (6) · Obesity (5)
Growth Hormone (2) · Absorptiometry, Photon (1) · Biopsy (1) · Guanfacine (1) · Hematologic Tests (1) · Human Growth Hormone (1) · Liraglutide (1) · Tirzepatide (1)
Corporacion Parc Tauli (1) · Grace Kim (1) · Maimonides Medical Center (1) · NYU Langone Health (1) · The Hospital for Sick Children (1) · University Hospital, Toulouse (1) · Vancouver General Hospital (1)
United States (3) · Canada (2) · France (1) · Spain (1)
Deepan Singh, MD (2) · Jason Kong, MD, FRCPC (1) · Olga Gimenez-Palop, MD, PhD (1) · Reshma Amin, MD (1)
PMID 24406482, PMID 24916642, PMID 34040195, PMID 38561465
2017 (1)