2 not yet recruiting, 2 recruiting. 2 Phase 4, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 2 | Not yet recruiting 1, Recruiting 1 |
| Not applicable | 1 | Not yet recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Pleural Infections: new trials by email Literature Review of Pleural Infections trials Research Report on Pleural Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Role of Medical Thoracoscopy in Pleural Infection (PROMPT Trial) medical thoracoscopy, Standard of Care - Pleural Infection, Pleural Infections | Not applicable | Not yet recruiting | Università Politecnica delle Marche | 170 | 2026-11-01 | 2026-04-24 |
| VATS or Intrapleural Enzymatic Therapy for Patients With Empyema. VATS group, IET - Empyema, Pleural, Pleural Infections | Phase 4 | Not yet recruiting | Amsterdam UMC | 164 | 2026-10-01 | 2026-10-21 |
| Comparison of Early Pleural Irrigation Strategy With Saline to the Standard of Care for the Management of Complicated Pleural Infections. intrapleural irrigation, Standard care - Therapy, Pleural Infections | Phase 3 | Recruiting | Centre Hospitalier Universitaire, Amiens | 244 | 2026-05-13 | 2026-07-01 |
| Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema Fibrinolytic once daily, Fibrinolytic twice daily, DNA degradation once daily - Pleural Infection Bacterial, Pleural Infections | Phase 4 | Recruiting | University of North Carolina, Chapel Hill | 270 | 2025-09-11 | 2026-09-29 |
Empyema (2) · Empyema, Pleural (2) · Inflammation (2) · Pleural Effusion (1)
Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Infections (2) · Pleural Diseases (2) · Respiratory Tract Diseases (2) · Respiratory Tract Infections (2) · Suppuration (2) · Inflammation (1)
Standard of Care (2) · Anti-Bacterial Agents (1) · Thrombolytic Therapy (1)
Amsterdam UMC (1) · Centre Hospitalier Universitaire, Amiens (1) · University of North Carolina, Chapel Hill (1) · Università Politecnica delle Marche (1)
France (1) · United States (1)
PMID 21830966, PMID 32421353, PMID 37553157, PMID 39827129, PMID 41243095