16 not yet recruiting. 16 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 16 | Not yet recruiting 16 |
| Phase 2 | 2 | Not yet recruiting 2 |
Follow Neuroectodermal Tumors: new trials by email Literature Review of Neuroectodermal Tumors trials Research Report on Neuroectodermal Tumors
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Cerebraca Wafer Plus Temozolomide Versus Temozolomide Alone in Recurrent Glioblastoma Cerebraca wafer, Temozolomide (for relapsed malignant glioma) - Recurrent Glioblastoma, IDH-Wildtype | Phase 2 / Phase 3 | Not yet recruiting | Everfront Biotech Co., Ltd. | 175 | 2027-04-01 | 2026-09-10 |
| Safety and Efficacy Study of Safusidenib in Participants With Grade 2 IDH1-Mutant Glioma Safusidenib, Placebo - Grade 2 Glioma (Astrocytoma or Oligodendroglioma) With an IDH1 Mutation, Astrocytoma IDH Mutant Grade 2 | Phase 3 | Not yet recruiting | Nuvation Bio Inc. | 140 | 2027-03-01 | 2026-07-17 |
| Comparison of Neurocognitive Outcome in Two Standard Regimen for Treatment of Low-risk Medulloblastoma Bridging Chemotherapy, Induction Cycles A1-A3, Induction Cycles A4-5 - Medulloblastoma | Phase 3 | Not yet recruiting | Nationwide Children's Hospital | 96 | 2027-01-01 | 2026-10-20 |
| IMPT Versus IMRT for Diffuse Intrinsic Pontine Glioma Intensity-Modulated Proton Therapy (IMPT), Intensity-Modulated Radiation Therapy (IMRT) - Diffuse Intrinsic Pontine Gliomas (DIPG) | Phase 3 | Not yet recruiting | Shandong Cancer Hospital and Institute | 142 | 2026-12-01 | 2026-10-09 |
| PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma Chemical Exchange Saturation Transfer Magnetic Resonance Imaging, Contrast-enhanced Magnetic Resonance Imaging, Magnetic Resonance Imaging - Glioblastoma | Phase 3 | Not yet recruiting | Jonsson Comprehensive Cancer Center | 60 | 2026-12-01 | 2026-07-07 |
| iSCIB1+ in Combination With Ipilimumab and Nivolumab as First-Line Treatment for Advanced Unresectable Melanoma iSCIB1+, Nivolumab & Ipilimumab, Placebo - Melanoma (Skin Cancer), Advanced Melanoma | Phase 3 | Not yet recruiting | Scancell Ltd | 550 | 2026-12-01 | 2026-09-11 |
| Intraoperative Ultrasound for Brain Tumor Surgery Enhanced by AI BrainUS-AI real-time intraoperative ultrasound segmentation system - Brain Tumor Adult | Phase 3 | Not yet recruiting | Hospital del Rio Hortega | 100 | 2026-12-01 | 2026-09-17 |
| Somatostatin Analogues vs. Observation After Peptide Receptor Radionuclide Therapy (PRRT) in Nonfunctional Neuroendocrine Neoplasms Somatostatin Analogue(s) - Neuroendocrine Neoplasm, Gastroenteropancreatic Neuroendocrine Neoplasm | Phase 3 | Not yet recruiting | Washington University School of Medicine | 240 | 2026-11-30 | 2026-10-19 |
| SEMAFORCRANIO : Multicenter, Double-blind, Parallel, Randomized Controlled Trial of the Efficacy of Semaglutide in Hypothalamic Obesity Secondary to Craniopharyngioma in Children Aged 12 to 17 Years Semaglutide (Wegovy) weekly injection, Placebo weekly Injection - Craniopharyngioma, Child | Phase 3 | Not yet recruiting | University Hospital, Angers | 50 | 2026-11-01 | 2026-09-29 |
| Tris-CAR-T Cell Therapy Targeting CD44 and CD133 in Newly Diagnosed Glioblastoma Tris-CAR-T cell injection, Ommaya reservoir implantation, Temozolomide (TMZ) - Newly Diagnosed Glioblastoma, IDH-wildtype | Phase 2 / Phase 3 | Not yet recruiting | Beijing Tiantan Hospital | 60 | 2026-10-15 | 2026-10-14 |
| Superparamagnetic Iron Oxide for Sentinel Lymph Node Localization in Patients With Cutaneous Melanoma: MagMen-II Superparamagnetic Iron Oxide, Technetium (99mTc) - Melanoma (Skin Cancer) | Phase 3 | Not yet recruiting | Vastra Gotaland Region | 254 | 2026-10-01 | 2026-09-03 |
| ZG005 Plus Etoposide and Cisplatin vs. Etoposide and Cisplatin as First-Line Treatment for Advanced Neuroendocrine Carcinoma ZG005 for Injection, Etoposide Injection, Cisplatin Injection - Neuroendocrine Carcinomas (NEC) | Phase 3 | Not yet recruiting | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 440 | 2026-10-01 | 2026-09-22 |
| Clinical Benefit of 18F-FET in Glioma. 18F-Fluoroethyl-l-tyrosine - Glioma, 18F-Fluoroethyl-l-tyrosine | Phase 3 | Not yet recruiting | Primo Biotechnology Co., Ltd | 36 | 2026-10-01 | 2026-07-13 |
| A Study of ZG006 for Injection Versus Investigator-Selected Chemotherapy in Participants With Advanced Neuroendocrine Carcinoma ZG006, 5-fluorouracil, Calcium folinate and Irinotecan - Neuroendocrine Carcinoma | Phase 3 | Not yet recruiting | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 240 | 2026-07-01 | 2026-05-19 |
| Clinical Trial Assessing the Efficacy and Safety of Dendritic Cell-Based Immunotherapy for Glioblastoma Dendritic Cell Vaccine, Pembrolizumab, Placebo - Glioblastoma | Phase 3 | Not yet recruiting | University of Sao Paulo General Hospital | 186 | 2026-01-01 | 2025-04-01 |
| Study of Adding or Not Liposomal Transcrocetin (L-TC) With Concomitant HypoFractionated Radiation ThErapy and TEmozolomide in Newly Diagnosed GLioblastoma (GBM) Patients Administration of L-TC, Radiotherapy plus Temozolomide - Glioblastoma | Phase 3 | Not yet recruiting | Institut de cancérologie Strasbourg Europe | 554 | 2025-01-01 | 2024-06-27 |
Glioblastoma (6) · Brain Neoplasms (2) · Carcinoma, Neuroendocrine (2) · Glioma (2) · Melanoma (2) · Astrocytoma (1) · Carcinoid Tumor (1) · Craniopharyngioma (1) · Diffuse Intrinsic Pontine Glioma (1) · Hypoxia (1) · Medulloblastoma (1) · Neuroendocrine Tumors (1) · Oligodendroglioma (1) · Sexual Infantilism (1) · Skin Neoplasms (1)
Neoplasms (16) · Neoplasms by Histologic Type (16) · Neoplasms, Germ Cell and Embryonal (16) · Neoplasms, Nerve Tissue (16) · Neoplasms, Glandular and Epithelial (13) · Neoplasms, Neuroepithelial (10) · Glioma (8) · Astrocytoma (6) · Neoplasms by Site (5) · Neuroendocrine Tumors (4) · Adenocarcinoma (3) · Brain Diseases (3) · Carcinoma (3) · Central Nervous System Diseases (3)
Temozolomide (4) · Radiotherapy (3) · Cisplatin (1) · Contrast Media (1) · Etoposide (1) · Fluorouracil (1) · IFL protocol (1) · Injections (1) · Ipilimumab (1) · Irinotecan (1) · Leucovorin (1) · Magnetic Resonance Spectroscopy (1) · Nivolumab (1) · Radiation (1) · Radiotherapy, Intensity-Modulated (1)
Suzhou Zelgen Biopharmaceuticals Co.,Ltd (2) · Beijing Tiantan Hospital (1) · Everfront Biotech Co., Ltd. (1) · Hospital del Rio Hortega (1) · Institut de cancérologie Strasbourg Europe (1) · Jonsson Comprehensive Cancer Center (1) · Nationwide Children's Hospital (1) · Nuvation Bio Inc. (1) · Primo Biotechnology Co., Ltd (1) · Scancell Ltd (1) · Shandong Cancer Hospital and Institute (1) · University Hospital, Angers (1) · University of Sao Paulo General Hospital (1) · Vastra Gotaland Region (1) · Washington University School of Medicine (1)
United States (5) · China (4) · France (2) · Taiwan (1) · United Kingdom (1)
Girish Dhall, MD (1) · Jason Wu (1) · Kunal S Patel, MD (1) · Maryam Fouladi, MD (1) · Nikolaos Trikalinos, MD, MS (1) · Tao Jiang, MD, PhD (1) · Wei Zhang, MD, PhD (1)