2 completed, 1 recruiting, 1 terminated, 1 withdrawn. 5 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 2, Recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 1 | 2 | Recruiting 1, Withdrawn 1 |
Follow Morning Sickness: new trials by email Literature Review of Morning Sickness trials Research Report on Morning Sickness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hyperemesis Gravidarum Risk Reduction With Metformin Metformin Extended Release Oral Tablet - Hyperemesis Gravidarum | Phase 1 / Phase 2 | Recruiting | University of Southern California | 224 | 2026-07-13 | 2026-07-22 |
| Endeavor to Stop Nausea/Vomiting Associated With Pregnancy (E-SNAP) Mirtazapine - Pregnancy, Severe Nausea and Vomiting | Phase 1 / Phase 2 | Withdrawn | Northwestern University | 2022-06-13 | 2024-12-11 | |
| Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of Pregnancy Capsaicin Topical Cream, Metoclopramide, Ondansetron - Hyperemesis Gravidarum, Nausea Gravidarum | Phase 2 | Completed | Women and Infants Hospital of Rhode Island | 30 | 2022-05-24 | 2024-02-07 |
| Validating the Effect og Ondansetron and Mirtazapine in Treating Hyperemesis Gravidarum Mirtazapine, Ondansetron, Placebo - Hyperemesis Gravidarum, Nausea Gravidarum | Phase 2 | Terminated | Nordsjaellands Hospital | 58 | 2019-03-01 | 2023-01-30 |
| Comparison of Gabapentin and Metoclopramide for Treating Hyperemesis Gravidarum Gabapentin, Metoclopramide - Hyperemesis Gravidarum | Phase 2 | Completed | State University of New York at Buffalo | 31 | 2014-06-01 | 2023-02-14 |
Hyperemesis Gravidarum (5) · Nausea (5) · Vomiting (4)
Female Urogenital Diseases and Pregnancy Complications (5) · Pathological Conditions, Signs and Symptoms (5) · Pregnancy Complications (5) · Signs and Symptoms (5) · Signs and Symptoms, Digestive (5) · Urogenital Diseases (5) · Vomiting (1)
Metoclopramide (2) · Mirtazapine (2) · Ondansetron (2) · Gabapentin (1) · Ringer's Lactate (1)
Nordsjaellands Hospital (1) · Northwestern University (1) · State University of New York at Buffalo (1) · University of Southern California (1) · Women and Infants Hospital of Rhode Island (1)
United States (4) · Denmark (1)
Anne Ostenfeld, MD (1) · Katherine L Wisner, M.D., M.S. (1) · Lauren Murphy, MD (1) · Marlena Fejzo, PhD (1)
PMID 32209630, PMID 33451591, PMID 37271593, PMID 41478546
R01HD076313 (1), R21HD105101 (1)