15 completed. 15 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 15 | Completed 15 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Malignant Neoplasm: new trials by email Literature Review of Malignant Neoplasm trials Research Report on Malignant Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1) nab-sirolimus - Tumor, Tumor, Solid | Phase 2 | Completed | Aadi Bioscience, Inc. | 128 | 2022-03-10 | 2026-10-28 |
| Perioperative Ostomy Self-Management Telehealth for Cancer Patients and Family Caregivers Informational Intervention, Quality-of-Life Assessment, Questionnaire Administration - Malignant Neoplasm | Phase 2 | Completed | City of Hope Medical Center | 6 | 2020-01-23 | 2023-05-16 |
| MOM's PAIN (Methylene Blue for Oral Mucositis' PAIN) Best Practice, Methylene Blue - Malignant Neoplasm, Oral Pain | Phase 2 | Completed | M.D. Anderson Cancer Center | 69 | 2019-02-28 | 2023-04-25 |
| Low-Dose Ibuprofen in Improving Cognitive Impairment in Patients With Cancer Ibuprofen, Placebo, Questionnaire Administration - Cognitive Impairment, Malignant Neoplasm | Phase 2 | Completed | University of Rochester NCORP Research Base | 87 | 2017-05-26 | 2023-09-25 |
| Netupitant and Palonosetron Hydrochloride in Preventing Chronic Nausea and Vomiting in Patients With Cancer Netupitant, Palonosetron, Palonosetron Hydrochloride - Malignant Neoplasm, Nausea | Phase 2 / Phase 3 | Completed | M.D. Anderson Cancer Center | 53 | 2017-05-03 | 2023-10-17 |
| Netupitant and Palonosetron Hydrochloride in Preventing Chemotherapy Induced Nausea and Vomiting in Patients With Cancer Undergoing BEAM Conditioning Regimen Before Stem Cell Transplant Netupitant, Palonosetron Hydrochloride, Questionnaire Administration - Malignant Neoplasm | Phase 2 | Completed | OHSU Knight Cancer Institute | 43 | 2017-04-27 | 2021-07-12 |
| Combine TACE and Autologous Tcm Immunotherapy Versus TACE Alone for HCC With MVI After Radical Resection TACE plus autologous Tcm immunotherapy, TACE - Hepatocellular Carcinoma, Malignant Neoplasm | Phase 2 | Completed | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 52 | 2017-01-09 | 2020-06-11 |
| High Dose Flu Vaccine in Treating Children Who Have Undergone Donor Stem Cell Transplant Trivalent Influenza Vaccine, Quadrivalent Influenza Vaccine, Laboratory Biomarker Analysis - Hematopoietic Cell Transplantation Recipient, Malignant Neoplasm | Phase 2 | Completed | Vanderbilt-Ingram Cancer Center | 170 | 2016-09-01 | 2024-10-22 |
| Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies Fludarabine, Total-Body Irradiation, T Cell-Depleted Donor Lymphocyte Infusion - Acute Myeloid Leukemia, Acute Myeloid Leukemia in Remission | Phase 2 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 35 | 2015-11-13 | 2025-04-24 |
| Ponatinib for Patients Whose Advanced Solid Tumor Cancer Has Activating Mutations Involving the Following Genes: FGFR1, FGFR2, FGFR3, FGFR4, RET, KIT. ponatinib hydrochloride, laboratory biomarker analysis - Malignant Neoplasm | Phase 2 | Completed | Sameek Roychowdhury | 22 | 2015-02-24 | 2025-03-24 |
| Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures placebo administration, EMLA, propofol - Malignant Neoplasm | Phase 2 | Completed | Wake Forest University Health Sciences | 33 | 2012-05-14 | 2019-09-06 |
| Donor Atorvastatin Treatment for Preventing Severe Acute Graft-Versus-Host Disease in Patients Undergoing Myeloablative Peripheral Blood Stem Cell Transplantation Allogeneic Hematopoietic Stem Cell Transplantation, Atorvastatin Calcium, Peripheral Blood Stem Cell Transplantation - Malignant Neoplasm | Phase 2 | Completed | Fred Hutchinson Cancer Center | 83 | 2012-05-01 | 2017-08-17 |
| Evaluation of Food Effect on Pharmacokinetics of Vismodegib Pharmacological Study, Vismodegib - Malignant Neoplasm | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 63 | 2009-10-01 | 2017-05-19 |
| Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer bevacizumab, placebo, magnetic resonance imaging - Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma | Phase 2 | Completed | National Cancer Institute (NCI) | 11 | 2007-06-01 | 2014-05-09 |
| CCI-779 in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia temsirolimus - B-cell Chronic Lymphocytic Leukemia, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Phase 2 | Completed | National Cancer Institute (NCI) | 89 | 2004-03-01 | 2014-05-23 |
Neoplasms (15) · Anemia, Aplastic (1) · Anemia, Refractory (1) · Anemia, Refractory, with Excess of Blasts (1) · Astrocytoma (1) · Brain Neoplasms (1) · Burkitt Lymphoma (1) · Carcinoma, Hepatocellular (1) · Choroid Plexus Neoplasms (1) · Cognitive Dysfunction (1) · Ependymoma (1) · Esthesioneuroblastoma, Olfactory (1) · Glioma (1) · Hemangiopericytoma, Malignant (1) · Hereditary Sensory and Autonomic Neuropathies (1)
Neoplasms by Histologic Type (4) · Pathological Conditions, Signs and Symptoms (4) · Pathologic Processes (3) · Blood Protein Disorders (2) · Carcinoma (2) · Cardiovascular Diseases (2) · Chronic Disease (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Disease Attributes (2) · Genetic Diseases, Inborn (2) · Hematologic Diseases (2) · Hemic and Lymphatic Diseases (2) · Hemorrhagic Disorders (2) · Hemostatic Disorders (2) · Immune System Diseases (2)
Palonosetron (2) · Peripheral Blood Stem Cell Transplantation (2) · netupitant (2) · Atorvastatin (1) · Bevacizumab (1) · Cyclophosphamide (1) · Fentanyl (1) · HhAntag691 (1) · Ibuprofen (1) · Influenza Vaccines (1) · Lidocaine, Prilocaine Drug Combination (1) · Magnetic Resonance Spectroscopy (1) · Methylene Blue (1) · Mycophenolic Acid (1) · Practice Guidelines as Topic (1)
National Cancer Institute (NCI) (3) · M.D. Anderson Cancer Center (2) · Aadi Bioscience, Inc. (1) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · City of Hope Medical Center (1) · Fred Hutchinson Cancer Center (1) · OHSU Knight Cancer Institute (1) · Sameek Roychowdhury (1) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1) · University of Rochester NCORP Research Base (1) · Vanderbilt-Ingram Cancer Center (1) · Wake Forest University Health Sciences (1)
United States (14) · China (1) · Puerto Rico (1) · South Korea (1)
Carlos Roldan (1) · David Hui (1) · Dudley Hammon (1) · Hong Zhao (1) · Joseph Bubalo (1) · Manish Sharma (1) · Marco Mielcarek (1) · Michelle C Janelsins (1) · Monica Loghin (1) · Natasha Halasa, MD, MPH (1) · Sameek Roychowdhury, MD, PhD (1) · Sonali Smith (1) · Usama Gergis, MD (1) · Virginia Sun (1)
PMID 20837940, PMID 33388382, PMID 34926296, PMID 36324139, PMID 37800415, PMID 39279435
N01CM62202 (2), P30CA014599 (2), N01CM62201 (1), P30CA015704 (1), P30CA016672 (1), P30CA033572 (1), R01HL108307 (1), R21CA187500 (1), U01CA069852 (1), UG1CA189961 (1)